{ "id": "ep8xtxycby", "slug": "eric-bakker", "title": "Eric Bakker", "updated": "2026-10-15", "topic_path": [ { "id": "physical", "label": "Physical world and mathematics", "api_url": "https://www.edgepedia.org/api/v1/topics/physical" }, { "id": "physical.scientists", "label": "Physical and mathematical scientists", "api_url": "https://www.edgepedia.org/api/v1/topics/physical.scientists" }, { "id": "physical.scientists.chemistry", "label": "Chemists", "api_url": "https://www.edgepedia.org/api/v1/topics/physical.scientists.chemistry" }, { "id": "physical.scientists.chemistry.chem-bio", "label": "Researchers in chemical biology, analytical chemistry, and mass spectrometry", "api_url": "https://www.edgepedia.org/api/v1/topics/physical.scientists.chemistry.chem-bio" }, { "id": "physical.scientists.chemistry.chem-bio.bioanalytical-method-development-and-separation-science-lc-m", "label": "Bioanalytical method development and separation science (LC-MS/MS)", "api_url": "https://www.edgepedia.org/api/v1/topics/physical.scientists.chemistry.chem-bio.bioanalytical-method-development-and-separation-science-lc-m" } ], "geo": [ { "id": "geo.weu.t1946.physical.scientists.chemistry", "label": "Western Europe · 1946 to 2000: Chemists", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.weu.t1946.physical.scientists.chemistry", "path": [ { "id": "geo.weu", "label": "Western Europe", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.weu" }, { "id": "geo.weu.t1946", "label": "Western Europe · 1946 to 2000", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.weu.t1946" }, { "id": "geo.weu.t1946.physical", "label": "Physical world and mathematics", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.weu.t1946.physical" }, { "id": "geo.weu.t1946.physical.scientists", "label": "Physical and mathematical scientists", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.weu.t1946.physical.scientists" }, { "id": "geo.weu.t1946.physical.scientists.chemistry", "label": "Chemists", "api_url": "https://www.edgepedia.org/api/v1/geo/geo.weu.t1946.physical.scientists.chemistry" } ] } ], "excerpt": "Eric Bakker is a Swiss analytical chemist who has held the chair of analytical chemistry at the University of Geneva since 2010, known for ion-selective electrodes and bulk optodes.", "snippet": "Eric Bakker is a Swiss analytical chemist who has held the chair of analytical chemistry at the University of Geneva since 2010, known for ion-selective electrodes and bulk optodes.", "node": "physical.scientists.chemistry.chem-bio.bioanalytical-method-development-and-separation-science-lc-m", "markdown": "# Eric Bakker\n\n**Eric Bakker** (born in Switzerland into a Dutch family) is a Swiss-based analytical chemist who has held the chair of analytical chemistry at the University of Geneva since 2010.[1](https://doi.org/10.2533/chimia.2020.569) • [2](https://doi.org/10.2533/chimia.2025.7) He is known for work on carrier-based ion-selective electrodes and bulk optodes, chemical sensors that measure ion concentrations in blood, water, and other samples, and for reshaping the theory and practice of how such sensors are calibrated and read out.[3](https://www.ericbakkergroup.ch/EricBakker.html)\n\n| Fact | Detail |\n|---|---|\n| Field | Analytical chemistry: ion-selective electrodes, bulk optodes, electroanalysis |\n| Current post | Chair of Analytical Chemistry, University of Geneva, since 2010[2](https://doi.org/10.2533/chimia.2025.7) |\n| Training | Dipl. Chem. ETH (1985–1989); doctorate ETH Zurich, 1993, with Wilhelm Simon[4](https://orcid.org/0000-0001-8970-4343) |\n| Earlier posts | Auburn University 1995–2005; Purdue University 2005–2008; Curtin University 2007–2010[4](https://orcid.org/0000-0001-8970-4343) |\n| Signature work | \"Carrier-Based Ion-Selective Electrodes and Bulk Optodes. 