All articles starting with M
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Major Arcana
The Major Arcana are the 22 numbered trump cards of the 78-card tarot deck, from The Fool to The World, originally a Renaissance Italian card game section, later renamed by Eliphas Levi and adopted for occult divination.
Major Arena Soccer League
Major Arena Soccer League (MASL), North American professional indoor soccer league formed in 2014 from PASL and MISL teams; awards the Ron Newman Cup, plays a winter schedule, and runs MASL2, MASL3 and MASLW tiers.
Major Barbara
Major Barbara is a 1905 social satire by George Bernard Shaw in which a Salvation Army major confronts her munitions-manufacturer father over tainted charity money.
Major capsid protein VP1
Major capsid protein VP1: outer-surface capsid protein of polyomaviruses (360 copies, 72 pentamers, ~50 nm, glycan receptor binding, VLP platform), also the name for major capsid proteins of picornaviruses, norovirus, sapovirus, and AAV VP1.
Major Crimes (TV series)
Major Crimes is a TNT police procedural (2012–2018), a spin-off of The Closer created by James Duff, starring Mary McDonnell as Captain Sharon Raydor leading the LAPD Major Crimes Division; six seasons, 105 episodes, plea-deal-driven cases.
Major Crimes Act
The Major Crimes Act is a United States federal statute, enacted March 3, 1885, that places serious crimes committed by Indians in Indian country under exclusive federal jurisdiction.
Major Dad
Major Dad is a CBS family sitcom (1989-1993, 96 episodes) starring Gerald McRaney as Marine Major John MacGillis, who marries liberal reporter Polly Cooper (Shanna Reed) and her three daughters; created by Richard C. Okie and John G. Stephens.
Major depressive disorder
Major depressive disorder (MDD, clinical depression): a DSM-5-defined mood disorder of two-week depressive episodes. Formerly melancholia; affects 8.3% of US adults yearly; treated with psychotherapy, antidepressants, ECT, esketamine.
Major depressive episode
Major depressive episode: a period of at least two weeks with depressed mood or anhedonia plus five of nine DSM-5 symptoms causing impairment; basis of major depressive disorder, near-identical in ICD-11.
Major Dundee
Major Dundee is Sam Peckinpah's 1965 Civil War Western starring Charlton Heston and Richard Harris, a Union officer leading Confederate prisoners into Mexico against Apaches; famously cut from about 164 to 124 minutes and partially restored in 2005.
Major facilitator superfamily
The major facilitator superfamily (MFS) is the largest characterized superfamily of secondary membrane transport proteins, moving sugars, amino acids, and drugs using chemiosmotic ion gradients.
Major film studios
Major film studios are the dominant Hollywood financiers, producers, and distributors of films, historically the Big Five and Little Three of the studio era, now Disney, Universal, Sony, and the Paramount Warner Bros. Skydance combination.
Major Garrett
Major Elliott Garrett (born 1962, San Diego) is CBS News' chief Washington correspondent since 2018, former chief White House correspondent for CBS, Fox News, CNN, and National Journal, host of The Takeout, and author of five books.
Major general
Major general is a two-star general officer rank (US pay grade O-8, NATO OF-7) between brigadier and lieutenant general, equivalent to rear admiral, typically commanding a division; derived from sergeant major general.
Major general (United States)
Major general is the two-star U.S. general officer grade at pay grade O-8 in the Army, Air Force, and Marine Corps, equivalent to rear admiral, NATO OF-7, typically commanding a division.
Major general (میجر جنرل) (Pakistan)
Major general (میجر جنرل) is the two-star, first general officer rank of the Pakistan Army (OF-7, BPS-21), equivalent to Rear Admiral or Air Vice Marshal, typically commanding a division.
Major Greenwood
Major Greenwood (1880–1949) was an English epidemiologist and statistician, the foremost medical statistician in the United Kingdom in the first half of the twentieth century.
Major histocompatibility complex
Major histocompatibility complex (MHC; HLA in humans, chromosome 6p): gene region encoding class I and II antigen-presenting proteins, the most polymorphic loci in the genome, central to transplant rejection and immune recognition.
Major intrinsic protein
Major intrinsic protein (MIP, aquaporin-0/AQP0) is the dominant water channel of eye lens fiber cells, about 40% of their membrane protein; its deficiency causes cataracts and it archetypes the aquaporin/MIP superfamily.
Major Key (album)
Major Key is DJ Khaled's ninth studio album, released July 29, 2016 on Epic/We the Best. His first Billboard 200 No. 1 (95,000 units), Grammy-nominated for Best Rap Album, featuring Jay Z, Drake, Nas, and Kendrick Lamar.
Major Lance
Major Lance (1939-1994), American Chicago soul singer on OKeh Records; hits "The Monkey Time" and "Um, Um, Um, Um, Um, Um" written by Curtis Mayfield, produced by Carl Davis; later a British Northern soul icon.
Major Lazer
Major Lazer is an electronic dancehall project formed in 2008 by Diplo and Switch, fronted by a fictional one-armed Jamaican commando; known for Guns Don't Kill People… Lazers Do, Lean On, and Cold Water.
Major Lazer (TV series)
Major Lazer is an FXX adult animated series (April 16, 2015; 11 episodes) based on Diplo's dancehall music project, following a laser-armed Jamaican superhero fighting President Whitewall in a dystopian future Jamaica.
Major League (film)
Major League (1989) is a David S. Ward sports comedy for Paramount about a Cleveland Indians owner rigging a losing roster to move the team to Miami; it grossed about $49.8 million domestically on an $11 million budget and spawned two sequels.
Major League Baseball
Major League Baseball (MLB): 30-club North American professional baseball league formed 1903 from the NL and AL; 162-game season, 12-team postseason, no salary cap, record $12.1B 2024 revenue, Commissioner-led governance with MLBPA collective bargaining.
Major League Baseball All-Century Team
The 1999 MLB All-Century Team, or Team of the Century: 30 greatest 20th-century players chosen by fan vote plus panel additions, honored at Turner Field; Rose elected, Clemente omitted.
Major League Baseball All-Star Game
MLB All-Star Game (Midsummer Classic): annual AL vs NL exhibition since July 6, 1933 at Comiskey Park, created by Arch Ward; AL leads 48-45-3; swing-off tiebreaker first used 2025.
Major League Baseball blackout policy
Major League Baseball blackout policy: rules blacking out MLB.TV and Extra Innings games in home television territories and on national exclusive broadcasts; enforced by IP geo-location, challenged in antitrust court, relaxed for 22 of 30 clubs in 2026.
Major League Baseball draft
MLB draft (Rule 4 draft), annual amateur player draft held since June 8, 1965; reverse-standing order, 20 rounds, bonus pools since 2012, top-six lottery since 2023; Rick Monday first pick, 54 drafted Hall of Famers.
Major League Baseball Most Valuable Player Award
MLB Most Valuable Player Award: BBWAA-voted annual honor, one per league since 1931, after the Chalmers Award (1911-14) and League Award (1922-29). 30 voters per league, 14-9-...-1 scoring; Bonds won a record 7.