All articles starting with H
20,046 articles
HLA-A
HLA-A: classical MHC class I gene on chromosome 6 encoding a peptide-presenting molecule for CD8+ T cells; highly polymorphic, first class I structure solved (HLA-A2), central to transplant typing.
HLA-B
HLA-B (major histocompatibility complex, class I, B) is a highly polymorphic human MHC class I gene presenting peptides to CD8+ T cells; HLA-B27 links to ankylosing spondylitis, HLA-B51 to Behçet disease, and HLA-B*57:01 to abacavir hypersensitivity.
HLA-B27
HLA-B27, an HLA-B gene allele encoding an MHC class I antigen, is the strongest known common-variant disease association, linked to ankylosing spondylitis, reactive arthritis, and anterior uveitis since its 1973 discovery.
HLA-C
HLA-C (major histocompatibility complex, class I, C) is the third classical human MHC class I gene at 6p21.33, encoding a beta-2 microglobulin-paired peptide-presenting chain, distinguished by low cell-surface expression and KIR ligand groups C1 and C2.
HLA-DPB1
HLA-DPB1 (major histocompatibility complex, class II, DP beta 1), also called DPB1 or HLA-DP1B, is a polymorphic chromosome 6p21.32 gene encoding the beta chain of the HLA-DP antigen-presenting molecule, linked to beryllium disease, GPA, and transplant matching.
HLA-DQA1
HLA-DQA1 (DQ alpha 1) is a human MHC class II gene at 6p21.32 encoding the alpha chain of the HLA-DQ antigen-presenting heterodimer with HLA-DQB1; its DQ2/DQ8 variants are the major celiac disease risk factors.
HLA-DQB1
HLA-DQB1 (IDDM1, CELIAC1) is a chromosome 6p21.32 MHC class II gene encoding the DQ beta chain; its DQ2, DQ8, and DQB1*06:02 alleles shape risk of celiac disease, type 1 diabetes, and narcolepsy.
HLA-DR
HLA-DR (human leukocyte antigen D-related) is an MHC class II molecule presenting peptides to CD4+ T cells, with a conserved DRA alpha chain and beta chains from DRB1, DRB3, DRB4, or DRB5 genes defining DR51, DR52, and DR53 groups.
HLA-DRA
HLA-DRA (major histocompatibility complex, class II, DR alpha) is the essentially monomorphic human gene at 6p21.32 encoding the shared alpha chain of HLA-DR class II antigen-presenting molecules paired with DRB1, DRB3, DRB4, and DRB5 beta chains.
HLA-DRB1
HLA-DRB1 (major histocompatibility complex, class II, DR beta 1) is a highly polymorphic human MHC class II gene on chromosome 6p21.3 encoding the DR beta chain; its alleles drive rheumatoid arthritis and multiple sclerosis risk and guide transplant matching.
HLA-DRB3
HLA-DRB3 (DR beta 3, DR52) is a human MHC class II beta-chain gene at 6p21.3, carried on DR3/DR5/DR6 haplotypes, less polymorphic than DRB1, expressed at lower levels, and relevant to transplant matching and membranous nephropathy.
HLA-DRB5
HLA-DRB5 (DRB5) is a protein-coding HLA class II beta chain gene at 6p21.32, named in 1989, carried on DR2 (DRB1*15/16) haplotypes and defining the DR51 specificity; its beta chain dimerizes with DRA and is typed for transplantation.
HLA-E
HLA-E is a non-classical MHC class I protein on chromosome 6 that presents leader peptides from other HLA molecules to NK cell receptors, influencing immunity, infection, and cancer immunotherapy.
HLA-G
HLA-G, human leukocyte antigen G, is a nonclassical MHC class I molecule on chromosome 6p21 with seven splice isoforms that suppress immunity via LILRB1, LILRB2, and KIR2DL4, enabling fetal tolerance, graft acceptance, and tumor immune escape.
Hlai people
The Hlai people, also known as the Li people, are the indigenous Tai-Kadai-speaking inhabitants of Hainan Island. They are known for their Li brocade and pottery.
Hlaingthaya
Hlaingthaya (လှိုင်သာယာ), also spelled Hlaing Tharyar, is a western Yangon township, Myanmar, created in 1987-1989 for resettled squatters and fire victims, home to the 1995 Hlaingthaya Industrial Zone, over 850 factories, and Yangon's largest informal settlements.
Hlawga National Park
Hlawga National Park, an open zoo and nature park 22 miles north of Yangon in Mingaladon Township, Myanmar; 1,540 acres with safari park, mini zoo, and buffer zone; opened 1989; popular for birdwatching, SUP, and camping.
Hlineu Corona
Hlineu Corona is a 150-km-diameter corona on Venus at 38.7 S, 241 E, IAU-named in 1997 for a Chin/Kieng ancestor goddess, with an asymmetric, multi-stage fracture annulus and extensive corona-related lava flows.
HLM Strategic Investment Fund
HLM Strategic Investment Fund is a $230 million healthcare-focused venture capital fund closed in October 2021 by HLM, a Massachusetts healthcare venture firm founded in 1983.
Hlm Venture Partners
HLM Venture Partners, now called HLM Investment Partners, is a venture capital firm based in Waltham and Boston, Massachusetts, founded in 1983 and investing exclusively in healthcare, with about $400 million in assets.
HLN (TV network)
HLN (TV network), formerly CNN2 and Headline News, is a Warner Bros. Discovery cable channel launched January 1, 1982 as CNN's sister headline service; since December 2022 it airs mostly true crime plus a CNN This Morning simulcast, distinct from Belgium's HLN newspaper.
HLS Therapeutics Inc.
HLS Therapeutics Inc., formerly Heritage Life Sciences Inc., is a Canadian specialty pharmaceutical company founded in 2014 and headquartered in Etobicoke, Ontario, best known for acquiring Clozaril for treatment-resistant schizophrenia.
HLSL
HLSL, or High-Level Shading Language, is a C-based shading language developed by Microsoft for writing GPU shaders in DirectX, introduced with DirectX 9.0 in 2003.
HLTV
HLTV, also known as HLTV.org, is a Danish website covering competitive Counter-Strike with news, live scores, and statistics. Founded in 2002, it is owned by Better Collective.
Hlukhiv Articles
The Hlukhiv Articles (Hlukhivski Stati) were a 27-point accord signed at Hlukhiv on 16 March 1669 between Muscovy and Demian Mnohohrishny, hetman of Left-Bank Ukraine.
Hluttaw
The Hluttaw (လွှတ်တော်) was the council of ministers serving as the center of government in the Burmese royal court, combining fiscal, executive, and judicial functions until 1885.
HLX35
HLX35 (BNA035) is a recombinant humanized EGFR x 4-1BB bispecific antibody from Shanghai Henlius, licensed to Binacea for ex-China territories, tested in phase 1 solid tumor trials and later suspended by company decision.
Hlyboka Raion
Hlyboka Raion (Глибоцький район) was a raion of Chernivtsi Oblast, Ukraine, with its administrative center in the urban-type settlement of Hlyboka until it was abolished in 2020.
HM Prison Belmarsh
HM Prison Belmarsh: high-security men's prison in Thamesmead, southeast London, opened 18 July 1991. Only reception prison in the high-security estate, with a high security unit for category A prisoners.
HM Prison Bronzefield
HMP Bronzefield, Ashford, Middlesex: first purpose-built private women's prison in the UK, opened 17 June 2004, run by Sodexo; largest women's prison in Europe after Holloway closed.