1. General Characteristics\", *Chemical Reviews*, 1997[5](https://doi.org/10.1021/cr940394a) |\n| Awards | Talanta Medal 2025; ISE Fellow 2024; Charles N. Reilley Award 2024; Simon Widmer Award 2019[3](https://www.ericbakkergroup.ch/EricBakker.html) |\n| Editorial role | Executive Editor of *ACS Sensors*[1](https://doi.org/10.2533/chimia.2020.569) |\n\n## Early life and training\n\nBakker spent his childhood in both the French-speaking and German-speaking parts of Switzerland. He studied chemistry at [ETH Zurich](https://www.edgepedia.org/eth-zurich), earning the Dipl. Chem. ETH between 1985 and 1989, and completed his doctorate there between 1990 and 1993 with Wilhelm Simon, working on optical sensors.[1](https://doi.org/10.2533/chimia.2020.569) • [4](https://orcid.org/0000-0001-8970-4343)\n\nHe then moved to the University of Michigan for parallel postdoctoral appointments with [Mark Meyerhoff](https://www.edgepedia.org/mark-e-meyerhoff) and [Raoul Kopelman](https://www.edgepedia.org/raoul-kopelman), from August 1993 to June 1995.[1](https://doi.org/10.2533/chimia.2020.569) • [4](https://orcid.org/0000-0001-8970-4343)\n\n## Career\n\nIn 2005 he became professor at [Purdue University](https://www.edgepedia.org/purdue-university) in West Lafayette, a post his ORCID record dates from 16 August 2005 to 15 August 2008.[4](https://orcid.org/0000-0001-8970-4343) In 2007 he moved to [Curtin University](https://www.edgepedia.org/curtin-university) in Perth as Professor and Director of the Nanochemistry Research Institute, a role he held until 31 May 2010.[4](https://orcid.org/0000-0001-8970-4343)\n\nSince 1 June 2010 he has been Professor in the Department of Inorganic and Analytical Chemistry at the University of Geneva, where he also served as Director of the department.[4](https://orcid.org/0000-0001-8970-4343) • [6](https://scg.ch/scg-news/news-analytical/prof-eric-bakker-receives-the-simon-widmer-award-2019) His group there works on the physico-chemical principles of sensing, materials fabrication, and electrochemical sensors deployed in aquatic systems and hospitals.[7](https://www.unige.ch/sciences/chimie/news/prof-bakker-talanta-2025)\n\n## Research: carrier-based ion-selective electrodes and bulk optodes\n\nAn ion-selective electrode (ISE) converts the activity of a specific ion in solution into an electrical potential across a membrane that preferentially binds that ion. In carrier-based ISEs the membrane is a solvent polymeric film doped with an ionophore, a molecule engineered to bind the target ion selectively. Bulk optodes use the same extraction chemistry but transduce the ion binding optically, through a chromoionophore whose color changes with ion concentration, so the readout can be a spectrometer, a camera, or the human eye.[5](https://doi.org/10.1021/cr940394a) • [8](https://pubs.rsc.org/en/content/articlehtml/2022/cc/d1cc06636f) Ion-selective optodes had accumulated 10,578 publications in the Web of Science Core Collection as of 2022.[8](https://pubs.rsc.org/en/content/articlehtml/2022/cc/d1cc06636f)\n\nTwo problems defined much of his research agenda. First, selectivity: the traditional separate-solution and fixed-interference methods for measuring how well a membrane discriminates against interfering ions were still those proposed by IUPAC in 1976, and they carry biases such as primary-ion leaching and counterion interference. His 2000 *Analytical Chemistry* review related selectivities quantitatively to equilibria at the sample–membrane interface and presented a recipe for determining selectivity coefficients unaffected by those biases.[9](https://doi.org/10.1021/ac991146n) Second, detection limits: work by Sokalski in Ernö Pretsch's group added EDTA to the inner solution of a lead-selective membrane, showing that ultra-low detection limits were attainable and starting a broad effort to lower them.[1](https://doi.org/10.2533/chimia.2020.569) By 2007, lower detection limits and selectivity coefficients had improved in many cases by factors of up to 106 and 1010 respectively, opening environmental trace analysis and potentiometric biosensing.[10](https://pmc.ncbi.nlm.nih.gov/articles/PMC2515866/)\n\nHis group's own contributions include pulstrodes, in which an applied current pulse is followed by measurement at zero current so that ohmic drop is eliminated, and chronopotentiometric readout that reports total available concentration, including labile complexes, for speciation analysis.