{ "id": "epjccwrznm", "slug": "atom-probe-tomography", "title": "Atom probe tomography", "updated": "2026-09-30", "topic_path": [ { "id": "technology", "label": "Technology and the built world", "api_url": "https://www.edgepedia.org/api/v1/topics/technology" }, { "id": "technology.engineering", "label": "Engineering and manufacturing", "api_url": "https://www.edgepedia.org/api/v1/topics/technology.engineering" }, { "id": "technology.engineering.engineering.materials.metallurgy", "label": "Materials science and metallurgy", "api_url": "https://www.edgepedia.org/api/v1/topics/technology.engineering.engineering.materials.metallurgy" } ], "geo": [ { "id": "geo.nongeo.t1946.technology.engineering.engineering.materials.metallurgy", "label": "Non-geographic · 1946 to 2000: Materials science and metallurgy", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo.t1946.technology.engineering.engineering.materials.metallurgy", "path": [ { "id": "geo.nongeo", "label": "Non-geographic", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo" }, { "id": "geo.nongeo.t1946", "label": "Non-geographic · 1946 to 2000", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo.t1946" }, { "id": "geo.nongeo.t1946.technology", "label": "Technology and the built world", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo.t1946.technology" }, { "id": "geo.nongeo.t1946.technology.engineering", "label": "Engineering and manufacturing", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo.t1946.technology.engineering" }, { "id": "geo.nongeo.t1946.technology.engineering.engineering.materials.metallurgy", "label": "Materials science and metallurgy", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo.t1946.technology.engineering.engineering.materials.metallurgy" } ] }, { "id": "geo.nongeo.t2001.technology.engineering", "label": "Non-geographic · 2001 to 2020: Engineering and manufacturing", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo.t2001.technology.engineering", "path": [ { "id": "geo.nongeo", "label": "Non-geographic", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo" }, { "id": "geo.nongeo.t2001", "label": "Non-geographic · 2001 to 2020", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo.t2001" }, { "id": "geo.nongeo.t2001.technology", "label": "Technology and the built world", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo.t2001.technology" }, { "id": "geo.nongeo.t2001.technology.engineering", "label": "Engineering and manufacturing", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo.t2001.technology.engineering" } ] } ], "excerpt": "Atom probe tomography (APT) is an analytical microscopy technique that maps the 3D positions and elemental identities of individual atoms in a needle-shaped specimen, with sub-nanometer resolution and parts-per-million sensitivity.", "snippet": "Atom probe tomography (APT) is an analytical microscopy technique that maps the 3D positions and elemental identities of individual atoms in a needle-shaped specimen, with sub-nanometer resolution and parts-per-million sensitivity.", "node": "technology.engineering.engineering.materials.metallurgy", "markdown": "# Atom probe tomography\n\nAtom probe tomography (APT) is an analytical microscopy technique that reconstructs the three-dimensional positions and elemental identities of individual atoms in a needle-shaped specimen. Each detected ion is recorded with lateral x and y impact coordinates, a time of flight giving a mass-to-charge identity, and reconstructed three-dimensional positions, producing a sub-nanometer 3D elemental map with sensitivity in the parts-per-million range for any element.[1](https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=936728) It detects elements from hydrogen to uranium at detection limits of about 10 ppm, on the order of \\( 10^{17} \\) to \\( 10^{18} \\) atoms/cm³ depending on the material's atomic density, and a typical modern dataset contains 10 to 100 million atoms.