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All articles starting with E

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Encenicline

Encenicline (EVP-6124, MT-4666) is a discontinued selective α7 nicotinic acetylcholine receptor partial agonist developed by Forum Pharmaceuticals for cognitive impairment in schizophrenia and Alzheimer's disease; Phase 2 trials were positive, but Phase 3 schizophrenia trials failed and FDA placed Alzheimer's trials on clinical hold over GI safety events.

Encephalartos

Encephalartos (bread trees), African-endemic cycad genus in Zamiaceae with 68 taxa, 85% threatened, dioecious cone-bearing plants pollinated by specialized insects; all species CITES Appendix I.

Encephalartos ferox

Encephalartos ferox, the holly-leafed cycad (Zamiaceae), native Mozambique to KwaZulu-Natal; glossy spiny holly-like leaflets, bright red cones, dioecious, IUCN Near Threatened, CITES Appendix I, about 100,000 mature individuals.

Encephalartos horridus

Encephalartos horridus, the Eastern Cape blue cycad, is an Endangered South African cycad with intense blue foliage, a ~431 km2 range, under 5,000 mature plants, heavy poaching, and CITES Appendix I listing.

Encephalartos woodii

Encephalartos woodii, Wood's cycad, a South African cycad from Ngoye Forest, KwaZulu-Natal, extinct in the wild since 1916. Only one male plant was ever found in 1895; all cultivated specimens are male clones, and no female exists.

Encephalitis

Encephalitis, also called acute encephalitis syndrome, is inflammation of the brain, a serious condition caused by brain infection or autoimmune attack, producing altered consciousness, seizures, and focal neurological deficits.

Encephalitis lethargica

Encephalitis lethargica, or von Economo's disease, is a brain inflammation first described in Vienna in 1917 that caused a worldwide epidemic from about 1916 to 1927, leaving somnolence, ophthalmoplegia, and postencephalitic parkinsonism; its cause remains unknown.

Encephalitis Viruses

Encephalitis viruses, also called neurotropic or arboviral encephalitis viruses, include Japanese encephalitis, West Nile, tick-borne encephalitis, equine encephalitis, and herpes simplex viruses that infect the brain, distinguished by vector, reservoir, and severity.

Encephalitozoon

Encephalitozoon is a genus of microsporidian fungi, intracellular parasites of mammals and birds; species E. cuniculi, E. hellem, and E. intestinalis infect rabbits, birds, and humans via polar-tube-bearing spores.

Encephalitozoon cuniculi

Encephalitozoon cuniculi, an obligate intracellular microsporidian parasite of rabbits (genotypes ECI–ECIII) that also infects cats, dogs, and humans, causing neurological, ocular, renal, and disseminated disease; smallest known eukaryotic genome at 2.9 Mb.

Encephalization quotient

Encephalization quotient (EQ), Jerison's 1973 brain-size measure from Dubois' 1897 equation: actual brain mass divided by expected brain mass for body size. Humans score about 6; clade-specific equations and cognitive-prediction limits are key caveats.

Encephalocraniocutaneous lipomatosis

Encephalocraniocutaneous lipomatosis (ECCL, Haberland syndrome) is a rare sporadic mosaic RASopathy caused by postzygotic FGFR1 or KRAS variants, featuring nevus psiloliparus, ocular choristomas, CNS lipomas, seizures, and low-grade glioma risk.

Encephaloduroarteriosynangiosis

Encephaloduroarteriosynangiosis (EDAS) is an indirect brain revascularization operation, introduced in 1981, in which a scalp artery is laid on the brain surface to treat moyamoya disease.

Encephalomyocarditis virus

Encephalomyocarditis virus (EMCV), also called Mengo virus, is a rodent-borne Cardiovirus picornavirus with a ~7.8 kb positive-sense RNA genome. It causes sudden-death myocarditis in pigs and zoo animals; human infections are mild and rarely fatal.

Encephalomyocarditis virus infection

Encephalomyocarditis virus infection (EMCV, Cardiovirus, Picornaviridae) is a rodent-borne picornavirus disease of swine and zoo mammals causing sudden death from myocarditis; two serotypes, EMCV-1 and EMCV-2; zoonotic but rarely causes human disease.

