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Lethal congenital contracture syndrome type 1

Lethal congenital contracture syndrome type 1 (LCCS1, Herva disease) is a Finnish autosomal recessive arthrogryposis caused by GLE1 mutations, causing fetal akinesia, hydrops, and prenatal death before 32 weeks.

Lethal congenital contracture syndrome type 2

LCCS2, also called multiple contracture syndrome Israeli-Bedouin type, is a rare autosomal recessive arthrogryposis caused by ERBB3 mutations on 12q13, marked by congenital contractures, neurogenic megacystis, and neonatal lethality.

Lethal congenital contracture syndrome type 3

Lethal congenital contracture syndrome type 3 (LCCS3, OMIM 611369) is an ultra-rare autosomal recessive arthrogryposis caused by PIP5K1C loss-of-function variants, like LCCS2 but without neurogenic bladder, lethal perinatally from respiratory insufficiency.

Lethal dose

Lethal dose (LD50, median lethal dose): the single dose killing 50 percent of test animals, introduced by J. W. Trevan in 1927; basis of GHS acute toxicity classes and replaced by OECD tests 420, 423, and 425.

Lethal infantile mitochondrial myopathy

Lethal infantile mitochondrial myopathy (LIMM, LIMD; OMIM 551000) is a rare mtDNA-related oxidative phosphorylation disorder causing neonatal hypotonia, ophthalmoplegia, severe lactic acidosis, and death days to months after birth.

Lethal injection

Lethal injection is an execution method using intravenous drugs, first used in Texas in 1982 and now the default method in nearly all US death penalty jurisdictions.

Lethal Injection (album)

Lethal Injection, Ice Cube's fourth studio album (December 7, 1993, Priority Records), is a G-funk-era West Coast rap record co-produced with QDIII, featuring George Clinton on the 11-minute Bop Gun and the singles You Know How We Do It and Really Doe.

Lethal multiple pterygium syndrome

Lethal multiple pterygium syndrome (LMPS, OMIM 253290) is a rare autosomal recessive fetal disorder with multiple skin webs, severe arthrogryposis, hydrops, and death before or shortly after birth; CHRNG is the main gene.

Lethal omphalocele-cleft palate syndrome

Lethal omphalocele-cleft palate syndrome (OMIM 258320, ORPHA:2736) is an autosomal recessive multiple congenital anomaly disorder combining omphalocele and cleft palate, lethal in infancy, with fewer than a handful of reported cases worldwide.

Lethal Weapon

Lethal Weapon (1987) is a Richard Donner action film from Shane Black's first produced screenplay, starring Mel Gibson and Danny Glover as Vietnam-veteran L.A. cop partners; it grossed about $64 million domestically and spawned three sequels.

Lethal Weapon (franchise)

Lethal Weapon, Warner Bros. buddy cop action franchise (1987–1998): four Richard Donner films starring Mel Gibson and Danny Glover as Riggs and Murtaugh, $952.6M worldwide, plus a 2016–2019 Fox TV series and a stalled fifth film.

Lethal Weapon (TV series)

Lethal Weapon is Fox's 2016-2019 buddy-cop TV reboot of Shane Black's 1987 film franchise, created by Matt Miller, starring Damon Wayans as Murtaugh, Clayne Crawford and later Seann William Scott as his partners, canceled after three seasons in May 2019.

Lethal Weapon 2

Lethal Weapon 2 is a 1989 American buddy cop action comedy directed by Richard Donner, starring Mel Gibson and Danny Glover as detectives against South African smugglers.

Lethal Weapon 3

Lethal Weapon 3, also known as Lethal Weapon III, is a 1992 American buddy cop action comedy film directed by Richard Donner, starring Mel Gibson and Danny Glover.

Lethal Weapon 4

Lethal Weapon 4 is a 1998 American action film directed by Richard Donner. It stars Mel Gibson and Danny Glover as detectives Martin Riggs and Roger Murtaugh.

Lethal White

Lethal White is the fourth Cormoran Strike crime novel by Robert Galbraith (J.K. Rowling), published 18 September 2018 by Sphere; set in London during the 2012 Olympics, it follows a blackmail case and a childhood murder memory, adapted for BBC One in 2020.

Lethal white syndrome

Lethal white syndrome, or overo lethal white syndrome, is a genetic disease of horses in which white foals are born with a nonfunctional intestine and die within days.

Lethbridge

Lethbridge, Alberta, also called Coalbanks or Sikoohkotoki, is a southern Alberta city on the Oldman River; founded on 1870s coal mining, named for William Lethbridge, a city since 1906, population about 106,550 in 2023.

Lethe

Lethe (Λήθη), Greek personification of forgetfulness, daughter of Eris in Hesiod, and the underworld river whose waters the dead drank to forget their earthly lives; distinct from the Leto of Apollo's birth myth and from modern software named Lethe.

Lethe Vallis

Lethe Vallis is a roughly 230 km-long, 1.5 km-wide outflow channel in Elysium Planitia, Mars, draining Cerberus Palus eastward; named for an Alaskan river in 2006, it shows flood landforms, fluvial dunes, and lava overprints.

Lethwei

Lethwei, or Burmese boxing (လက်ဝှေ့), is a bareknuckle full-contact combat sport from Myanmar where headbutts are legal and traditional fights are won only by knockout.

Letian Dou

Letian Dou is a materials chemist and chemical engineer known for hybrid organic-inorganic perovskites (OSiPs), Paul & Phyllis Fireman Professor of Chemistry at Emory University since 2025 after Purdue.

Leticia Castillo

Leticia Castillo is an American politician and Republican member of the California State Assembly, elected in 2024 to represent the 58th district, which includes Riverside, Corona, and Eastvale.

Leticia Cugliandolo

Leticia Cugliandolo, born 1965 in Argentina, is an Argentine statistical physicist at Sorbonne Université in Paris, known for aging and effective temperature in glassy systems.

Leticia González (theoretical chemist)

Leticia González, born 1971 in Madrid, is a Spanish theoretical chemist and professor at the University of Vienna, best known for developing the SHARC surface-hopping method for photochemistry.

Leticia Gutierrez

Leticia Gutierrez is an American Democratic politician and first-time candidate, nominated for the U.S. House in Texas's 9th district in 2026 after living there for 45 years.

Leticia Incident

The Leticia Incident (Leticia Conflict) was an armed dispute between Colombia and Peru, starting in 1932, following the seizure of the Colombian Amazon River port of Leticia.

Leticia Ramírez Amaya

Leticia Ramírez Amaya is a Mexican politician and former primary school teacher affiliated with Morena, serving as Secretary of Welfare since 2026 after leading public education.

Letitia de Jong

Letitia de Jong, born 1993 in Veenwouden, is a Dutch sprint speed skater, twice world team sprint champion (2019, 2020) and holder of the 1:24.02 team sprint world record with Kok and Leerdam.

Letitia Dean

Letitia Dean is an English actress best known for playing Sharon Watts in the BBC soap opera EastEnders, winning the British Soap Award for Outstanding Achievement in 2022.