{ "id": "ep6jfmqf61", "slug": "bone-lengthening", "title": "Bone lengthening", "updated": "2026-10-25", "topic_path": [ { "id": "life", "label": "Life and health", "api_url": "https://www.edgepedia.org/api/v1/topics/life" }, { "id": "life.health", "label": "Human health and medicine", "api_url": "https://www.edgepedia.org/api/v1/topics/life.health" }, { "id": "life.health.clinical", "label": "Clinical assessment and procedures", "api_url": "https://www.edgepedia.org/api/v1/topics/life.health.clinical" }, { "id": "life.health.clinical.clinical-surgery", "label": "Surgery and surgical specialties", "api_url": "https://www.edgepedia.org/api/v1/topics/life.health.clinical.clinical-surgery" }, { "id": "life.health.clinical.clinical-surgery.orthopedic-surgery-procedures", "label": "Orthopedic surgery procedures", "api_url": "https://www.edgepedia.org/api/v1/topics/life.health.clinical.clinical-surgery.orthopedic-surgery-procedures" }, { "id": "life.health.clinical.clinical-surgery.orthopedic-surgery-procedures.bone-lengthening-and-limb-reconstruction", "label": "Bone lengthening and limb reconstruction", "api_url": "https://www.edgepedia.org/api/v1/topics/life.health.clinical.clinical-surgery.orthopedic-surgery-procedures.bone-lengthening-and-limb-reconstruction" } ], "geo": [ { "id": "geo.nongeo.t1946.life.health.clinical.clinical-surgery.orthopedic-surgery-procedures", "label": "Non-geographic · 1946 to 2000: Orthopedic surgery procedures", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo.t1946.life.health.clinical.clinical-surgery.orthopedic-surgery-procedures", "path": [ { "id": "geo.nongeo", "label": "Non-geographic", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo" }, { "id": "geo.nongeo.t1946", "label": "Non-geographic · 1946 to 2000", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo.t1946" }, { "id": "geo.nongeo.t1946.life", "label": "Life and health", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo.t1946.life" }, { "id": "geo.nongeo.t1946.life.health", "label": "Human health and medicine", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo.t1946.life.health" }, { "id": "geo.nongeo.t1946.life.health.clinical", "label": "Clinical assessment and procedures", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo.t1946.life.health.clinical" }, { "id": "geo.nongeo.t1946.life.health.clinical.clinical-surgery", "label": "Surgery and surgical specialties", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo.t1946.life.health.clinical.clinical-surgery" }, { "id": "geo.nongeo.t1946.life.health.clinical.clinical-surgery.orthopedic-surgery-procedures", "label": "Orthopedic surgery procedures", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.nongeo.t1946.life.health.clinical.clinical-surgery.orthopedic-surgery-procedures" } ] } ], "excerpt": "Bone lengthening is a surgical orthopedic technique that gradually lengthens a bone by cutting it and slowly pulling the segments apart, allowing new bone to form in the gap.", "snippet": "Bone lengthening is a surgical orthopedic technique that gradually lengthens a bone by cutting it and slowly pulling the segments apart, allowing new bone to form in the gap.", "node": "life.health.clinical.clinical-surgery.orthopedic-surgery-procedures.bone-lengthening-and-limb-reconstruction", "markdown": "# Bone lengthening\n\nBone lengthening is a surgical orthopedic technique that gradually lengthens a bone by cutting it and slowly pulling the segments apart, allowing new bone to form in the gap; it is used to treat limb length discrepancy, short stature, and segmental bone loss. The three clinical phases are latency, distraction, and consolidation, beginning with a corticotomy that resembles a closed low-energy fracture.