All articles starting with H
20,046 articles
Hereditary sensory and autonomic neuropathy type 6
HSAN6 (HSAN VI, OMIM 614653) is a rare autosomal recessive sensory and autonomic neuropathy caused by DST (dystonin) mutations, with pain insensitivity, painless fractures, ulcers, and dysautonomia; severity ranges from lethal infancy to adult-onset forms. Distinct from the PRDM12 disorder some papers also call HSAN6.
Hereditary sensory and autonomic neuropathy type 8
HSAN8 (HSAN type VIII, PRDM12-related congenital insensitivity to pain, OMIM 616488) is an autosomal recessive, neonatal-onset disorder causing congenital pain and temperature insensitivity, corneal scarring, reduced sweating, and self-mutilating injuries with preserved touch and intellect.
Hereditary sensory neuropathy-deafness-dementia syndrome
Hereditary sensory neuropathy-deafness-dementia syndrome (HSAN1E, OMIM 614116) is a rare autosomal dominant DNMT1 mutation disorder causing sensorineural hearing loss, sensory neuropathy, and dementia from adolescence or adulthood, fatal in the fifth to sixth decade.
Hereditary sick sinus syndrome
Hereditary sick sinus syndrome: inherited sinus node dysfunction from SCN5A, HCN4, LMNA variants; autosomal dominant or recessive; 2.9-fold familial pacemaker risk; testing yield under 25%.
Hereditary sideroblastic anaemias
Hereditary sideroblastic anaemias (XLSA, SLC25A38 CSA) are inherited anemias with ring sideroblasts from mitochondrial iron loading, ALAS2 mutations most common, pyridoxine-responsive in two-thirds, with systemic iron overload.
Hereditary soldier-household system (shijia)
The hereditary soldier-household system (士家制) was a Cao Wei policy begun under Cao Cao around 204 that made soldiers' families a hereditary military class with lifelong service.
Hereditary spastic paraplegia
Hereditary spastic paraplegia (HSP), or Strümpell-Lorrain syndrome, is a group of inherited disorders causing progressive leg spasticity and weakness from corticospinal tract degeneration; over 80 genes, SPG4 most common, pure form in about 90%.
Hereditary spherocytosis
Hereditary spherocytosis (Minkowski-Chauffard disease), the most common red cell membrane disorder, an inherited hemolytic anemia from ankyrin, band 3, or spectrin defects causing splenic destruction of spherocytes; splenectomy treats severe cases.
Hereditary steroid-resistant nephrotic syndrome
Hereditary steroid-resistant nephrotic syndrome, also called genetic steroid-resistant nephrotic syndrome, is a rare inherited kidney disease that fails to respond to corticosteroids and is caused by variants in genes maintaining the glomerular filtration barrier.
Hereditary thrombocytopenia
Hereditary (inherited) thrombocytopenia: germline genetic disorders causing platelet counts below 150 × 10⁹/L, over 40 implicated genes, forms such as MYH9-related disease, Bernard-Soulier syndrome, Wiskott-Aldrich syndrome, and ANKRD26-related thrombocytopenia, often misdiagnosed as immune thrombocytopenia.
Hereditary thrombophilia
Hereditary thrombophilia: inherited clotting defects (antithrombin, protein C, protein S deficiency; factor V Leiden; prothrombin G20210A) raising venous thromboembolism risk; testing recommended only in selective clinical scenarios.
Hereditary title
A hereditary title is a noble or official rank passed down within a family, usually to the eldest son; the best-known example is the British hereditary peerage.
Hereditary xanthinuria
Hereditary xanthinuria (classic xanthinuria, xanthine stone disease, ORPHA:3467) is a rare autosomal recessive purine metabolism disorder caused by XDH or MOCOS mutations, causing hypouricemia, high urinary xanthine, and xanthine kidney stones in about half of patients.
Heredity
Heredity is the passing of genes from parents to offspring, studied by genetics. Key facts: 46 human chromosomes, Mendel's 28,000 pea plants, six single-gene inheritance patterns, heritability, and epigenetic inheritance.
