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All articles starting with I

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Ifeye

Ifeye (이프아이) is a six-member South Korean girl group under Hi-Hat Entertainment, produced by RyuD, that debuted April 8, 2025 with the EP ERLU BLUE and title track NERDY, followed by sweet tang (2025) and As if (2026).

IFFHS World's Best Goalkeeper

IFFHS World's Best Goalkeeper: annual men's goalkeeper award by the International Federation of Football History & Statistics, voted for the calendar year since 1987; first winner Jean-Marie Pfaff; Casillas, Buffon, and Neuer each won five times.

IFI16

IFI16 (IFNGIP1, PYHIN2), human PYHIN-family nuclear DNA sensor with PYD and two HIN domains; senses viral dsDNA, drives STING interferon signaling, ASC inflammasomes, and viral gene silencing; absent in mice.

IFIH1

IFIH1 (interferon induced with helicase C domain 1, HGNC:18873) encodes MDA5, a cytoplasmic RIG-I-like receptor sensing long viral dsRNA via MAVS to induce type I interferon; gain-of-function causes Aicardi-Goutieres and Singleton-Merten syndromes, loss-of-function causes severe viral infections.

Ifinatamab deruxtecan

Ifinatamab deruxtecan (I-DXd, DS-7300) is a B7-H3-directed antibody-drug conjugate with a DXd topoisomerase I inhibitor payload, DAR 4, developed by Daiichi Sankyo and Merck for SCLC, prostate, and esophageal cancers; FDA priority review 2026.

IFIT1

IFIT1, also known as P56 or ISG56, is a human antiviral protein induced by interferon that recognizes viral RNA lacking host-specific 5′ modifications and blocks its translation.

IFITM3

IFITM3 (interferon-induced transmembrane protein 3, 1-8U) is a 133 amino acid type II transmembrane restriction factor on chromosome 11 that blocks viral membrane fusion in endosomes, limiting influenza, dengue, Ebola, and SARS-CoV-2 entry.

iFixit

iFixit is an American online repair community and retailer, founded in 2003 by Kyle Wiens and Luke Soules, that publishes free repair manuals and repairability scores.

IFK Göteborg

IFK Göteborg (Blåvitt), Swedish football club founded 1904 in Gothenburg; 18 Allsvenskan titles, 8 Swedish Cups, and UEFA Cup wins in 1982 and 1987; plays at Gamla Ullevi.

IFK Norrköping

IFK Norrköping (Peking), Swedish football club founded 29 May 1897 in Norrköping; 13 Swedish championships (last 2015), 6 Svenska Cupen titles; home Norrköpings Idrottspark; relegated to Superettan in 2025 after heavy financial losses.

iFlight

iFlight, full corporate name iFlight Innovation Technology Ltd. (翼飞智能科技), is a Chinese FPV drone manufacturer founded in 2014 in Huizhou, known for the Nazgul freestyle quads and its annual drone race.

Iflix

Iflix: Kuala Lumpur-based Southeast Asian streaming service founded 2015 by Catcha Group, raised $348m, peaked at 30 markets, bought by Tencent in 2020 and folded into WeTV; now a Tencent-group app for Chinese, Korean and local dramas.

iFlytek (科大讯飞)

iFlytek (科大讯飞) is a Chinese AI company founded in 1999 and listed on the Shenzhen Stock Exchange. It is known for its Spark model line and domestic compute strategy.

ifm electronic

ifm electronic is a German family-owned group headquartered in Essen, founded in 1969, that makes industrial sensors, controllers, and software for automation, employing over 9,000 people.

IFNA2

IFNA2 (interferon alpha 2, Gene ID 3440) is a single-exon human gene at 9p21.3 encoding IFN-α2, the prototypic type I interferon; recombinant IFNα2a/2b (Roferon-A, Intron A) treat leukemia and viral hepatitis.

IFNAR1

IFNAR1 (interferon alpha/beta receptor 1, UniProt P17181) is the low-affinity subunit of the human type I interferon receptor with IFNAR2, signaling via TYK2/JAK1-STAT; targeted by anifrolumab for lupus.

IFNAR2

IFNAR2 (interferon alpha and beta receptor subunit 2, gene ID 3455, 21q22.11) encodes the primary ligand-binding chain of the human type I interferon receptor with IFNAR1, signaling via JAK1-STAT; mutations cause Immunodeficiency 45.

IFNB1

IFNB1 (interferon beta 1, IFN-beta, fibroblast interferon) is the single intronless human gene on chromosome 9p21.3 encoding type I interferon beta, which signals via IFNAR1/IFNAR2 Jak-STAT and whose recombinant products were the first MS disease-modifying therapies.

IFNfreeCOG trial

IFNfreeCOG (NCT02469012), a German trial of neurocognitive performance and emotional state in chronic hepatitis C patients on interferon-free sofosbuvir-based therapy, run by University of Wuerzburg at Burghausen with TAP, SF-36, HADS, and FIS-D measures.

IFNGR1

IFNGR1 (interferon gamma receptor 1), chromosome 6q23.3, encodes the ligand-binding chain of the IFN-γ receptor; mutations cause Mendelian susceptibility to mycobacterial disease, autosomal recessive or dominant.

Ifni War

The Ifni War, which Spanish historians call the Forgotten War, was fought from late 1957 to mid-1958 between Spain and Moroccan irregular forces over the enclave of Ifni.

IFNL3

IFNL3 (formerly IL28B) is a human gene on chromosome 19q13.2 encoding interferon-lambda 3, a type III interferon. Variants near it, notably rs12979860 and rs8099917, strongly predict hepatitis C clearance and interferon-based treatment response.

IFNL4

IFNL4 (interferon lambda 4 gene, chromosome 19q13.13) encodes IFN-λ4, a type III interferon produced only in carriers of the ΔG allele of rs368234815; discovered 2013, it impairs hepatitis C virus clearance, unlike the protective TT frameshift allele.

iFood

iFood is a Brazilian online food-delivery platform founded in São Paulo in 2011, the largest in Latin America and wholly owned by Prosus since 2022.

Ifor Samuel

Ifor Samuel is a physicist and Professor of Physics at the University of St Andrews since 2000, where he founded and directs the Organic Semiconductor Centre.

Ifosfamide

Ifosfamide is an intravenous chemotherapy drug of the oxazaphosphorine class, a structural isomer of cyclophosphamide introduced in 1967, used against sarcoma, lymphoma, testicular cancer, and lung and ovarian cancers.

Ifosfamide/doxorubicin regimen

The ifosfamide/doxorubicin (ID, or Dox-Ifos) regimen is a combination chemotherapy pairing ifosfamide with doxorubicin, given in 21-day cycles mainly to treat soft-tissue sarcomas, including rhabdomyosarcoma.

Ifremer

Ifremer, the French Research Institute for Exploitation of the Sea, is a public oceanographic research institute founded in 1984 that operates France's fleet of 17 research vessels.

Ifriqiya (إفريقية)

Ifriqiya (إفريقية) was the medieval Arabic name for a North African province covering modern Tunisia, eastern Algeria, and western Libya, lasting until the Ottoman conquest in 1574.

Ifrit (عفريت)

Ifrit (ʿifrīt, عفريت): a powerful, cunning, rebellious jinn in Islamic lore, not a separate species. Named once in the Quran (27:39, Solomon's court), graded below or above marid depending on the source.