[2](https://www.eag.com/wp-content/uploads/2020/10/M-052520-APT-technique-note_w.pdf) • [3](https://www.nature.com/articles/s41467-024-54169-2)\n\n| Key fact | Value |\n| --- | --- |\n| Data product | Point cloud of atoms with x, y, z coordinates, and mass-to-charge identity[1](https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=936728) • [4](https://research.chalmers.se/publication/542321/file/542321_Fulltext.pdf) |\n| Evaporation conditions | 1–10 kV standing voltage; fields of 10–50 V/nm on a needle with sub-100 nm apex[1](https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=936728) |\n| Chemical identification | Time-of-flight converted to mass-to-charge ratio \\( m/q \\) in Daltons[5](https://myscope.training/pdf/MyScope_APT.pdf) |\n| Specimen | Needle with 20–100 nm apex curvature radius[3](https://www.nature.com/articles/s41467-024-54169-2) |\n| Detection efficiency | Up to ~80% (LEAP 5000 XS); 52% on the LEAP 6000 XR[6](https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=931795) • [7](https://www.nature.com/articles/s41529-025-00626-2) • [4](https://research.chalmers.se/publication/542321/file/542321_Fulltext.pdf) |\n| Analyzed volume | (50–100) × (50–100) × (200–1000) nm³ in modern datasets[3](https://www.nature.com/articles/s41467-024-54169-2) |\n| Mass resolving power | Up to ~500 (voltage-pulsed), ~1000 (laser-pulsed), >2000 (reflectron-equipped)[5](https://myscope.training/pdf/MyScope_APT.pdf) |\n\n## How it works\n\nAPT, like the field ion microscope, is a point-projection microscope in which the specimen itself acts as the projection optic, with no additional lenses.[8](https://pmc.ncbi.nlm.nih.gov/articles/PMC10502706/) The specimen is a needle with an apex below 100 nm in diameter, held at a standing voltage of 1 kV to 10 kV. This creates a surface field of 10–50 V/nm, high enough that atoms at the apex are close to field-evaporating.[1](https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=936728) A voltage pulse or a laser pulse then triggers evaporation atom by atom: the rate of evaporation is increased either by lowering the potential energy barrier of surface atoms through a higher field (voltage pulse) or by raising the temperature with a thermal laser pulse.[1](https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=936728) Each ion flies to a position-sensitive detector, and its time of flight is converted into a mass-to-charge ratio \\( m/q \\) in Daltons, which chemically identifies the ion.[5](https://myscope.training/pdf/MyScope_APT.pdf) The detector impact position gives the lateral coordinates, and the ion sequence order gives the depth, yielding a reconstructed volume with the position and identity of each detected atom.[4](https://research.chalmers.se/publication/542321/file/542321_Fulltext.pdf)\n\n## How it is done\n\nSpecimens are most commonly prepared by FIB lift-out: a wedge is cut, welded to a sacrificial post (tungsten, silicon, or a TEM grid bar), sculpted with a Ga⁺ ion beam, and capped with Ni, Cr, or FIB-deposited Pt to prevent Ga implantation.[1](https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=936728) [In situ](https://www.edgepedia.org/in-situ) site-specific FIB preparation for APT was reported by K. Thompson and colleagues in 2006.[9](https://doi.org/10.1016/j.ultramic.2006.06.008) Annular milling proceeds first at 30 kV Ga and then at 2–5 kV for final sharpening, giving tips under 100 nm diameter with very low Ga implantation.[10](https://smeng.ucsd.edu/wp-content/uploads/Three-dimensional-nanoscale-characterisation-of-materials-by-atom-probe-tomography.pdf) During analysis the needle is held at cryogenic temperature to freeze out thermal motion of surface atoms.[11](https://www.cambridge.org/core/services/aop-cambridge-core/content/view/EC550AA096A3B2D578C1A0FBF8BC69CF/S0883769420000986a.pdf/the-ultimate-microscopyenabling-nanotechnology.pdf) [Reconstruction](https://www.edgepedia.org/reconstruction) then applies the point-projection protocol published by P. Bas, A. Bostel, B. Deconihout, and D. Blavette in 1995: it assumes the first detected ion evaporates from a hemispherical surface, and the depth of this emitting surface moves down by an increment proportional to the atomic volume within the material's lattice.[12](https://doi.org/10.1016/0169-4332%2894%2900561-3) • [6](https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=931795)\n\n## Origin\n\nThe lineage begins with the field ion microscope, for which Erwin W. Müller and Kanwar Bahadur reported field ionization of gases at a metal surface and the microscope's resolution in [Physical Review](https://www.edgepedia.org/physical-review) in 1956; this earlier work is what the atom probe built on.