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All articles starting with N

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Neonatal intensive care unit

Neonatal intensive care unit (NICU): specialized hospital unit for critically ill or preterm newborns, first established 1960 at Yale by Louis Gluck; AAP levels II–IV, US admission 9.8% of births in 2023.

Neonatal intrahepatic cholestasis due to citrin deficiency

NICCD (neonatal intrahepatic cholestasis caused by citrin deficiency) is the neonatal phenotype of autosomal recessive SLC25A13/citrin deficiency, causing cholestasis, hypercitrullinemia, and hypoglycemia in infants, treated with lactose-free MCT-enriched formula and fat-soluble vitamins.

Neonatal iodine exposure

Neonatal iodine exposure (ORPHA:238688, ICD-10 P72.2) is a rare endocrine disorder causing transient hypothyroidism, mainly in preterm newborns, after topical povidone-iodine antiseptics, iodinated contrast media, amiodarone, or maternal iodine excess, via the Wolff-Chaikoff effect.

Neonatal jaundice

Neonatal jaundice, or neonatal hyperbilirubinemia, is yellow skin and eye discoloration from bilirubin buildup in newborns, affecting over 80% of infants; treated with phototherapy or exchange transfusion to prevent kernicterus.

Neonatal listeriosis

Neonatal listeriosis is newborn infection with Listeria monocytogenes, usually acquired in utero, presenting as early-onset sepsis or pneumonia or late-onset meningitis, rare but with high mortality and disability risk.

Neonatal lupus erythematosus

Neonatal lupus erythematosus, or neonatal lupus, is an autoimmune condition of fetuses and newborns caused by maternal anti-Ro antibodies crossing the placenta, causing rash and heart block.

Neonatal maladjustment syndrome

Neonatal maladjustment syndrome (NMS), also called dummy foal syndrome or neonatal encephalopathy, is a noninfectious neurologic disorder of newborn foals affecting 1-2% of births, treated supportively and with the Madigan Squeeze Technique.

Neonatal meningitis

Neonatal meningitis: bacterial infection of the meninges and CSF in newborns (first 28 days, often considered to 90 days). Caused mainly by GBS, E. coli, Listeria; fatality 10–15% in high-income versus 40–58% in low-income settings.

Neonatal milia

Neonatal milia (milk spots) are benign keratin-filled white cysts present at birth in 40-50% of full-term newborns, mainly on the nose and face, resolving spontaneously within weeks without treatment; oral forms are Epstein pearls and Bohn nodules.

Neonatal miliaria

Neonatal miliaria, or heat rash, is a benign newborn rash from blocked eccrine sweat ducts; types include crystallina (clear 1–2 mm vesicles, up to 9% of neonates), rubra, and pustulosa; self-limiting with cooling.

Neonatal necrotising fasciitis

Neonatal necrotising fasciitis (ICD-11 1B71.2) is a rare, life-threatening bacterial infection of fascia, subcutaneous tissue, and skin in newborns, usually secondary to omphalitis, historically fatal in about 59% of cases but with mortality near 20-24% in recent series.

Neonatal peritonitis

Neonatal peritonitis (ICD-11 KB8B) is acute peritoneal inflammation in newborns 0-28 days, usually from intestinal perforation, NEC, or obstruction; bacterial or chemical, with high mortality and ampicillin-gentamicin-clindamycin empiric therapy.

Neonatal renal venous thrombosis

Neonatal renal venous thrombosis (RVT, NRVT): blood clot in a newborn's renal vein within 28 days of life, the most common spontaneous neonatal venous thrombosis; triad of flank mass, hematuria, thrombocytopenia; high long-term kidney risk.

Neonatal resuscitation

Neonatal resuscitation is the emergency care given to newborns who fail to breathe at birth, from ventilation within the first minute to chest compressions and epinephrine.

Neonatal scleroderma

Neonatal scleroderma (ORPHA:398127) is a rare secondary neonatal autoimmune disease with linear erythematous lesions that become indurated, hyperpigmented, and atrophic; prevalence under 1 per million, ICD-10 P83.8.