Encephalopathy

Encephalopathy, also called acute or metabolic encephalopathy, is diffuse brain dysfunction from systemic causes such as sepsis, organ failure, toxins, or metabolic derangement; delirium is its clinical phenotype, and coma its severe end.

Encephalopathy due to ammonia

Encephalopathy due to ammonia (ICD-11 8D43.00, アンモニアによる脳症), or hyperammonemic encephalopathy: toxic brain dysfunction from elevated blood ammonia, causing astrocyte glutamine-driven cerebral edema; seen in hepatic encephalopathy, urea cycle disorders, drugs, and infections.

Encequidar

Encequidar (HM30181) is a minimally absorbed, gut-specific P-glycoprotein inhibitor by Hanmi/Athenex that enables oral paclitaxel (Oraxol); phase III in metastatic breast cancer showed higher response and less neuropathy than IV paclitaxel; not approved.

EnChannel Medical (心航路医学)

EnChannel Medical (心航路医学) is a Chinese medical device startup founded in 2020 in Guangzhou that develops cardiac mapping and pulsed-field ablation systems for treating atrial fibrillation.

Enchanté (ใครคือ… อองชองเต)

Enchanté (ใครคือ… อองชองเต) is a 2022 GMMTV Thai BL series, 10 episodes on GMM25, adapted from NinePinta's novel, starring Force and Book as Akk and Theo, who seeks the mysterious library correspondent Enchanté among four suitors.

Enchanted (film)

Enchanted is a 2007 American musical fantasy comedy film directed by Kevin Lima and starring Amy Adams, Patrick Dempsey, and James Marsden, blending animation with live action in Manhattan.

Enchanted April (1991 film)

Enchanted April is a 1991 British comedy-drama directed by Mike Newell, adapted from Elizabeth von Arnim's 1922 novel, in which four Englishwomen rent a castle on the Italian Riviera for April.

Enchanted Parks

Enchanted Parks is an American company based in Windermere, Florida, founded by James Harhi, that owns and operates amusement parks, water parks, resorts, and lodging destinations.

Enchanted Princess

Enchanted Princess is a Royal-class cruise ship of Princess Cruises, built by Fincantieri in Italy and delivered in 2020; she began service in November 2021 after pandemic delays.

Enchanted Rock

Enchanted Rock is a pink granite exfoliation dome in the Texas Hill Country, the centerpiece of Enchanted Rock State Natural Area near Fredericksburg; a billion-year-old batholith, National Natural Landmark, and one of Texas's most visited parks.

ENCHANTED trial

ENCHANTED (Enhanced Control of Hypertension and Thrombolysis Stroke Study) is an international 2x2 randomized stroke trial of low-dose vs standard-dose alteplase and intensive vs guideline blood pressure lowering; its successor ENCHANTED2/MT tested SBP targets after thrombectomy.

Enchanted Valley Carnival

The Enchanted Valley Carnival (EVC) was a multi-genre music and camping festival held annually from 2013 at Aamby Valley City in Maharashtra, India, ending after its fifth edition in 2017.

Enchanting (rapper)

Enchanting, born Channing Nicole Larry (1997-2024), was a Fort Worth, Texas rapper and singer signed to Gucci Mane's 1017 Records in 2020, known for "No Luv" and the Trap-n-Blues blend of rap and R&B; she died June 11, 2024, of an accidental oxycodone and benzodiazepine overdose.

Enchantress (DC Comics)

Enchantress (June Moone) is DC Comics' witch-sorceress, created by Bob Haney and Howard Purcell, debuting in Strange Adventures #187 (April 1966); June Moone transforms by speaking her name, serving the Suicide Squad, Shadowpact, and Justice League Dark, and was played by Cara Delevingne in the 2016 film.

Enchantress (Marvel Comics)

Enchantress (Marvel Comics): the alias of Amora, an Asgardian sorceress who debuted in Journey Into Mystery #103 (1964) as Loki's ally against Thor, and of Sylvie Lushton, a Loki-empowered human who imitated her from 2009; distinct from DC's June Moone Enchantress.