[13](https://doi.org/10.1103/physrev.102.624) The atom-probe field ion microscope, combining that imaging with a mass spectrometer, was reported by Erwin W. Müller, John A. Panitz, and S. Brooks McLane in the Review of Scientific Instruments in 1968.[14](https://doi.org/10.1063/1.1683116) Participant accounts and a manufacturer history date the completion of the first working instrument to 1967, a year earlier than the paper.[15](https://panitz.unm.edu/apfim/History_files/History%20of%20the%20Atom%20Probe.pdf) • [11](https://www.cambridge.org/core/services/aop-cambridge-core/content/view/EC550AA096A3B2D578C1A0FBF8BC69CF/S0883769420000986a.pdf/the-ultimate-microscopyenabling-nanotechnology.pdf) G. L. Kellogg and T. T. Tsong reported pulsed-laser atom-probe field-ion microscopy in 1980.[16](https://doi.org/10.1063/1.327686) A. Cerezo and colleagues reported the position-sensitive atom probe (PoSAP) in the Journal of Microscopy in 1989; its serial detection was its major limitation, and later designs moved to parallel detection.[17](https://doi.org/10.1111/j.1365-2818.1989.tb00584.x) • [18](https://panitz.unm.edu/home/References_files/Seidman_%282007a%29.pdf) The first local electrode atom probe (LEAP) was sold in 2003.[11](https://www.cambridge.org/core/services/aop-cambridge-core/content/view/EC550AA096A3B2D578C1A0FBF8BC69CF/S0883769420000986a.pdf/the-ultimate-microscopyenabling-nanotechnology.pdf)\n\n## Variants\n\nVoltage-pulsed versus laser-pulsed: nanosecond voltage pulses can only be transmitted by conductive materials, which limits voltage-pulsed APT to metals; femto- or picosecond laser pulses superposed on the standing field extended the technique to semiconductors and thin insulator layers.[19](https://www.sciencedirect.com/science/article/abs/pii/S0304399113000715) [B. Gault](https://www.edgepedia.org/baptiste-gault) and colleagues designed a femtosecond-laser-assisted tomographic atom probe in 2006.[20](https://doi.org/10.1063/1.2194089) Laser spot size and its positioning relative to the tip apex measurably affect mass resolution.[19](https://www.sciencedirect.com/science/article/abs/pii/S0304399113000715) The local electrode geometry combined with micron-size laser spots and 10 ps near-UV (355 nm) pulses defines the LEAP 5000 series, introduced in 2015, with detection efficiency reaching 80%.[6](https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=931795) Local electrode technology raised data collection rates to 5,000,000 ions/min with fields of view up to 200 nm.[21](https://iopscience.iop.org/article/10.1088/1742-6596/209/1/012026/pdf) The LEAP 6000 XR, the latest generation, adds a deep-UV laser of 257.5 nm wavelength and 52% detector efficiency, and introduces a synchronous voltage-plus-laser pulsing (VLP) mode, reported by F. Vurpillot and colleagues in 2024, that applies both pulses at once; since most spectral background comes from out-of-time evaporation under the standing voltage, the background drops significantly.[7](https://www.nature.com/articles/s41529-025-00626-2) • [22](https://www.cameca.com/products/apt/leap-6000) • [23](https://doi.org/10.1093/mam/ozae044.030)\n\n## Applications\n\nAPT answers questions about nucleation and clustering, grain-boundary segregation, dopant gradients, and buried interfaces.[1](https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=936728) It is used on high-temperature superalloys, power-plant structural materials, 3D dopant visualization in nanoscale transistors, GaN LEDs, hydrogen studies, and geological radioisotope dating verification; nearly all leading semiconductor manufacturers use APT in R&D or near the fab.[11](https://www.cambridge.org/core/services/aop-cambridge-core/content/view/EC550AA096A3B2D578C1A0FBF8BC69CF/S0883769420000986a.pdf/the-ultimate-microscopyenabling-nanotechnology.pdf) Cryogenic APT enabled direct observation of individual hydrogen atoms at trapping sites in a ferritic steel, reported by Y.