# Disease (Lady Gaga song)
**Disease** is a song by the American singer [Lady Gaga](https://www.edgepedia.org/lady-gaga), released on October 25, 2024 by [Interscope Records](https://www.edgepedia.org/interscope-records) as the lead single from her seventh studio album, later titled *[Mayhem](https://www.edgepedia.org/mayhem-lady-gaga-album)*.[1](https://music.apple.com/us/album/disease-single/1775468356) • [2](https://variety.com/2024/music/news/lady-gaga-disease-new-single-1236190293/) Written by Gaga, Michael Polansky, Andrew Watt, and Cirkut, and produced by Watt and Cirkut alongside Gaga, it is a dark, industrial-tinged dance-pop track about playing the doctor and curing a lover's disease.[3](https://www.youtube.com/watch?v=4qv16WcOCYA) • [2](https://variety.com/2024/music/news/lady-gaga-disease-new-single-1236190293/)
| Key fact | Detail |
|---|---|
| Release | October 25, 2024, one-song single on Interscope Records[1](https://music.apple.com/us/album/disease-single/1775468356) |
| Writers | Lady Gaga, Michael Polansky, Andrew Watt, and Cirkut (Henry Walter); Watt and Cirkut also produce[3](https://www.youtube.com/watch?v=4qv16WcOCYA) • [2](https://variety.com/2024/music/news/lady-gaga-disease-new-single-1236190293/) |
| Album placement | First single from Gaga's seventh studio album, dubbed LG7 in a press release and later titled *Mayhem*[4](https://www.rollingstone.com/music/music-news/lady-gaga-disease-new-song-1235142869/) • [5](https://music.apple.com/us/song/disease/1792666999) |
| Sound | Maximalist dance-pop with a cavernous synth line against industrial drums and a shout-along chorus; synths compared to Nine Inch Nails and Gaga's *The Fame Monster* era[4](https://www.rollingstone.com/music/music-news/lady-gaga-disease-new-song-1235142869/) • [6](https://www.officialcharts.com/songs/lady-gaga-disease-0/) |
| UK chart peak | Number 7 on the Official Singles Chart on 07/11/2024; 18 weeks in the Top 100 across two runs[6](https://www.officialcharts.com/songs/lady-gaga-disease-0/) |
| Runtime | 3:49 on Spotify and 3:50 on the official YouTube upload; BBC Culture cites 3 minutes 51 seconds[7](https://open.spotify.com/track/1P7uBwJNWttdhskuPtTs4v) • [3](https://www.youtube.com/watch?v=4qv16WcOCYA) • [8](https://www.bbc.com/culture/article/20241025-disease-why-lady-gagas-comeback-hits-the-spot) |
| Streaming | About 359.7 million Spotify streams as of retrieval; included on *NOW That's What I Call Music! 120* (2025)[7](https://open.spotify.com/track/1P7uBwJNWttdhskuPtTs4v) |
## Background and release
Gaga teased her seventh studio album in July 2024 and confirmed it in September, ahead of the premiere of *Joker: Folie à Deux*; a press release gave spring 2025 as the album's due date.[2](https://variety.com/2024/music/news/lady-gaga-disease-new-single-1236190293/) "Disease" arrived on October 25, 2024 as a one-song pop single on Interscope.[1](https://music.apple.com/us/album/disease-single/1775468356) It followed her duet with [Bruno Mars](https://www.edgepedia.org/bruno-mars), "Die with a Smile", which at the time was dominating the [Billboard Global 200](https://www.edgepedia.org/billboard-global-200) as one of 2024's longest-running number ones.[2](https://variety.com/2024/music/news/lady-gaga-disease-new-single-1236190293/) Gaga's previous full-length album had been 2020's *Chromatica*, her sixth number one on the [Billboard](https://www.edgepedia.org/billboard-magazine) 200.[2](https://variety.com/2024/music/news/lady-gaga-disease-new-single-1236190293/)