[1](https://doi.org/10.2533/chimia.2020.569) On the optical side, ionophore-based optodes were miniaturized from spin-coated films to microparticles and then to the nanoscale, with lower concentration limits sometimes in the nano- to picomolar range.[1](https://doi.org/10.2533/chimia.2020.569) The two transduction modes trade off differently: chromoionophore-based lead optodes can reach lower detection limits than equivalent ISEs, but response times can exceed 50 hours at very low concentrations in EDTA buffer.[8](https://pubs.rsc.org/en/content/articlehtml/2022/cc/d1cc06636f) A hyperpolarization-based indirect transduction mechanism allowed protamine to be determined in serum and plasma with no detectable interference from small ions.[8](https://pubs.rsc.org/en/content/articlehtml/2022/cc/d1cc06636f)\n\nThe group has also moved sensing out of the laboratory: it co-developed submersible potentiometric probes within a European project and deployed them in the Arcachon Bay in France for in situ monitoring of aquatic systems.[1](https://doi.org/10.2533/chimia.2020.569)\n\n## Representative work\n\nThe 1997 *Chemical Reviews* paper \"Carrier-Based Ion-Selective Electrodes and Bulk Optodes. 1. General Characteristics\", written at [Auburn University](https://www.edgepedia.org/auburn-university), set out the general characteristics of both sensor families in one reference work; the publisher page records about 2,000 citations.[5](https://doi.org/10.1021/cr940394a) According to *Selectivity of Potentiometric Ion Sensors* (*Analytical Chemistry*, 2000), its companion review established the modern treatment of potentiometric selectivity described above.[9](https://doi.org/10.1021/ac991146n) His 2002 *Analytical Chemistry* review \"Electrochemical Sensors\" surveyed the field of electrochemical sensing.[11](https://doi.org/10.1021/ac0202278)\n\n## Honors, professional roles and industry\n\nBakker received the Roche Prize in 2004, the Robert Boyle Prize in 2014, the Simon Widmer Award 2019 from the Swiss Chemical Society for his pioneering work in ion-selective electrochemical and optical sensors, the Charles N. Reilley Award and ISE Fellowship in 2024, and the Talanta Medal 2025, a biennial award for outstanding achievements in analytical chemistry, recognizing his work in electrochemistry, electrochemical methodology, electrochemical materials, and environmental electrochemistry.[3](https://www.ericbakkergroup.ch/EricBakker.html) • [6](https://scg.ch/scg-news/news-analytical/prof-eric-bakker-receives-the-simon-widmer-award-2019) • [7](https://www.unige.ch/sciences/chimie/news/prof-bakker-talanta-2025)\n\nHe became Executive Editor of *ACS Sensors*[1](https://doi.org/10.2533/chimia.2020.569) and served as President of the Division of Analytical Sciences of the Swiss Chemical Society until 2023.[3](https://www.ericbakkergroup.ch/EricBakker.html) On the industry side, he acts as Scientific Advisor to Eaglenos; his group's funding comes from the University of Geneva, the Swiss National Science Foundation, the European Union, and private industry.[3](https://www.ericbakkergroup.ch/EricBakker.html) \n\n## Recent developments\n\nHis recent work centers on robustness and sensitivity in the field. A 2025 *Chimia* review argues for symmetry in potentiometric cell design to minimize the influence of temperature, explains self-powered sensing systems that no longer require a battery, and connects these to protocols for improving sensitivity beyond the Nernst limit of 59.2 mV/z.[2](https://doi.org/10.2533/chimia.2025.7) Constant-potential coulometry with a [voltage follower](https://www.edgepedia.org/voltage-follower) was demonstrated with an oceanographic pH electrode, giving a precision of 6 µpH for pH increments of 0.01 units.[2](https://doi.org/10.2533/chimia.2025.7) Group papers from 2024 to 2026 extend these lines: a submersible probe coupling a symmetrical pH cell to constant-potential coulometry (*ACS Meas. Sci. Au*, 2026), zero-current [chronopotentiometry](https://www.edgepedia.org/chronopotentiometry) for glucose biosensors (*Microchim. Acta*, 2026), ionophores for reference electrodes based on organic electrolytes (*Anal. Chem.