-S. Chen and colleagues in Science in 2017,[24](https://doi.org/10.1126/science.aal2418) and nanoscale 3D lithium compositional fluctuation in Li-ion battery cathodes, reported by A. Devaraj and colleagues in [Nature Communications](https://www.edgepedia.org/nature-communications) in 2015.[25](https://doi.org/10.1038/ncomms9014) Quasi-in situ cryogenic-transfer APT now analyzes hydrogen diffusion in metallic alloys.[7](https://www.nature.com/articles/s41529-025-00626-2) A 2024 development integrated APT within transmission electron microscopes for correlative workflows.[3](https://www.nature.com/articles/s41467-024-54169-2) APT is routinely correlated with STEM, EBIC, EBSD, electron tomography, and SIMS.[2](https://www.eag.com/wp-content/uploads/2020/10/M-052520-APT-technique-note_w.pdf)\n\n## Limitations and alternatives\n\nRecognized evaporation defects affecting compositional accuracy include preferential retention of strongly bound atoms while weakly bound atoms evaporate first, multi-hit events during a single pulse, detector pile-up at high detection rates, complex molecules and spectral overlaps, molecular dissociation, and loss of neutral species.[10](https://smeng.ucsd.edu/wp-content/uploads/Three-dimensional-nanoscale-characterisation-of-materials-by-atom-probe-tomography.pdf) Specimen fracture is a common premature termination: the fields needed for evaporation create stresses approaching the material's ultimate tensile strength, so microstructural defects can cause mechanical failure.[10](https://smeng.ucsd.edu/wp-content/uploads/Three-dimensional-nanoscale-characterisation-of-materials-by-atom-probe-tomography.pdf) In multi-material devices such as Si FinFETs, varied thermal and absorption properties lead to errors in the reconstructed shape or apparent mixing of layers.[1](https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=936728) The relatively low number of counts, in the millions to low billions, also limits sensitivity.[26](https://www.ovid.com/journals/mimic/fulltext/10.1093/mam/ozag064~spatial-resolutions-in-atom-probe-tomography) TEM and atom-probe analysis are both powerful for routine microstructural characterization, and their combined use is synergistic.[27](https://onlinelibrary.wiley.com/doi/10.1002/jemt.1060080207)\n\n## References\n\n1. [Atom Probe Tomography of Electronic Materials and Devices (NIST)](https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=936728)\n2. [Atom Probe Tomography technique note (EAG Laboratories)](https://www.eag.com/wp-content/uploads/2020/10/M-052520-APT-technique-note_w.pdf)\n3. [Bringing atom probe tomography to transmission electron microscopes (Nature Communications, 2024)](https://www.nature.com/articles/s41467-024-54169-2)\n4. [Revisiting Compositional Accuracy of Carbides Using a Decreased Detector Efficiency in a LEAP 6000 XR Atom Probe Instrument](https://research.chalmers.se/publication/542321/file/542321_Fulltext.pdf)\n5. [MyScope APT training module (Microscopy Australia)](https://myscope.training/pdf/MyScope_APT.pdf)\n6. [Atom probe tomography introductory overview (NIST/Gault et al.)](https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=931795)\n7. [Insights from quasi-in situ cryogenic-transfer atom probe tomography for analyzing hydrogen diffusion in metallic alloys (npj Materials Degradation, 2025)](https://www.nature.com/articles/s41529-025-00626-2)\n8. [Atom probe tomography (review, 2023)](https://pmc.ncbi.nlm.nih.gov/articles/PMC10502706/)\n9. [K. Thompson and colleagues (2006). In situ site-specific specimen preparation for atom probe tomography. Ultramicroscopy.](https://doi.org/10.1016/j.ultramic.2006.06.008)\n10. [Three-dimensional nanoscale characterisation of materials by atom probe tomography](https://smeng.ucsd.edu/wp-content/uploads/Three-dimensional-nanoscale-characterisation-of-materials-by-atom-probe-tomography.pdf)\n11. [The ultimate microscopy, enabling nanotechnology (CAMECA white paper, MRS Bulletin 2020)](https://www.cambridge.org/core/services/aop-cambridge-core/content/view/EC550AA096A3B2D578C1A0FBF8BC69CF/S0883769420000986a.pdf/the-ultimate-microscopyenabling-nanotechnology.pdf)\n12. [A general protocol for the reconstruction of 3D atom probe data (Applied Surface Science, 1995)](https://doi.org/10.1016/0169-4332%2894%2900561-3)\n13. [Erwin