All articles starting with M
36,687 articles
MDA-MB-468
MDA-MB-468 (ATCC HTB-132, CVCL_0419) is a human triple-negative, basal-like breast cancer cell line isolated in 1977 from a pleural effusion of a 51-year-old Black female donor, carrying TP53 R273H, PTEN loss, and amplified EGFR.
MDABCO ammonium perovskite
MDABCO ammonium perovskite is a metal-free all-organic perovskite ferroelectric, reported in Science in 2018, with a polarization of 22 μC cm⁻² near that of barium titanate.
mdadm
mdadm is the standard Linux command-line tool for managing MD devices, the kernel's software RAID, which combines disks into virtual block devices, some with redundancy against disk failure.
Mdantsane
Mdantsane: large township in Buffalo City, Eastern Cape, South Africa, between East London and King William's Town. Established 1962-1963 as a Ciskei dormitory township; second largest township after Soweto; 156,835 residents (2011); 18 numbered zones; isiXhosa-speaking.
MDBK
MDBK (Madin-Darby Bovine Kidney, NBL-1, ATCC CCL-22) is a bovine kidney epithelial cell line established in 1957 by Madin and Darby, widely used for propagating bovine viruses and as a transfection host.
Mdc Capital Partners
MDC Capital Partners is a venture capital investment platform based in Abu Dhabi, UAE, investing in North American technology companies through a 2017 fund within the Mubadala group.
MDC1
MDC1 (NFBD1, mediator of DNA damage checkpoint 1) is a 2,089-residue human scaffold protein that binds γH2AX at DNA double-strand breaks, amplifies ATM signaling, recruits repair factors like 53BP1 and BRCA1, and acts as a tumor suppressor and nuclear receptor co-regulator.
MDCK
MDCK, short for Madin-Darby Canine Kidney, is a dog kidney cell line established in 1958 that is the standard model for epithelial polarity and a substrate for influenza vaccines.
MDF (file format)
MDF, or Measurement Data Format, is a binary file format standardized by ASAM e.V. that stores recorded measurement data, serving as the de facto standard in the automotive industry.
MDH (spice company)
MDH (Mahashian Di Hatti Private Limited) is India's second-biggest packaged spice company after Everest, founded in 1919 in Sialkot and rebuilt in Delhi after Partition; known for 62 masala blends, the 'Dadaji' ads, and 2024 ethylene oxide export scrutiny.
Mdina
Mdina (L-Imdina), Malta's Silent City, also called Città Vecchia or Città Notabile, is a fortified hill-top city and the island's old capital from antiquity until 1530, with Bronze Age origins, Arab-era winding streets, and 18th-century Baroque architecture.
Mdina steles
The Mdina steles are two Phoenician votive inscriptions from Malta, found near Rabat-Mdina in 1870, dedicated to Baal-Hammon, and known as KAI 61 and CIS I 123.
MDL (programming language)
MDL, originally named Muddle, is a strongly typed Lisp dialect created at MIT in 1970, best known as the language of the original mainframe Zork.
Mdm2
Mdm2 (double minute 2, Hdm2) is a RING E3 ubiquitin ligase and the main negative regulator of p53, binding its transactivation domain and driving its degradation; amplified in cancers and targeted by inhibitors such as brigimadlin and milademetan.
MDM4
MDM4 (MDMX, HDMX), gene ID 4194 at 1q32, encodes a 490-aa p53 negative regulator that heterodimerizes with MDM2 to drive p53 ubiquitination and has p53-independent roles in DNA repair and replication; overexpressed in about 20% of cancers.
MDMA
MDMA (Ecstasy, Molly), 3,4-methylenedioxymethamphetamine, is a synthetic empathogen-stimulant releasing serotonin, dopamine, and norepinephrine; Schedule I in the US since 1985; FDA rejected MDMA-assisted PTSD therapy in 2024.
MDMA-assisted psychotherapy
MDMA-assisted psychotherapy (MDMA-AT, midomafetamine) is an experimental PTSD treatment pairing supervised MDMA sessions with structured therapy; Phase 3 trials showed benefit, but the FDA declined approval in August 2024.
MDN2-binding protein
MDN2-binding protein (MDM2-binding protein, MTBP) is a nuclear protein that binds MDM2, drives DNA replication origin firing with Treslin/TICRR, acts as a MYC cofactor, and is overexpressed in cancers including triple negative breast cancer.
MDNA (album)
MDNA is Madonna's twelfth studio album, released March 2012 on Interscope/Live Nation, her first outside Warner Bros. Produced by William Orbit, Martin Solveig and the Benassi brothers, it scored 64 on Metacritic and supported the lucrative MDNA Tour.
Mdou Moctar
Mdou Moctar (Mahamadou Souleymane) is a Tuareg guitarist and songwriter from Agadez, Niger, known for left-handed psychedelic desert blues, the viral Bluetooth-spread album Anar, the Tuareg-language film Akounak, and Matador albums Afrique Victime and Funeral for Justice.
MDPI
MDPI (Multidisciplinary Digital Publishing Institute), formerly Molecular Diversity Preservation International, is a Basel-based open-access journal publisher founded in 1996 by Shu-Kun Lin, running about 500 APC-funded journals and debated over special-issue practices.
MDR-001
MDR-001: MindRank's AI-designed oral small-molecule GLP-1 receptor agonist (β-arrestin2-biased) for obesity and type 2 diabetes; Phase 2b showed 8-10% weight loss; Phase III MOBILE trial ongoing in China.
MDX (MultiDimensional eXpressions)
MDX (MultiDimensional eXpressions), the OLAP query language from Microsoft defined in OLE DB for OLAP, queries cubes via SELECT/FROM/WHERE; used by Analysis Services, SAP, and Essbase, distinct from DAX.
mdx mouse
The mdx mouse is a mutant laboratory mouse lacking the muscle protein dystrophin, the standard animal model of Duchenne muscular dystrophy, arising spontaneously in 1981 and described in 1984.
Me Against the World
Me Against the World (1995) is 2Pac's third studio album, released on Interscope March 14, 1995 while he was in prison; it debuted at number one on the Billboard 200, went 2X Platinum, and features "Dear Mama."
Me and Bobby McGee
"Me and Bobby McGee" is a song written by Kris Kristofferson and Fred Foster, first recorded by Roger Miller in 1969 and made famous by Janis Joplin's 1971 version.
Me and Earl and the Dying Girl (film)
Me and Earl and the Dying Girl is a 2015 American comedy-drama directed by Alfonso Gomez-Rejon, adapted by Jesse Andrews from his 2012 novel, starring Thomas Mann, Olivia Cooke, and RJ Cyler; it won Sundance's Grand Jury Prize and Audience Award.
Me and Julio Down by the Schoolyard
Paul Simon's 1972 solo single from the album Paul Simon; follow-up to "Mother and Child Reunion," with the Rosie/Corona chorus, cuica percussion by Airto Moreira, Dutch Top 40 peak No. 4, and reported chart positions 15 and 22.
Me and Mr. Johnson
Me and Mr. Johnson is Eric Clapton's 2004 Reprise tribute album of 14 Robert Johnson covers, produced with Simon Climie, peaking at number 10 on the UK album chart, followed by Sessions for Robert J.
Me and Mrs. Jones
Me and Mrs. Jones: 1972 soul ballad by Billy Paul, written by Gamble, Gilbert, and Huff, about a cafe love affair; three weeks at number 1 on the Billboard Hot 100 in December 1972.