Hereford
Hereford, cathedral city and county town of Herefordshire, England, on the River Wye near the Welsh border; population about 58,000–62,000. Known for the Mappa Mundi, Hereford cattle, cider, and severe A49 congestion addressed by a planned bypass.
Hereford Cathedral
Hereford Cathedral, formally the Cathedral Church of St Mary and St Ethelbert, is a Grade I listed Church of England cathedral in Hereford, home to Mappa Mundi and the world's largest surviving chained library.
Hereford F.C.
Hereford F.C., nicknamed The Bulls, is the phoenix club formed in 2014 after Hereford United's winding-up; it plays at Edgar Street (capacity 7,100), won three straight promotions to the National League North, and is 50.1% owned by supporters.
Hereford Mappa Mundi
The Hereford Mappa Mundi is a medieval world map drawn around 1300 on calfskin vellum and displayed at Hereford Cathedral, the largest surviving medieval mappa mundi.
Hereford United F.C.
Hereford United F.C., English football club formed 1924 at Edgar Street, Hereford; famous 1972 FA Cup win over Newcastle; Football League 1972-1997 and 2006-2012; wound up 19 December 2014, succeeded by Hereford FC.
Herefordshire
Herefordshire, formally the County of Herefordshire, is a rural county in western England on the border with Wales, governed as a unitary authority from Hereford.
Herefordshire Konservat-Lagerstätte Formation
Herefordshire Konservat-Lagerstätte: Silurian (Wenlock, ~430 Ma) fossil deposit in the Welsh Borderland, England, preserving soft-bodied marine invertebrates as 3D calcite infills in nodules in volcanic ash; studied by serial grinding and virtual reconstruction.
Hereke carpet
A Hereke carpet is a hand-knotted Turkish carpet first woven from 1891 at an imperial factory near Istanbul, known for fine Bursa silk and floral palace designs.
Herencia de Patrones
Herencia de Patrones, a corridos tumbados group formed in 2017 (Yuba City, California per Apple Music; Mexico per AllMusic), blends requinto, bajo sexto, and tuba with hip-hop flow; Rancho Humilde act behind Pa Las Vibras and El Mundo Es Tuyo.
Herero and Nama genocide
The Herero and Nama genocide (1904–1908) was the German colonial annihilation campaign in German South West Africa, today Namibia, under General Lothar von Trotha, killing an estimated 35–80% of Herero and up to half the Nama; Germany recognized it as genocide in 2021.
Herero and Nama Wars
The Herero and Nama Wars were the wars between the Herero and Nama peoples and Imperial Germany in present-day Namibia from 1904 to 1907, widely classified as genocide.
Herero people
The Herero (Ovaherero) are Bantu-speaking pastoralists of Namibia, Botswana, and Angola speaking Otjiherero, divided into Ovaherero, Ovambanderu, and Ovahimba; they suffered the 1904-1908 German genocide and lead ongoing reparations efforts.
Heresy
Heresy is the obstinate denial or doubt, by a baptized member, of a truth a religious community defines as requiring belief, punished in Catholic law by excommunication.
Heresy in Christianity
Heresy in Christianity, also called Christian heresies, is the obstinate denial by a baptized person of a truth of faith, condemned from Nicaea onward and once punished by burning.
Heretic (2024 film)
Heretic (2024) is an A24 psychological horror-thriller written and directed by Scott Beck and Bryan Woods, starring Hugh Grant as Mr. Reed, who traps two Latter-day Saint missionaries (Sophie Thatcher, Chloe East). Released November 8, 2024; grossed about $60 million on a $10 million budget; 89% on Rotten Tomatoes.
Heretic (video game)
Heretic (1994) is a dark fantasy first-person shooter by Raven Software, published by id Software, on a modified DOOM engine, starring the Sidhe elf Corvus; known as the first Doom clone, it pioneered inventories and vertical aiming, and got the Heretic + Hexen remaster in 2025.