# Anne Marie Staub

**Anne Marie Staub** (1914–2012) was a French biochemist and chemist at the Institut Pasteur whose career spans two notable claims: early antihistamine research with [Daniel Bovet](https://www.edgepedia.org/daniel-bovet) in 1937, and a 1950s–1960s program on the chemical basis of Salmonella O-antigen specificity. She headed a laboratory at the [Pasteur Institute](https://www.edgepedia.org/pasteur-institute) from 1953 and co-directed, with Marcel Raynaud, the institute's *Cours d'immunologie générale et de sérologie*.<sup>[1](https://www.sudoc.fr/019840136)</sup><sup> • </sup><sup>[7](https://catalogue.bnf.fr/ark:/12148/cb12896264x)</sup>

| Key fact | Detail |
|---|---|
| Life dates | 1914–2012, per the French library authority record and catalog entries<sup>[1](https://www.sudoc.fr/019840136)</sup> |
| Editorial role | Scientific editor, with Marcel Raynaud, of the *Cours d'immunologie générale et de sérologie de l'Institut Pasteur*<sup>[1](https://www.sudoc.fr/019840136)</sup> |
| Signature paper | Corresponding author, "Chemical Basis of Immunological Specificity of Salmonella Antigens", *Annales de l'Institut Pasteur*, 1960 |
| Major review | Co-author, "Immunochemistry of O and R antigens of Salmonella and related Enterobacteriaceae", *Bacteriological Reviews* 1966;30(1):192–255<sup>[2](https://doi.org/10.1016/0019-2791(76)90331-1)</sup> |

## Training and the 1937 antihistamine work

In 1937, the account states, Staub and Bovet demonstrated a compound capable of attenuating the symptoms of a severe allergic reaction, an early demonstration of antihistamine activity.

## Career at the Institut Pasteur

In 1953 Staub became head of a laboratory at the Institut Pasteur.

**Editorial seniority.** [Library catalog](https://www.edgepedia.org/library-catalog) records list her as scientific editor, with Marcel Raynaud, of the *Cours d'immunologie générale et de sérologie de l'Institut Pasteur*, a multi-edition course text published under the direction of the two, with a large collaborating author list.<sup>[1](https://www.sudoc.fr/019840136)</sup> A second catalog record styles her "Directeur de publication" of the same work.<sup>[3](https://www.sudoc.fr/019887000)</sup> The fifth revised edition, directed by Staub and Raynaud, appeared in 1971 and ran to 272 pages, covering serological examination, blood groups, immunology, and medicine.<sup>[4](https://santepsy.ascodocpsy.org/index.php?id=24190&lvl=notice_display)</sup>

## Research contributions: Salmonella immunochemistry

Staub's documented publication record lies in the immunochemistry of bacterial surface antigens. She was corresponding author of "Chemical Basis of Immunological Specificity of Salmonella Antigens" in the *Annales de l'Institut Pasteur* (1960).<sup>[8](https://cabdirect.org/cabdirect/abstract/19612700235)</sup>

Two further records document the collaboration with Westphal. A French-language paper on the chemical and biochemical study of the immunologic specificity of bacterial polysaccharides appeared in the *Bulletin de la Société de Chimie Biologique* in 1964 (volume 46, pages 1647–1684; PMID 14274190).<sup>[5](https://staging.europepmc.org/article/MED/14274190)</sup> The collaboration culminated in the review "Immunochemistry of O and R antigens of Salmonella and related Enterobacteriaceae", *Bacteriological Reviews*, 1966, volume 30, part 1, pages 192–255 (doi:10.1128/br.30.1.192-255.1966).<sup>[2](https://doi.org/10.1016/0019-2791(76)90331-1)</sup>

## A woman in French biochemistry

The Pasteur Institute itself has described a pattern that bears on Staub's legacy.

## References

1. [Sudoc catalogue: Cours d'immunologie générale et de sérologie de l'Institut Pasteur](https://www.sudoc.fr/019840136)
2. [Immunochemistry of O and R antigens of Salmonella and related Enterobacteriaceae, Bacteriological Reviews 1966, publication record](https://doi.org/10.1016/0019-2791(76)90331-1)
3. [Sudoc catalogue record (second record), Cours d'immunologie générale et de sérologie](https://www.sudoc.fr/019887000)
4. [Base SantéPsy catalogue record for STAUB AM (1971 fifth edition)](https://santepsy.ascodocpsy.org/index.php?id=24190&lvl=notice_display)
5. [STAUB AM, WESTPHAL O, Bulletin de la Société de Chimie Biologique 1964, Europe PMC record](https://staging.europepmc.org/article/MED/14274190)
6. [pmc.ncbi.nlm.nih.gov](https://pmc.ncbi.nlm.nih.gov/articles/PMC7012941/)
7. [Notice de personne "Staub, Anne-Marie (1914-2012)", Bibliothèque nationale de France](https://catalogue.bnf.fr/ark:/12148/cb12896264x)
8. [Chemical Basis of Immunological Specificity of Salmonella Antigens, CAB Direct](https://cabdirect.org/cabdirect/abstract/19612700235)

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*Topic: Encyclopedia › Life and health › Life and health scientists › Life scientists › Researchers in structural biology, biochemistry, and biophysics*

*Initially written Oct 10, 2026 · Edited: Oct 11, 2026; Oct 15, 2026; Oct 21, 2026; Oct 25, 2026*

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License: Edgepedia Community License 1.0, https://www.edgepedia.org/edgepedia/license