All articles starting with F
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Follicle stimulating hormone receptor
FSHR (follicle-stimulating hormone receptor, follitropin receptor) is a class A GPCR on chromosome 2, expressed in granulosa and Sertoli cells, mediating FSH signaling; mutations cause amenorrhea, POF, infertility, or OHSS.
Follicle-stimulating hormone
Follicle-stimulating hormone (FSH, follitropin) is an anterior pituitary glycoprotein gonadotropin with common alpha and unique beta subunits; it drives ovarian follicle growth via granulosa-cell FSHR and Sertoli-cell support of spermatogenesis, and is used in fertility treatment.
Follicular B cell
Follicular B cell (Fo B cell, B-2 cell): a resting recirculating mature B cell (IgM+, IgD+, CD23+, CD21+) of spleen and lymph node follicles; bulk of the peripheral B cell pool, driven by BCR and BAFF signaling, source of germinal center and plasma cell responses.
Follicular carcinoma of thyroid gland
Follicular thyroid carcinoma (FTC), a malignant follicular-cell thyroid tumor, second most common thyroid cancer after papillary; diagnosis requires capsular or vascular invasion, treated with lobectomy or total thyroidectomy plus radioactive iodine.
Follicular conjunctivitis
Follicular conjunctivitis, ICD-11 9A60.1, is conjunctival inflammation with lymphoid follicles, usually viral (adenovirus) or chlamydial, sometimes toxic from eye drops; follicles distinguish it from papillary bacterial or allergic conjunctivitis.
Follicular cyst of ovary
Follicular cyst of ovary (cyst of graafian follicle, ICD-11 GA18.0): a non-neoplastic fluid-filled ovarian sac lined by granulosa cells, formed when a follicle fails to ovulate; usually asymptomatic, resolves in 8-12 weeks, and oral contraceptives do not hasten resolution.
Follicular dendritic cell
Follicular dendritic cells (FDCs) are stromal, non-hematopoietic cells in B cell follicles that trap native antigen as immune complexes, drive germinal center reactions and antibody affinity maturation, and serve as an HIV reservoir.
Follicular dendritic cell sarcoma
Follicular dendritic cell sarcoma (FDCS), formerly follicular dendritic cell tumor, is a rare mesenchymal-derived sarcoma of B-follicle stromal cells, mostly extranodal (79.4%), treated by complete surgical excision, with local recurrence in 28% and metastasis in 27%.
Follicular epithelial cell
Follicular epithelial cell (Cell Ontology CL:0000500): an epithelial somatic cell associated with a maturing oocyte; in mammals the granulosa cells of the membrana granulosa, in insects the egg-chamber follicle cells.
Follicular lymphoma
Follicular lymphoma (FL) is an indolent B-cell non-Hodgkin lymphoma with nodular growth, t(14;18) IGH::BCL2 in 85% of cases, median survival near 20 years, and risk of DLBCL transformation.
Follicular lymphoma grade 1
Follicular lymphoma grade 1 (ICD-O-3 9695/3, ICD-11 2A80.0) is the lowest-grade, indolent follicle center B-cell non-Hodgkin lymphoma, defined by 0–5 centroblasts per high-power field, t(14;18) in up to 90% of grades 1–2, and treatment as indolent disease.
Follicular lymphoma grade 2
Follicular lymphoma grade 2 (ICD-11 2A80.1) is an indolent germinal-center B-cell lymphoma with 6-15 centroblasts per high-power field, grouped with grade 1 as grade 1-2 FL and optional in WHO-HAEM5.
Follicular lymphoma grade 3
Follicular lymphoma grade 3 (FL3, grades 3A and 3B) is an aggressive subtype of follicular B-cell non-Hodgkin lymphoma with over 15 centroblasts per high-power field; grade 3B is treated like diffuse large B-cell lymphoma.
Follicular lymphoma in situ
Follicular lymphoma in situ, now in situ follicular B-cell neoplasm (ISFN), is an incidental t(14;18)-positive BCL2/CD10-strong colonization of germinal centers in reactive nodes, with low progression risk (about 5%).