[1](https://link.springer.com/article/10.1186/s10195-019-0541-3) Treatment courses typically span 6 to 18 months including distraction, consolidation, and rehabilitation.[2](https://www.ovid.com/jnls/jllr/fulltext/10.4103/jllr.jllr_1_26~prevention-of-complications-in-limb-lengthening-surgery)\n\n| Key fact | Detail |\n|---|---|\n| Standard distraction protocol | 1 mm/day divided into four 0.25 mm increments[3](https://pmc.ncbi.nlm.nih.gov/articles/PMC3364349/) |\n| Latency period | 3–10 days; typically 5–7 days for femur, 10–14 days for tibia[3](https://pmc.ncbi.nlm.nih.gov/articles/PMC3364349/) • [4](https://journals.lww.com/techortho/fulltext/2020/09000/principles_of_motorized_internal_lengthening_of.3.aspx) |\n| Healing (consolidation) index | About 1 month/cm in children, 2–3 months/cm in adults; 24.5–41.0 days/cm with magnetic nails depending on segment[3](https://pmc.ncbi.nlm.nih.gov/articles/PMC3364349/) • [5](https://www.ovid.com/jnls/jaaosglobal/fulltext/10.5435/jaaosglobal-d-25-00118~bone-healing-index-and-complications-of-a-magnetic-internal) |\n| Typical gain with magnetic nails | Mean 48.20 mm in a 23-patient PRECICE series[6](https://journals.sagepub.com/doi/10.1177/1602400321) |\n| Complication burden | 53% of patients in a 314-segment magnetic-nail cohort[7](https://actaorthop.org/actao/article/view/8479) • [5](https://www.ovid.com/jnls/jaaosglobal/fulltext/10.5435/jaaosglobal-d-25-00118~bone-healing-index-and-complications-of-a-magnetic-internal) |\n| Practical length limit | Most authors accept about 7–8 cm per procedure in the femur and 6–7 cm in the lower leg[8](https://pmc.ncbi.nlm.nih.gov/articles/PMC5145830/) |\n\n## How it works\n\nThe method rests on distraction osteogenesis, Ilizarov's law of tension-stress, which holds that living tissue subjected to slow, steady traction becomes metabolically activated in biosynthetic and proliferative pathways.[9](https://www.ovid.com/jnls/bhjd/fulltext/01745195-201371010-00011~the-evolution-of-the-ilizarov-technique-part-1-the-history) The latency phase, between osteotomy and the start of distraction, is biologically identical to the inflammatory phase of fracture repair: interleukins and platelet-derived growth factors attract mesenchymal stem cells and differentiate them into osteoblasts.[8](https://pmc.ncbi.nlm.nih.gov/articles/PMC5145830/)\n\nDuring distraction the process departs from fracture healing. Intramembranous bone formation predominates, and the gap organizes into five distinctive zones, with unmineralized bone centrally and mineralizing bone between.[8](https://pmc.ncbi.nlm.nih.gov/articles/PMC5145830/) New bone formation is detectable within one week of starting distraction; dual-energy X-ray absorptiometry in ten lengthened segments showed mineral accretion of 16 ± 1.86% per month in the tibia versus 11 ± 1.1% per month in the femur.[10](https://boneandjoint.org.uk/doi/10.1302/0301-620X.75B1.8421047) Blood flow at the distraction site rises to as much as ten times control values, peaking two weeks after distraction begins.[11](https://www.sciencedirect.com/science/article/pii/S2590093521000217)\n\n## How it is done\n\n1. **Corticotomy.** The bone is cut with a corticotomy that resembles a closed low-energy fracture.[1](https://link.springer.com/article/10.1186/s10195-019-0541-3)\n2. **Latency.** Distraction is delayed to allow early callus formation, classically 3–10 days depending on age, site, underlying disease, and drugs such as NSAIDs or steroids; in motorized-nail practice, 5–7 days for the femur and 10–14 days for the tibia.