## Writing and production
The official credits list Lady Gaga as composer, lyricist, producer, and vocalist; Andrew Watt as composer, lyricist, and producer; Cirkut (Henry Walter) as composer, lyricist, programmer, and producer; and [Michael Polansky](https://www.edgepedia.org/michael-polansky) as composer and lyricist.[3](https://www.youtube.com/watch?v=4qv16WcOCYA) Serban Ghenea mixed the track and Randy Merrill mastered it, with engineering by Paul LaMalfa, Bryce Bordone, and Marco Sonzini; the recording carries the ℗ 2024 Interscope Records line.[3](https://www.youtube.com/watch?v=4qv16WcOCYA)
Polansky, Gaga's fiancé, played a role in the album's direction. In a September 2024 *Vogue* cover interview, Gaga said he told her plainly: "Babe. I love you. You need to make pop music."[8](https://www.bbc.com/culture/article/20241025-disease-why-lady-gagas-comeback-hits-the-spot)
## Composition and lyrics
According to Rolling Stone, the song is maximalist pop built around a huge, echoing synth that builds and crashes into industrial-style percussion before bursting into a trademark Gaga chorus made for shouting along.[4](https://www.rollingstone.com/music/music-news/lady-gaga-disease-new-song-1235142869/) Official Charts points to cascading industrial-rock synths that recall [Nine Inch Nails](https://www.edgepedia.org/nine-inch-nails) as much as Gaga's *The Fame Monster* era.[6](https://www.officialcharts.com/songs/lady-gaga-disease-0/) BBC Culture notes that at three minutes and 51 seconds the song is unfashionably long for a pop single in the streaming era, and that it recalls the dark maximalist dance-pop of 2008's *The Fame Monster* and "Bad Romance".[8](https://www.bbc.com/culture/article/20241025-disease-why-lady-gagas-comeback-hits-the-spot)
Lyrically, the song is about curing a lover's tortured disease.[2](https://variety.com/2024/music/news/lady-gaga-disease-new-single-1236190293/) The chorus runs "I could play the doctor, I can cure your disease / If you were a sinner, I could make you believe".[4](https://www.rollingstone.com/music/music-news/lady-gaga-disease-new-song-1235142869/) BBC Culture also cites the line "I can smell your sickness, I can cure ya, cure your disease", reading the song as being about love's healing potential.[8](https://www.bbc.com/culture/article/20241025-disease-why-lady-gagas-comeback-hits-the-spot)
## Gaga's framing and the album context
In a September 2024 Rolling Stone interview, Gaga said the album was "nothing like" *Chromatica*, adding: "What I would say is, it's all for me. It's meant to be ingested as a time in my life."[4](https://www.rollingstone.com/music/music-news/lady-gaga-disease-new-song-1235142869/) She told *Vogue* that the album revisits an earlier period of her life "from a place of happiness instead of misery".[2](https://variety.com/2024/music/news/lady-gaga-disease-new-single-1236190293/) "Disease" appears on the album *Mayhem*, which Apple Music lists with multiple official music video versions of the song.[5](https://music.apple.com/us/song/disease/1792666999)
## Critical reception
The Guardian hailed "Disease" as a "return to form and to her classic sound", while The Independent called it Gaga's "best in a long while", with "a potent dose of dungeon-dark electro-pop".[8](https://www.bbc.com/culture/article/20241025-disease-why-lady-gagas-comeback-hits-the-spot) BBC Culture situated the song within a 2024 pop landscape shaped by [Chappell Roan](https://www.edgepedia.org/chappell-roan), Sabrina Carpenter, and [Charli XCX](https://www.edgepedia.org/charli-xcx), arguing that Gaga's pop maximalism fits rather than contradicts the moment.[8](https://www.bbc.com/culture/article/20241025-disease-why-lady-gagas-comeback-hits-the-spot)