W. Müller, Kanwar Bahadur (1956). Field Ionization of Gases at a Metal Surface and the Resolution of the Field Ion Microscope. Physical Review.](https://doi.org/10.1103/physrev.102.624)\n14. [Erwin W. Müller, John A. Panitz, S. Brooks McLane (1968). The Atom-Probe Field Ion Microscope. Review of Scientific Instruments.](https://doi.org/10.1063/1.1683116)\n15. [History of the Atom Probe: An Odyssey](https://panitz.unm.edu/apfim/History_files/History%20of%20the%20Atom%20Probe.pdf)\n16. [G. L. Kellogg, T. T. Tsong (1980). Pulsed-laser atom-probe field-ion microscopy. Journal of Applied Physics.](https://doi.org/10.1063/1.327686)\n17. [A. Cerezo and colleagues (1989). Materials analysis with a position‐sensitive atom probe. Journal of Microscopy.](https://doi.org/10.1111/j.1365-2818.1989.tb00584.x)\n18. [Three-Dimensional Atom-Probe Tomography: Advances and Applications (Seidman, 2007)](https://panitz.unm.edu/home/References_files/Seidman_%282007a%29.pdf)\n19. [Optimal laser positioning for laser-assisted atom probe tomography (Ultramicroscopy)](https://www.sciencedirect.com/science/article/abs/pii/S0304399113000715)\n20. [B. Gault and colleagues (2006). Design of a femtosecond laser assisted tomographic atom probe. Review of Scientific Instruments.](https://doi.org/10.1063/1.2194089)\n21. [Nanoscale characterization of compound semiconductors using laser-pulsed atom probe (Müller et al., 2010)](https://iopscience.iop.org/article/10.1088/1742-6596/209/1/012026/pdf)\n22. [LEAP 6000 XR - 3D Atom Probe](https://www.cameca.com/products/apt/leap-6000)\n23. [F Vurpillot and colleagues (2024). A Model to Optimize the Voltage Plus Laser Pulsing Mode in APT. Microscopy and Microanalysis.](https://doi.org/10.1093/mam/ozae044.030)\n24. [Y.-S. Chen and colleagues (2017). Direct observation of individual hydrogen atoms at trapping sites in a ferritic steel. Science.](https://doi.org/10.1126/science.aal2418)\n25. [A. Devaraj and colleagues (2015). Visualizing nanoscale 3D compositional fluctuation of lithium in advanced lithium-ion battery cathodes. Nature Communications.](https://doi.org/10.1038/ncomms9014)\n26. [Spatial Resolution(s) in Atom Probe Tomography (Microscopy and Microanalysis)](https://www.ovid.com/journals/mimic/fulltext/10.1093/mam/ozag064~spatial-resolutions-in-atom-probe-tomography)\n27. [Comparison of TEM and APFIM in microstructural characterization and interpretation: An overview](https://onlinelibrary.wiley.com/doi/10.1002/jemt.1060080207)\n\n---\n*Topic: Encyclopedia › Technology and the built world › Engineering and manufacturing › Materials science and metallurgy*\n\n*Initially written Sep 29, 2026 · Reviewed: Sep 30, 2026 · Edited: Sep 30, 2026 · Last review: Sep 30, 2026*\n\n*Copyright 2026 EdgeChat AI, a subsidiary of Biostate AI.*\n\nLicense: Edgepedia Community License 1.0, https://www.edgepedia.org/edgepedia/license\n", "same_as": [], "url": "https://www.edgepedia.org/atom-probe-tomography", "markdown_url": "https://www.edgepedia.org/atom-probe-tomography.md", "license": { "name": "Edgepedia Community License 1.0", "url": "https://www.edgepedia.org/edgepedia/license", "summary": "Free with credit, commercial use included. AI training is open to everyone. For other uses, organizations over USD 100M in revenue or 100M monthly users license separately.", "spdx": "LicenseRef-Edgepedia-Community-1.0" }, "credit": "\"Atom probe tomography\", Edgepedia (EdgeChat), https://www.edgepedia.org/atom-probe-tomography. Edgepedia Community License 1.0.", "credit_md": "\"[Atom probe tomography](https://www.edgepedia.org/atom-probe-tomography)\", Edgepedia (EdgeChat), [https://www.edgepedia.org/atom-probe-tomography](https://www.edgepedia.org/atom-probe-tomography). [Edgepedia Community License 1.0](https://www.edgepedia.org/edgepedia/license).", "credit_html": "\"Atom probe tomography\", Edgepedia (EdgeChat), https://www.edgepedia.org/atom-probe-tomography. Edgepedia Community License 1.0.", "speakable": "Atom probe tomography is an analytical microscopy technique that maps the 3D positions and elemental identities of individual atoms in a needle-shaped specimen, with sub-nanometer resolution and parts-per-million sensitivity." }