[3](https://pmc.ncbi.nlm.nih.gov/articles/PMC3364349/) • [8](https://pmc.ncbi.nlm.nih.gov/articles/PMC5145830/) • [4](https://journals.lww.com/techortho/fulltext/2020/09000/principles_of_motorized_internal_lengthening_of.3.aspx)\n3. **Distraction.** The classic rate is 1 mm/day divided into four 0.25 mm increments; smaller increments produce better bone formation.[3](https://pmc.ncbi.nlm.nih.gov/articles/PMC3364349/) • [8](https://pmc.ncbi.nlm.nih.gov/articles/PMC5145830/) Rates above 1 mm/day significantly increase nerve injury risk.[2](https://www.ovid.com/jnls/jllr/fulltext/10.4103/jllr.jllr_1_26~prevention-of-complications-in-limb-lengthening-surgery)\n4. **Consolidation and device removal.** The regenerate is monitored until bridging callus at least 2 mm thick appears in three of four cortices on anteroposterior and lateral radiographs, one of the radiological standards for fixator removal.[3](https://pmc.ncbi.nlm.nih.gov/articles/PMC3364349/)\n\n## Origin\n\n[Skeletal traction](https://www.edgepedia.org/skeletal-traction) for bone lengthening was applied using acute forced lengthening under narcotics for short distances and continuous calcaneal-pin traction of 25–30 kg after oblique osteotomy for larger ones.[1](https://link.springer.com/article/10.1186/s10195-019-0541-3) His reports appeared in the Italian literature in 1903 and in English in 1905; in 1905 he presented 26 patients, all achieving the desired 3 to 8 cm of lengthening, with severe nerve lesions and skin complications among the adverse events.[9](https://www.ovid.com/jnls/bhjd/fulltext/01745195-201371010-00011~the-evolution-of-the-ilizarov-technique-part-1-the-history) Gradual femoral lengthening with an external fixator gained 4 cm, and Abbot reported 73 lengthenings in 1932 with an average rate of 1.6 mm/day and the first described waiting period before distraction.[3](https://pmc.ncbi.nlm.nih.gov/articles/PMC3364349/) • [1](https://link.springer.com/article/10.1186/s10195-019-0541-3)\n\nGavriil Ilizarov began in 1951, treating a bone defect caused by tuberculosis with a circular frame and tensioned transfixation wires.[9](https://www.ovid.com/jnls/bhjd/fulltext/01745195-201371010-00011~the-evolution-of-the-ilizarov-technique-part-1-the-history) He achieved lower-extremity lengthenings of up to 25 cm in the early 1960s and gained wide recognition in 1967 by treating the Olympic high jumper Valeriy Brumel; The method was exposed to the West.[3](https://pmc.ncbi.nlm.nih.gov/articles/PMC3364349/) Ilizarov's tension-stress work was published in *Clinical Orthopaedics and Related Research* in 1989,[12](https://doi.org/10.1097/00003086-198901000-00038) and Dror Paley published a classification of problems, obstacles, and complications of the [Ilizarov technique](https://www.edgepedia.org/ilizarov-technique) in 1990.[13](https://doi.org/10.1097/00003086-199001000-00011)\n\n## Variants\n\n[External fixation](https://www.edgepedia.org/external-fixation) remains the reference approach: the Ilizarov ring frame, the monolateral fixator, and the Taylor Spatial Frame, a hexapodal computer-assisted circular frame of two rings and six struts that improved the accuracy of lengthening and multi-plane deformity correction.[1](https://link.springer.com/article/10.1186/s10195-019-0541-3) • [3](https://pmc.ncbi.nlm.nih.gov/articles/PMC3364349/) Its main burden is pin-site care and pin-site infection, reported at 10% to 60% depending on definitions and protocols.