Neonatal seizures

Neonatal seizures: seizures in newborns (first 28 days, up to 44 weeks PMA), 1–5 per 1000 live births, mostly acute provoked by HIE, stroke, infection; diagnosed by EEG; phenobarbital first-line.

Neonatal severe primary hyperparathyroidism

Neonatal severe primary hyperparathyroidism (NSHPT, NHPT; ORPHA:417, OMIM 239200) is a rare autosomal recessive disorder, usually from homozygous CASR loss-of-function mutations, causing severe hypercalcemia (>3.5 mM), bone demineralization, and failure to thrive from birth; often fatal without parathyroidectomy.

Neonatal stroke

Neonatal stroke (neonatal arterial ischemic stroke, NAIS) is focal brain infarction from arterial or venous occlusion within 28 days of birth; seizures are the typical presentation, MRI with DWI the diagnostic standard, and treatment mainly supportive.

Neonatal toxic erythema

Neonatal toxic erythema, also called erythema toxicum neonatorum (ETN) or toxic erythema of the newborn, is a benign, self-limited rash of macules, papules, and pustules in the first days of life, affecting up to half of term newborns and resolving without treatment.

Neonatal urinary tract infection

Neonatal urinary tract infection is a bacterial UTI presenting in the first 28 days after birth, more often linked with sepsis and congenital urinary anomalies.

Neonatal vitamin K deficiency

Neonatal vitamin K deficiency, or vitamin K deficiency bleeding (VKDB), formerly hemorrhagic disease of the newborn, is bleeding in infants up to 6 months old caused by low vitamin K and clotting factors; prevented by a 1 mg intramuscular shot at birth.

Neonatology

Neonatology: pediatric subspecialty for medical care of newborn infants, especially preterm and ill babies, practiced in NICUs. Covers incubators, surfactant, CPAP, resuscitation, family-centred care, and disparities.

NeOnc Technologies Holdings

NeOnc Technologies Holdings, also known as NeOnc Technologies, Inc., is a Calabasas, California clinical-stage biopharmaceutical company developing intranasal nose-to-brain therapies for central nervous system cancers.

Neonicotinoid

Neonicotinoids are synthetic nicotine-related systemic insecticides acting on insect nicotinic acetylcholine receptors; imidacloprid (1991, Shinzo Kagabu) began the class, now the world's most used insecticides, restricted in the EU over bee risks.

Neopanamax

Neopanamax is the size class of ships that fit through the Panama Canal's third set of locks, opened in June 2016, far larger than the older Panamax limit.

Neopentane

Neopentane, also called 2,2-dimethylpropane or tetramethylmethane, is the most branched pentane isomer, a C₅H₁₂ hydrocarbon with a central carbon bonded to four methyl groups that boils at 9.5 °C and is a gas at room temperature.

Neopentyl glycol

Neopentyl glycol (NPG, 2,2-dimethylpropane-1,3-diol) is a white crystalline diol used as a building block for polyester, polyurethane, and alkyd resins, synthetic lubricants, and plasticizers, whose quaternary carbon gives polymers high hydrolytic stability and weather resistance.

Neopets

Neopets is a free virtual pet browser game launched in 1999 by Adam Powell and Donna Williams, set in Neopia, with Neopoints, mini-games, over 150 million players, and owners including Viacom, JumpStart, and NetDragon.

Neophobia

Neophobia is fear or avoidance of novel stimuli; food neophobia is reluctance to try unfamiliar foods, measured by the Pliner and Hobden Food Neophobia Scale, peaking at ages 2 to 6 and linked to poorer diet quality.

Neophocaena

Neophocaena, finless porpoises, genus of dorsal-fin-less porpoises (Phocoenidae) with two species, Indo-Pacific N. phocaenoides and narrow-ridged N. asiaeorientalis, including the critically endangered freshwater Yangtze finless porpoise.