## Commercial performance
On the UK Official Singles Chart, "Disease" debuted and peaked at number 7 on 07/11/2024, released on Interscope with catalog number USUM72407015.[6](https://www.officialcharts.com/songs/lady-gaga-disease-0/) It spent 18 weeks in the Top 100 across two chart runs, from 07/11/2024 to 26/12/2024 and from 09/01/2025 to 13/03/2025.[6](https://www.officialcharts.com/songs/lady-gaga-disease-0/) After debuting at 7, it fell to 12, 21, 29, 44, 71, 83, and 82 over its first eight weeks, then returned in January 2025 and re-peaked at number 48 on 20/02/2025.[6](https://www.officialcharts.com/songs/lady-gaga-disease-0/) Other UK surveys show peaks of 2, 19, 18, and 11, all on Interscope.[6](https://www.officialcharts.com/songs/lady-gaga-disease-0/) On Spotify the song had accumulated 359,724,369 streams as of retrieval and appears on the 2025 compilation *NOW That's What I Call Music! 120*.[7](https://open.spotify.com/track/1P7uBwJNWttdhskuPtTs4v)
## Music video
An official music video for "Disease" is hosted on Lady Gaga's official website, and Apple Music lists multiple official video versions of the song on *Mayhem*.[9](https://www.ladygaga.com/us-en/music/disease) • [5](https://music.apple.com/us/song/disease/1792666999)
## What changed since 2023: Disease and the Mayhem era
"Disease" opened the LG7 campaign in late 2024 while "Die with a Smile" still dominated the Billboard Global 200, giving Gaga two concurrent hits in different registers.[2](https://variety.com/2024/music/news/lady-gaga-disease-new-single-1236190293/) Its UK chart life ran in two phases: an eight-week autumn run that faded to number 82 by late December, and a ten-week return from January to March 2025 that carried it back to number 48.[6](https://www.officialcharts.com/songs/lady-gaga-disease-0/) By 2025 the song had been folded into the album *Mayhem* and the compilation *NOW That's What I Call Music! 120*, and Gaga's official site lists it alongside later 2025 releases such as "The Dead Dance".[5](https://music.apple.com/us/song/disease/1792666999) • [7](https://open.spotify.com/track/1P7uBwJNWttdhskuPtTs4v) • [9](https://www.ladygaga.com/us-en/music/disease)
## References
1. [Disease – Single, Apple Music](https://music.apple.com/us/album/disease-single/1775468356)
2. [Lady Gaga Shares New 'Disease' Single, Variety](https://variety.com/2024/music/news/lady-gaga-disease-new-single-1236190293/)
3. [Disease (official audio credits) – Lady Gaga Topic, YouTube](https://www.youtube.com/watch?v=4qv16WcOCYA)
4. [Lady Gaga 'Disease': Pop Star Drops New Song, Rolling Stone](https://www.rollingstone.com/music/music-news/lady-gaga-disease-new-song-1235142869/)
5. [Disease – Song, Apple Music](https://music.apple.com/us/song/disease/1792666999)
6. [DISEASE – LADY GAGA, Official Charts](https://www.officialcharts.com/songs/lady-gaga-disease-0/)
7. [Disease – Spotify](https://open.spotify.com/track/1P7uBwJNWttdhskuPtTs4v)
8. [Disease: Why Lady Gaga's comeback hits the spot, BBC Culture](https://www.bbc.com/culture/article/20241025-disease-why-lady-gagas-comeback-hits-the-spot)
9. [Disease, Lady Gaga official site](https://www.ladygaga.com/us-en/music/disease)
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*Topic: Encyclopedia › Arts and culture › Music › Musical works and recordings › Compositions and songs › Pop, rock, and metal songs › Pop songs › Pop songs of the 2020s › 2024 and 2025 songs › 2024 pop songs*
*Initially written Sep 17, 2026 · Reviewed: Oct 25, 2026 · Edited: Oct 15, 2026; Oct 25, 2026 · Last review: Oct 25, 2026*
*Copyright 2026 EdgeChat AI, a subsidiary of Biostate AI.*
License: Edgepedia Community License 1.0, https://www.edgepedia.org/edgepedia/license