[2](https://www.ovid.com/jnls/jllr/fulltext/10.4103/jllr.jllr_1_26~prevention-of-complications-in-limb-lengthening-surgery)\n\nInternal devices avoid pins. Lengthening over nail (LON) combines a limited external frame with an intramedullary nail; a meta-analysis of 354 limbs found LON superior to conventional Ilizarov on external fixation index and consolidation index with no difference in length gained.[14](https://www.ncbi.nlm.nih.gov/books/NBK526298/)\n\nFully implantable nails followed. Rainer Baumgart, Augustin Betz, and Leonhard Schweiberer reported a fully implantable motorized intramedullary nail for lengthening and bone transport in 1997 (FitBone), powered through a subcutaneous antenna,[15](https://doi.org/10.1097/00003086-199710000-00023) and Baumgart described the reverse planning method for straight lengthening nails in 2009.[16](https://doi.org/10.1007/s00064-009-1709-4) The ratchet-driven Albizzia nail and the ISKD, cleared in the United States in 2001, were withdrawn or limited after high complication rates from uncontrolled distraction.[1](https://link.springer.com/article/10.1186/s10195-019-0541-3) The PRECICE nail, a titanium telescopic magnet-driven implant lengthened by an external remote controller, is now widely used alongside FitBone; the stainless-steel STRYDE variant was voluntarily withdrawn by NuVasive in February 2021 after reports of pain and bony abnormalities at the telescoping interface and is no longer available.[4](https://journals.lww.com/techortho/fulltext/2020/09000/principles_of_motorized_internal_lengthening_of.3.aspx) A meta-analysis of over 200 limbs found internal lengthening reduced the bone healing index by 13.7 days/cm compared with external fixation or LON.[5](https://www.ovid.com/jnls/jaaosglobal/fulltext/10.5435/jaaosglobal-d-25-00118~bone-healing-index-and-complications-of-a-magnetic-internal)\n\n## Applications\n\nIn 23 patients (mean age 23.6 years) lengthened with PRECICE nails, mean lengthening was 48.20 mm, mean consolidation index 1.12 months/cm, and mean time to full weight-bearing 5.15 months.[6](https://journals.sagepub.com/doi/10.1177/1602400321) Across 286 PRECICE lengthenings, the bone healing index was 24.5 ± 9.5 days/cm for antegrade femur, 33.5 ± 14.5 days/cm for retrograde femur, and 41.0 ± 17.4 days/cm for antegrade tibia.[5](https://www.ovid.com/jnls/jaaosglobal/fulltext/10.5435/jaaosglobal-d-25-00118~bone-healing-index-and-complications-of-a-magnetic-internal)\n\nIn achondroplasia, a meta-analysis of 14 studies and 1,149 patients found mean gains of 8.85 cm femoral, 7.36 cm tibial, and 8.38 cm humeral, with a fixator index of 37.1 days/cm and mean fixation duration of 7.71 months; reaching low-normal adult height requires about 30–40 cm of total gain over multiple stages.[17](https://link.springer.com/article/10.1007/s00264-025-06720-z)\n\n## Limitations and alternatives\n\nComplications are frequent. In a multicenter cohort of 314 magnetic-nail lengthenings in 257 patients, 53% of patients had a complication, most often device-related (0.3 per segment) or joint-related (0.2 per segment), with higher risk in the tibia and in patients over 30.[7](https://actaorthop.org/actao/article/view/8479) In the 286-event PRECICE series, 13.6% required another operation.[5](https://www.ovid.com/jnls/jaaosglobal/fulltext/10.5435/jaaosglobal-d-25-00118~bone-healing-index-and-complications-of-a-magnetic-internal) In Ilizarov bone transport, the most common major complications are joint stiffness (37.58%), delayed docking-site union (19.46%), axial deviation (18.79%), re-fracture (8.05%), and muscle contracture (6.04%).[18](https://www.ecios.org/DOIx.php?id=10.4055%2Fcios25045) Pin-site infection is the most common external-fixation complication.