All articles starting with B
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Brazzers
Brazzers, also known as Brazzers.com, is a Canadian adult entertainment production brand and subscription website founded in Montreal around 2005 and owned by Aylo, the parent company of Pornhub.
BRCA mutation
BRCA mutation: harmful pathogenic variant in BRCA1 or BRCA2, DNA repair genes. Raises breast cancer risk above 60% and ovarian cancer to 39%-58% (BRCA1); autosomal dominant; treated with PARP inhibitors.
BRCA1
BRCA1 (breast cancer type 1 susceptibility gene) is a tumor suppressor gene on chromosome 17q21 encoding a DNA-repair protein; pathogenic variants raise breast and ovarian cancer risk and guide PARP inhibitor therapy.
BRCA2
BRCA2 (breast cancer 2, early onset; MIM 600185) is a chromosome 13q12 tumor suppressor gene encoding a ~390 kDa mediator of RAD51-dependent homologous recombination; inherited mutations raise breast, ovarian, prostate, and pancreatic cancer risk and create PARP-inhibitor sensitivity.
BRCA2-interacting transcriptional repressor EMSY
EMSY (C11orf30), a human 11q13.5 gene encoding a 1,322-amino-acid BRCA2-binding transcriptional repressor; amplified in sporadic breast and ovarian cancer, producing BRCAness, with contested value as a PARP-inhibitor biomarker.
Brčko District
Brčko District (Brčko distrikat BiH) is a self-governing unit of Bosnia and Herzegovina, outside both Entities, created by the 5 March 1999 Final Award arbitration, inaugurated 8 March 2000, a condominium territory under international supervision.
BRCT domain
BRCT domain (BRCA1 C-terminal domain): a 90–100 amino acid protein-interaction module in DNA repair proteins across all life superkingdoms; tandem BRCTs bind pSer-X-X-Phe phosphopeptides, and BRCA1 BRCT mutations raise breast and ovarian cancer risk.
BRD2
BRD2 (bromodomain-containing protein 2, formerly RING3) is a human BET-family chromatin reader on chromosome 6p21.3 that binds acetylated histone H4, regulates transcription and TADs, and is linked to epilepsy, cancer, and inflammation.
BRD4
BRD4 (bromodomain-containing protein 4), a BET family epigenetic reader at 19p13.12, binds acetylated histones, releases paused Pol II, drives super-enhancer oncogene transcription, and is a major cancer drug target.
BRDC International Trophy
BRDC International Trophy, Silverstone motor racing award founded by the British Racing Drivers' Club in 1949; a non-championship Formula One race 1950-1980, later F2/F3000, revived 2026 for British F4, won by George Proudford-Nalder.
BRDM-2 (БРДМ-2)
The BRDM-2 (БРДМ-2), also designated BTR-40PB, is a Soviet amphibious 4x4 armored scout car adopted in 1962, produced until 1989, and exported to about 45 countries.
BrdU incorporation assay
The BrdU incorporation assay measures cell proliferation by detecting the thymidine analog BrdU incorporated into newly synthesized DNA during S phase, read out by immunofluorescence, flow cytometry, or ELISA.
BRE Coal Mine
The BRE coal mine is an opencast thermal coal mine at Rantau in Tapin Regency, South Kalimantan, Indonesia, operated by PT Bhumi Rantau Energi since 2010.
Bre-X
Bre-X, also known as Bre-X Minerals, was a mining company whose claimed gold discovery at Busang, Borneo, collapsed in 1997 in one of history's largest mining frauds.
Bre-Z
Bre-Z (Calesha Murray, born 1987, Philadelphia) is an American actress and rapper known as Freda Gatz on Empire and Tamia "Coop" Cooper on All American, and for her debut The Grl.
Brea
Brea (Βρέα) was an ancient Greek colony in Thrace founded by Athens, probably in 445 BC, and known from a founding decree found at the Erechtheion.
Breach (2020 film)
Breach (formerly Anti-Life) is a 2020 sci-fi action horror film directed by John Suits, starring Bruce Willis, Cody Kearsley, and Thomas Jane aboard a plague-fleeing interstellar ark; released December 18, 2020, it grossed $39,328 and holds 18% on Rotten Tomatoes.
Breach (Twenty One Pilots album)
Breach (2025) is the eighth studio album by Twenty One Pilots, released on Fueled by Ramen; its 13 tracks close the Dema lore begun on Blurryface, with singles The Contract, Drum Show, and City Walls.
Breach and termination of guaranteed neutrality
Breach and termination of guaranteed neutrality: how treaty-guaranteed neutralized states (Switzerland, Belgium, Luxembourg) were violated, notably by Germany in 1914 and 1940, and how Belgian neutrality was formally abrogated under Versailles Article 31 and Locarno.
Breach of contract
Breach of contract: failure without lawful excuse to perform contractual obligations, by non-performance, defective or delayed performance, or renunciation. Covers material versus minor breach, anticipatory breach, termination, expectation damages, mitigation, liquidated damages, and CISG remedies.
Breach of the peace
Breach of the peace is a UK common law concept covering actual or threatened violence disturbing public order. Defined by R v Howell [1982]; limited by Laporte's imminence test; in Scotland a common law crime.
Breaches of the Great Dam of Marib
The breaches of the Great Dam of Marib were the recorded failures of the ancient irrigation dam at Maʾrib in Yemen, with the final breach traditionally dated around AD 570.
Bread
Bread: leavened or unleavened baked staple made from flour-and-water dough; wheat is the main cereal, gluten traps fermentation gas; earliest known breadmaking at Shubayqa 1, Jordan, 14,400 years ago.
Bread (band)
Bread (band): American soft rock group formed 1968 in Los Angeles by David Gates, James Griffin, Robb Royer; Elektra act whose hits "Make It with You" (No. 1) and "If" defined early-1970s soft rock; disbanded 1973, reunited 1976-1977 and 1996-1997.
Bread (TV series)
Bread, BBC1 sitcom written by Carla Lane (1986–1991, 74 episodes), follows the Catholic Boswell family of Liverpool's Dingle surviving on benefits and fiddles under matriarch Nellie (Jean Boht); peaked at 21 million viewers.
Bread and circuses
Bread and circuses (panem et circenses), from Juvenal's Satire 10.77–81, names the Roman grain dole and public games; a phrase for pacifying a populace with food and entertainment.
Bread and Puppet Theater
Bread and Puppet Theater, founded 1963 by Peter Schumann in New York and based since 1974 on a Glover, Vermont farm, is a nonprofit political puppet company known for giant papier-mâché puppets, street pageants, free sourdough bread, and the Domestic Resurrection Circus.
Bread and Roses
Bread and Roses, also called the Lawrence Textile Strike of 1912, was a nine-week IWW-led walkout of about 20,000 immigrant textile workers in Lawrence, Massachusetts, triggered by a 32-cent pay cut; it won a 15 percent raise and overtime pay.
Bread and Roses (2023 film)
Bread and Roses (Bread & Roses) is Sahra Mani's 2023 Cannes-premiered documentary on three Afghan women resisting Taliban rule after the 2021 fall of Kabul, produced by Jennifer Lawrence and released on Apple TV+ in November 2024.
Bread and Wine
"Bread and Wine" (Brod und Wein) is a celebrated elegy by the German poet Friedrich Hölderlin, written in winter 1800/01, asking what poets are for in a destitute time.