edgepedia

All articles starting with H

20,046 articles

HS Produkt VHS

The HS Produkt VHS is a Croatian 5.56×45 mm NATO bullpup assault rifle made by HS Produkt and issued as the standard rifle of the Croatian Armed Forces.

HS Psc

HS Psc is a young (about 130 Myr) K7 V star 37.7 parsecs away in Pisces, an AB Doradus moving group member hosting HS Psc b, a 1.46-Jupiter-mass hot Jupiter in a 3.986-day orbit, discovered by radial velocity in 2024.

HS-10353

HS-10353 is Hansoh Pharmaceutical's investigational oral GABA-A receptor positive allosteric modulator, a zuranolone-like small molecule in Phase 2 trials for major depressive and postpartum depression, with Phase 1 efficacy and safety data published.

HS-10380

HS-10380 (Obuprazine, TRTL-107) is Hansoh Pharma's oral D2/D3 and 5-HT1A partial agonist, 5-HT2A antagonist antipsychotic for schizophrenia; Phase 2b showed PANSS gains versus placebo and aripiprazole, now in Phase 3.

HS-10535

HS-10535, also known as MK-4082, is an investigational oral small-molecule GLP-1 receptor agonist for obesity developed by China's Hansoh Pharma and globally licensed to Merck & Co. in December 2024.

HS-20094

HS-20094 (olatorepatide, 奥莱泊肽) is Hansoh Pharma's once-weekly dual biased GLP-1/GIP receptor agonist for diabetes and obesity, licensed to Regeneron outside Greater China; Phase 3 showed up to 19.3% weight loss at 48 weeks.

HS-20118 (AVR-001)

HS-20118 (AVR-001) is Hansoh Pharma's oral cyclic peptide interleukin-23 receptor antagonist for moderate-to-severe plaque psoriasis, licensed to Avere Therapeutics in 2026; Phase 1 data showed a 6-7 day half-life supporting once-weekly dosing and PASI 75 rates up to 75%.

HS-376

HS-376 is a spin-stabilized commercial communications satellite bus built by Hughes, carrying data, voice, and television; 58 satellites using it were launched between 1980 and 2003.

HS-601

The HS-601 is a three-axis, body-stabilized geostationary communications satellite bus developed by Hughes Space and Communications in California, introduced in 1987, with 84 spacecraft ordered by 17 customers.

HS2 rolling stock

HS2 rolling stock is the fleet of 54 fully electric high-speed trains ordered in December 2021 from a Hitachi-Alstom joint venture under a £1.97 billion contract for Britain's HS2 railway.

HS2000

The HS2000 is a Croatian 9mm semi-automatic pistol developed for the Croatian army in the late 1990s and sold in the US as the Springfield XD.

HSAB theory

HSAB theory, or hard and soft acids and bases, is a qualitative chemistry principle stating that hard acids bind hard bases and soft acids bind soft bases.

HSBC

HSBC, also known as HSBC Holdings plc, is a British multinational bank founded in Hong Kong in 1865 and headquartered in London, serving about 41 million customers across 58 countries.

HSBC Bank Canada

HSBC Bank Canada, formerly Hongkong Bank of Canada, was a Vancouver-headquartered foreign subsidiary bank with about $120 billion in assets, Canada's seventh largest, acquired by RBC in 2024.

HSC Hoverspeed Great Britain

HSC Hoverspeed Great Britain was a 73.6-meter wave-piercing catamaran ferry built by Incat in 1990 for the British cross-Channel operator Hoverspeed, the first of her type to carry vehicles commercially.

HSC-2

HSC-2 (HSC2, CVCL_1287, JCRB0622) is a well-differentiated human oral squamous cell carcinoma cell line established in 1989 in Japan from a 69-year-old man, carrying PIK3CA His1047Arg and TP53 splice mutations, non-invasive, and used in drug-screening panels.

HSC-3

HSC-3 (HSC3, JCRB0623, CVCL_1288) is a human oral squamous carcinoma cell line established in 1989 from a 64-year-old Japanese man's tongue cancer, derived from a cervical lymph node metastasis, with high metastatic potential and wide use in OSCC research.

HSC-4

HSC-4 (HSC4, CVCL_1289, JCRB0624) is a human tongue squamous cell carcinoma cell line established in 1989 from a 64-year-old Japanese man's cervical lymph node metastasis, used in over 150 OSCC studies.

HSC-84

HSC-84, known as the "Red Wolves," was a US Navy Reserve helicopter squadron at Norfolk, Virginia, dedicated to Naval Special Warfare support and Strike Rescue until 2016.

HSC-85

HSC-85 (Helicopter Sea Combat Squadron 85), nicknamed the Firehawks, was a US Navy Reserve helicopter squadron at NAS North Island supporting special operations forces, deactivated in 2023.

HSD10 disease

HSD10 disease, also called HSD10 mitochondrial disease, is a rare X-linked neurometabolic disorder caused by HSD17B10 gene variants, fatal in most affected boys by early childhood.

HSD11B1

HSD11B1 (11β-HSD1, SDR26C1) is a human gene at 1q32.2 encoding a microsomal, NADP(H)-dependent enzyme that interconverts cortisol and cortisone, acting mainly as a cortisone reductase; mutations cause cortisone reductase deficiency and it is a drug target in metabolic and immune disease.

HSD11B2

HSD11B2 (hydroxysteroid 11-beta dehydrogenase 2, 11β-HSD2) is a human gene on 16q22.1 encoding an NAD-dependent enzyme that inactivates cortisol to cortisone, protecting the mineralocorticoid receptor and the fetus; defects cause apparent mineralocorticoid excess.

HSD17B1

HSD17B1 (hydroxysteroid 17-beta dehydrogenase 1, also EDH17B2, SDR28C1) is a human gene at 17q21.2 encoding 17β-HSD1, a 34.5-kDa homodimeric SDR enzyme that reduces estrone to estradiol using NADPH, inactivates androgens, and is a drug target in breast cancer and endometriosis.

HSDPA

HSDPA (High Speed Downlink Packet Access) is a packet-data enhancement of WCDMA, introduced in 3GPP Release 5, that raises downlink data rates and capacity in a cell.

Hsekiu

Hsekiu, recorded in hieroglyphs as Seka, is a predynastic king of Lower Egypt named only in the Palermo Stone royal annals, where he stands second among the preserved Delta kings and is generally regarded as legendary.

Hsenwi

Hsenwi, also known as Theinni, was the largest of the cis-Salween Shan States of northeastern Burma, split by the British into North and South Hsenwi in 1888.

HSF1

HSF1 (heat shock factor 1), master transcriptional regulator of the heat shock response, induces HSP chaperone genes via stress-triggered trimerization and HSE binding; elevated in cancer, degraded in Huntington disease.

HSG

HSG (Human Salivary Gland, CVCL_2517) is a human cancer cell line established in 1981 from an irradiated submandibular salivary gland but shown by STR profiling to be a HeLa derivative; ICLAC-00313, distinct from the HGS1-4 ovarian series.

Hsia Yu

Hsia Yu (夏宇), also known as Li Kedi (李格弟), is a Taiwan-based poet and pop lyricist whose 1984 debut collection, Memorandum, influenced a generation of writers.