All articles starting with M

Muchinga Province

Muchinga Province is one of Zambia's ten provinces, in the northeast, created in 2011 from Northern Province. Smallest provincial population (918,296 in 2022); capital Chinsali; known for maize growth and the TRALARD 2 climate program.

Mucilage

Mucilage: gel-like plant polysaccharide secreted by seed coats, pericarps, and roots; swells into a hydrogel on hydration. Found in over 80 angiosperm families; aids dispersal, germination, and stress protection, and is used in films, coatings, and drug delivery.

Mucin

Mucins are heavily O-glycosylated glycoproteins (over 50% glycan by mass) forming mucus and the glycocalyx; types include gel-forming MUC2, soluble, and transmembrane mucins protecting epithelia.

Mucin-like domain

Mucin-like domain (PTS domain, O-glycodomain): a proline, serine, threonine-rich protein region, often tandem repeats, densely modified with O-GalNAc glycans by GALNT enzymes in the Golgi, giving mucins their extended bottle-brush shape.

Mucinous adenocarcinoma of ovary

Mucinous adenocarcinoma of ovary (ovarian mucinous adenocarcinoma, MOC), a rare 3–5% subtype of epithelial ovarian cancer; unilateral mucin-producing tumor, good early-stage prognosis, poor advanced-stage survival, expansile versus infiltrative WHO subtypes.

Mucinous cystadenocarcinoma of the pancreas

Mucinous cystadenocarcinoma of the pancreas (MCAC), also called pancreatic mucinous cystic neoplasm with associated invasive carcinoma, is the malignant grade of mucinous cystic neoplasm, arising almost exclusively in middle-aged women in the pancreatic body or tail, with about 60% five-year survival after resection.

Mucize Doktor

Mucize Doktor (Miracle Doctor) is the Turkish adaptation of South Korea's 2013 Good Doctor, aired on FOX/NOW 2019-2021, 64 episodes, starring Taner Ölmez as autistic savant surgeon Dr. Ali Vefa at Berhayat Hospital.

Muckle-Wells syndrome

Muckle-Wells syndrome (MWS), an intermediate cryopyrinopathy within CAPS, is an autosomal dominant NLRP3-related autoinflammatory disease causing urticarial rash, recurrent fever, sensorineural hearing loss, and AA amyloidosis, treatable with IL-1 inhibitors.

Muckleshoot

The Muckleshoot (bəqəlšuł) are a federally recognized Washington tribe of Duwamish and Upper Puyallup descent, holding rights under the 1854 Medicine Creek and 1855 Point Elliott treaties, with an 1857 reservation near Auburn and the 1974 Boldt fishing-rights ruling.

Muckraker

Muckraker: term coined by Theodore Roosevelt in 1906 for Progressive Era investigative journalists like Tarbell, Steffens, and Sinclair who exposed corruption and spurred reform.

Oct 22, 2026

Muckraking novel

A muckraking novel is a work of fiction that exposes social, economic, or political evils through investigative journalism, a Progressive Era form exemplified by Upton Sinclair's 1906 novel The Jungle.

Mucocele of appendix

Mucocele of appendix (appendiceal mucocele): mucin-filled cystic dilatation of the appendix, a descriptive term covering retention cysts through LAMN, HAMN, and mucinous adenocarcinoma; rupture risks pseudomyxoma peritonei; treated by appendectomy guided by pathology.

Mucociliary Clearance

Mucociliary clearance, also called mucociliary transport, is the lung's primary innate defense: cilia beating in metachronal waves propel a mucus layer trapping inhaled particles and pathogens out of the airways.

Mucocutaneous leishmaniasis

Mucocutaneous leishmaniasis (espundia, mucosal leishmaniasis), a Leishmania sandfly-borne disease destroying nose, mouth, and throat mucosa; mainly L. braziliensis in Bolivia, Brazil, Ethiopia, Peru; treated with pentavalent antimonials.

Mucocutaneous venous malformations

Mucocutaneous venous malformations, formally VMCM, are a rare hereditary vascular malformation causing small venous lesions of the skin and mucosa, inherited in an autosomal dominant pattern.

Mucolipidosis type II

Mucolipidosis type II, or I-cell disease (MLII alpha/beta), a severe autosomal recessive lysosomal storage disorder from GNPTAB mutations causing mannose-6-phosphate tagging failure, presenting at birth with dysostosis multiplex, cardiac and respiratory disease, and death in early childhood.

Mucolipidosis type III

Mucolipidosis type III (pseudo-Hurler polydystrophy), MLIII alpha/beta (GNPTAB) or gamma (GNPTG), is a rare autosomal recessive lysosomal storage disorder from partial GlcNAc-1-phosphotransferase deficiency, causing progressive joint stiffness, short stature, and dysostosis multiplex with median survival of 62 years.

Mucolipidosis type IV

Mucolipidosis type IV (MLIV, OMIM 252650) is an ultra-rare autosomal recessive lysosomal storage disorder caused by MCOLN1 mutations, marked by psychomotor delay, progressive vision loss, achlorhydria, and a 2026 FDA-authorized gene therapy trial.

Mucolipin

Mucolipin (TRPML/MCOLN), a TRP ion channel subfamily of three endolysosomal Ca2+-permeable cation channels (TRPML1-3); TRPML1 mutations cause mucolipidosis type IV, TRPML2 is immune-cell specific.

Oct 22, 2026

Muconic acid

Muconic acid is an unsaturated dicarboxylic acid with three stereoisomers, produced by fermentation from biomass and valued as a renewable route to adipic acid, the nylon precursor.

Oct 22, 2026

Mucopenetrating nanoparticles

Mucopenetrating nanoparticles (MPPs), also called mucus-penetrating particles, are drug carriers whose dense PEG coating makes them muco-inert, allowing them to diffuse through mucus instead of being trapped by it.

Mucopolysaccharidosis

Mucopolysaccharidosis (MPS), also called mucopolysaccharidoses, is a group of rare inherited lysosomal storage diseases in which enzyme deficiency causes glycosaminoglycan buildup; types include Hurler, Hunter, Sanfilippo, and Morquio syndromes, treated with ERT, HSCT, and gene therapy.

Mucopolysaccharidosis type 1

Mucopolysaccharidosis type 1 (MPS I, Hurler syndrome, alpha-L-iduronidase deficiency) is a rare autosomal recessive lysosomal storage disorder causing dermatan and heparan sulfate accumulation, treated with HSCT and laronidase enzyme replacement therapy.

Mucopolysaccharidosis type 10

Mucopolysaccharidosis type 10 (MPS10, MPS type X, ARSK deficiency) is an autosomal recessive lysosomal storage disorder from biallelic ARSK variants on 5q15, causing childhood short-trunk short stature with skeletal, cardiac, and ophthalmologic findings but normal cognition.