*, 2025), spatially resolved ion sensing by voltammetric ion transfer microscopy (*JACS Au*, 2025), microfabricated self-referencing pulstrodes (*Sensors & Diagnostics*, 2025), and mass-production of ion-selective electrodes by spotting, where overall production and drying takes less than 30 minutes (*Sens. Actuators B*, 2025).[12](https://www.ericbakkergroup.ch/Publications.html) • [13](https://www.sciencedirect.com/author/7202451921/eric-j-bakker)\n\n## References\n\n1. A Scientific Journey with Ionophore-Based Sensors, *Chimia* 2020, 74, 569–576. https://doi.org/10.2533/chimia.2020.569\n2. Improving Robustness, Sensitivity and Simplicity of Potentiometric Sensors Through Symmetry and Conceptual Design, *Chimia* 2025. https://doi.org/10.2533/chimia.2025.7\n3. Eric Bakker, personal CV page, Bakker Group, University of Geneva. https://www.ericbakkergroup.ch/EricBakker.html\n4. Eric Bakker (0000-0001-8970-4343), ORCID. https://orcid.org/0000-0001-8970-4343\n5. Carrier-Based Ion-Selective Electrodes and Bulk Optodes. 1. General Characteristics, *Chemical Reviews* 1997, 97, 3083–3132. https://doi.org/10.1021/cr940394a\n6. Prof. Eric Bakker receives the Simon Widmer Award 2019, Swiss Chemical Society. https://scg.ch/scg-news/news-analytical/prof-eric-bakker-receives-the-simon-widmer-award-2019\n7. Prof. Bakker awarded the Talanta 2025 medal, University of Geneva. https://www.unige.ch/sciences/chimie/news/prof-bakker-talanta-2025\n8. Recent improvements to the selectivity of extraction-based optical ion sensors, *Chemical Communications* 2022. https://pubs.rsc.org/en/content/articlehtml/2022/cc/d1cc06636f\n9. Selectivity of Potentiometric Ion Sensors, *Analytical Chemistry* 2000. https://doi.org/10.1021/ac991146n\n10. Modern Potentiometry, 2007. https://pmc.ncbi.nlm.nih.gov/articles/PMC2515866/\n11. Electrochemical Sensors, *Analytical Chemistry* 2002. https://doi.org/10.1021/ac0202278\n12. Group Publications, Bakker Group, University of Geneva. https://www.ericbakkergroup.ch/Publications.html\n13. Eric J. Bakker author profile, ScienceDirect. https://www.sciencedirect.com/author/7202451921/eric-j-bakker\n\n---\n*Topic: Encyclopedia › Physical world and mathematics › Physical and mathematical scientists › Chemists › Researchers in chemical biology, analytical chemistry, and mass spectrometry › Bioanalytical method development and separation science (LC-MS/MS)*\n\n*Initially written Sep 21, 2026 · Reviewed: Sep 25, 2026; Sep 30, 2026 · Edited: Sep 25, 2026; Sep 30, 2026; Oct 11, 2026; Oct 15, 2026 · Last review: Sep 30, 2026*\n\n*Copyright 2026 EdgeChat AI, a subsidiary of Biostate AI.*\n\nLicense: Edgepedia Community License 1.0, https://www.edgepedia.org/edgepedia/license\n", "same_as": [ "https://orcid.org/0000-0001-8970-4343" ], "url": "https://www.edgepedia.org/eric-bakker", "markdown_url": "https://www.edgepedia.org/eric-bakker.md", "license": { "name": "Edgepedia Community License 1.0", "url": "https://www.edgepedia.org/edgepedia/license", "summary": "Free with credit, commercial use included. AI training is open to everyone. For other uses, organizations over USD 100M in revenue or 100M monthly users license separately.", "spdx": "LicenseRef-Edgepedia-Community-1.0" }, "credit": "\"Eric Bakker\", Edgepedia (EdgeChat), https://www.edgepedia.org/eric-bakker. Edgepedia Community License 1.0.", "credit_md": "\"[Eric Bakker](https://www.edgepedia.org/eric-bakker)\", Edgepedia (EdgeChat), [https://www.edgepedia.org/eric-bakker](https://www.edgepedia.org/eric-bakker). [Edgepedia Community License 1.0](https://www.edgepedia.org/edgepedia/license).", "credit_html": "\"Eric Bakker\", Edgepedia (EdgeChat), https://www.edgepedia.org/eric-bakker. Edgepedia Community License 1.0.", "speakable": "Eric Bakker is a Swiss analytical chemist who has held the chair of analytical chemistry at the University of Geneva since 2010, known for ion-selective electrodes and bulk optodes." }