[2](https://www.ovid.com/jnls/jllr/fulltext/10.4103/jllr.jllr_1_26~prevention-of-complications-in-limb-lengthening-surgery)\n\nMost authors accept about 7–8 cm in the femur and 6–7 cm in the lower leg per lengthening, with no known absolute biological restraint.[8](https://pmc.ncbi.nlm.nih.gov/articles/PMC5145830/) Fracture risk after fixator removal rises when lengthening exceeds 15% of the initial segment length (except in achondroplasia) and when latency was under 7 days,[8](https://pmc.ncbi.nlm.nih.gov/articles/PMC5145830/) and joint contracture risk rises beyond 20% of original segment length.[2](https://www.ovid.com/jnls/jllr/fulltext/10.4103/jllr.jllr_1_26~prevention-of-complications-in-limb-lengthening-surgery)\n\nFor leg-length discrepancy in skeletally immature patients, temporary [epiphysiodesis](https://www.edgepedia.org/epiphysiodesis) (surgically stopping a bone's growth plate to limit growth) is the main alternative: in a meta-analysis of 2,184 patients, success was 76% with percutaneous epiphysiodesis using screws, 67% with tension-band plates, and 51% with Blount staples, with severe complications in 7%, 17%, and 16% respectively.[19](https://actaorthop.org/actao/article/view/41104) For metaphyseal defects, shortening and in situ relengthening needed fewer operations than bone transport (2.0 vs 3.0) but is recommended only for defects of 8 cm or less.[20](https://boneandjoint.org.uk/Article/10.1302/0301-620X.107B12.BJJ-2024-0882.R2)\n\n## References\n\n1. [Limb lengthening history, evolution, complications and current concepts (Journal of Orthopaedics and Traumatology, 2019)](https://link.springer.com/article/10.1186/s10195-019-0541-3)\n2. [Prevention of Complications in Limb Lengthening Surgery (Journal of Limb Lengthening & Reconstruction)](https://www.ovid.com/jnls/jllr/fulltext/10.4103/jllr.jllr_1_26~prevention-of-complications-in-limb-lengthening-surgery)\n3. [Current concepts of leg lengthening (Journal of Children's Orthopaedics, 2012)](https://pmc.ncbi.nlm.nih.gov/articles/PMC3364349/)\n4. [Principles of Motorized Internal Lengthening of Long Bones (Techniques in Orthopaedics)](https://journals.lww.com/techortho/fulltext/2020/09000/principles_of_motorized_internal_lengthening_of.3.aspx)\n5. [Bone Healing Index and Complications of a Magnetic Internal Lengthening Nail: A Retrospective Series of 286 Bone Lengthening Events (JAAOS Global, 2025)](https://www.ovid.com/jnls/jaaosglobal/fulltext/10.5435/jaaosglobal-d-25-00118~bone-healing-index-and-complications-of-a-magnetic-internal)\n6. [Use of a Magnetic Bone Nail for Lengthening of the Femur and Tibia](https://journals.sagepub.com/doi/10.1177/1602400321)\n7. [Complications and risk factors of intramedullary bone lengthening nails: a retrospective multicenter cohort study of 314 FITBONE and PRECICE nails (Acta Orthopaedica)](https://actaorthop.org/actao/article/view/8479)\n8. [The biology of bone lengthening (Strategies in Trauma and Limb Reconstruction / PMC)](https://pmc.ncbi.nlm.nih.gov/articles/PMC5145830/)\n9. [The Evolution of the Ilizarov Technique, Part 1: The History (Bulletin of the Hospital for Joint Diseases, 2013)](https://www.ovid.com/jnls/bhjd/fulltext/01745195-201371010-00011~the-evolution-of-the-ilizarov-technique-part-1-the-history)\n10. [New bone formation during leg lengthening evaluated by dual energy X-ray absorptiometry (J Bone Joint Surg Br, 1993)](https://boneandjoint.org.uk/doi/10.1302/0301-620X.75B1.8421047)\n11. [Mechanical regulation of bone regeneration during distraction osteogenesis (review)](https://www.sciencedirect.com/science/article/pii/S2590093521000217)\n12. [GAVRIIL A. ILIZAROV (1989). The Tension-Stress Effect on the Genesis and Growth of Tissues. Clinical Orthopaedics and Related Research.](https://doi.org/10.1097/00003086-198901000-00038)\n13. [DROR PALEY (1990). Problems, Obstacles, and Complications of Limb Lengthening by the Ilizarov Technique. Clinical Orthopaedics and Related Research.](https://doi.org/10.1097/00003086-199001000-00011)\n14. [PRECICE Intramedullary Limb Lengthening System: A Review of Clinical Effectiveness (NCBI Bookshelf health technology assessment)](https://www.ncbi.nlm.nih.gov/books/NBK526298/)\n15. [Rainer Baumgart, Augustin Betz, Leonhard Schweiberer (1997). A Fully Implantable Motorized Intramedullary Nail for Limb Lengthening and Bone Transport. Clinical Orthopaedics and Related Research.](https://doi.org/10.1097/00003086-199710000-00023)\n16. [Rainer Baumgart (2009). The Reverse Planning Method for Lengthening of the Lower Limb Using a Straight Intramedullary Nail with or without Deformity Correction. Operative Orthopädie und Traumatologie.](https://doi.org/10.1007/s00064-009-1709-4)\n17. [Efficacy and safety of limb lengthening in achondroplasia: A systematic review and meta-analysis (International Orthopaedics, 2025)](https://link.springer.com/article/10.1007/s00264-025-06720-z)\n18. [Asymmetric distraction osteogenesis in the tibia (Clinics in Orthopedic Surgery)](https://www.ecios.org/DOIx.php?id=10.4055%2Fcios25045)\n19. [Staples, tension-band plates, and percutaneous epiphysiodesis screws used for leg-length discrepancy treatment: a systematic review and proportional meta-analysis (Acta Orthopaedica)](https://actaorthop.org/actao/article/view/41104)\n20. [Shortening and in situ relengthening versus bone transport for the treatment of metaphyseal defect of lower limb long bones (Bone & Joint Journal, 2024/2025)](https://boneandjoint.org.uk/Article/10.1302/0301-620X.107B12.BJJ-2024-0882.R2)\n\n---\n*Topic: Encyclopedia › Life and health › Human health and medicine › Clinical assessment and procedures › Surgery and surgical specialties › Orthopedic surgery procedures › Bone lengthening and limb reconstruction*\n\n*Initially written Sep 29, 2026 · Edited: Oct 15, 2026; Oct 25, 2026*\n\n*Copyright 2026 EdgeChat AI, a subsidiary of Biostate AI.*\n\nLicense: Edgepedia Community License 1.0, https://www.edgepedia.org/edgepedia/license\n", "same_as": [], "url": "https://www.edgepedia.org/bone-lengthening", "markdown_url": "https://www.edgepedia.org/bone-lengthening.md", "license": { "name": "Edgepedia Community License 1.0", "url": "https://www.edgepedia.org/edgepedia/license", "summary": "Free with credit, commercial use included. AI training is open to everyone. For other uses, organizations over USD 100M in revenue or 100M monthly users license separately.", "spdx": "LicenseRef-Edgepedia-Community-1.0" }, "credit": "\"Bone lengthening\", Edgepedia (EdgeChat), https://www.edgepedia.org/bone-lengthening. Edgepedia Community License 1.0.", "credit_md": "\"[Bone lengthening](https://www.edgepedia.org/bone-lengthening)\", Edgepedia (EdgeChat), [https://www.edgepedia.org/bone-lengthening](https://www.edgepedia.org/bone-lengthening). [Edgepedia Community License 1.0](https://www.edgepedia.org/edgepedia/license).", "credit_html": "\"Bone lengthening\", Edgepedia (EdgeChat), https://www.edgepedia.org/bone-lengthening. Edgepedia Community License 1.0.", "speakable": "Bone lengthening is a surgical orthopedic technique that gradually lengthens a bone by cutting it and slowly pulling the segments apart, allowing new bone to form in the gap." }