Follicular phase
Follicular phase: first phase of the menstrual cycle, from the first day of menstruation to ovulation, when FSH matures ovarian follicles and one dominant follicle releases an egg; typically 10-17 days and the main source of cycle length variability.
Follicular unit extraction
Follicular unit extraction (FUE) is a hair transplantation technique that harvests intact follicular units through small punch incisions, avoiding the linear donor scar left by strip harvesting.
Folliculin
Folliculin (FLCN), tumor suppressor protein of 579 amino acids encoded by FLCN on 17p11.2; GAP for RagC/D GTPases with FNIP1/FNIP2 and AMPK; germline mutations cause Birt-Hogg-Dubé syndrome.
Folliculitis
Folliculitis is inflammation of hair follicles from infection (Staphylococcus aureus, Pseudomonas), Malassezia yeast, irritation, or drugs, causing itchy or painful pustules; treatment depends on cause, with weak antibiotic trial evidence.
Folliculotropic mycosis fungoides
Folliculotropic mycosis fungoides (follicular, pilotropic MF) is a WHO-EORTC-recognized variant of mycosis fungoides in which T cells infiltrate hair follicles, sparing the epidermis, favoring head and neck, with follicular mucinosis, eyebrow plaques, alopecia, and stage-dependent survival.
Follies
Follies is a 1971 Stephen Sondheim musical with a book by James Goldman, about a reunion of Weismann Follies showgirls before their theatre's demolition. Known for its pastiche score, Loveland sequence, seven 1972 Tonys, and the 1987, 2001, 2011, and 2017 revivals.
Follies (film)
Follies (Folichonneries) is a 2025 Canadian comedy-drama, Eric K. Boulianne's directorial debut, starring Boulianne and Catherine Chabot as a couple of 16 years who open their relationship; premiered at Locarno 2025, released in Quebec January 30, 2026.
Follistatin-like, N-terminal
Follistatin-like, N-terminal (FOLN, Pfam PF09289, InterPro IPR003645) is an EGF-like cysteine-rich domain found in follistatin and osteonectin; in follistatin it carries essential activin-binding determinants.
Follitropin alfa
Follitropin alfa, marketed as GONAL-f, is a recombinant form of human follicle-stimulating hormone used to stimulate ovarian follicle growth in fertility treatment and sperm production in men.
Follitropin beta
Follitropin beta (Puregon, Follistim AQ) is a recombinant human FSH made in CHO cells from a single vector, EU-licensed 1996, used for ovulation induction, IVF stimulation, and spermatogenesis induction.
Follo Line
The Follo Line (Follobanen) is a 22 km double-track railway in Norway running from Oslo S to Ski, opened in December 2022 and halving journey times to 11 minutes.
Follow Me (Uncle Kracker song)
"Follow Me" is Uncle Kracker's 2000 debut solo single from Double Wide, written with Michael Bradford and produced by Kid Rock; it hit No. 5 on the Billboard Hot 100, No. 3 in the UK, and No. 1 in five countries.
Follow Me My Friend / To Glory at the End
Follow Me My Friend / To Glory at the End is episode 8 of Agatha All Along season 1, the first half of the finale, aired October 30, 2024; written by Peter Cameron, directed by Gandja Monteiro, it features Agatha's death and the Witches' Road reveal.
Follow the Fleet
Follow the Fleet is a 1936 RKO musical comedy directed by Mark Sandrich, the fourth or fifth Astaire-Rogers film, with Irving Berlin songs including Let's Face the Music and Dance, set on Navy shore leave in San Francisco.
Follow the Leader (Eric B. & Rakim album)
Follow the Leader is Eric B. & Rakim's second studio album, released July 25, 1988 on Uni Records (UNI-3), recorded at Power Play Studios; it peaked at No. 22 on Billboard's Top Pop Albums chart and includes "Microphone Fiend" and "Lyrics of Fury."
Follow the Leader (Я) (Korn album)
Follow the Leader (Я), Korn's third album (Immortal/Epic, August 18, 1998), debuted at number one on the Billboard 200, the first nu-metal album to do so, and launched "Freak on a Leash". Producers Steve Thompson, Toby Wright, Korn; recorded 18 weeks at NRG Studio B on a $750,000 budget.