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All articles starting with S

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Seventh-inning stretch

Seventh-inning stretch, a baseball tradition of fans rising and singing during the middle of the seventh inning; origins disputed (1869 Harry Wright letter, 1882 Brother Jasper, 1910 Taft), with "Take Me Out to the Ball Game" popularized by Harry Caray and Bill Veeck in Chicago.

Seventure Partners

Seventure Partners is a European venture capital firm founded in 1997 and headquartered in Paris, investing in life sciences and digital technology, with microbiome-focused Health for Life funds.

Seventy-four (ship)

The seventy-four was a two-decked ship of the line carrying 74 guns, developed by France in the 1730s; it became the backbone of British, French, and Spanish battle fleets.

Sever's disease

Sever's disease (calcaneal apophysitis) is inflammation of the heel growth plate in children aged about 8 to 15, caused by Achilles tendon traction during growth spurts; self-limiting, treated with rest, orthoses, and stretching.

Severan dynasty

The Severan dynasty, also known as the Severan period, was the line of Roman emperors who ruled from 193 to 235, founded by Septimius Severus and ended by the assassination of Severus Alexander.

Severance (novel)

Severance is Ling Ma's 2018 debut novel (FSG), a satirical zombie-apocalypse story in which immune office worker Candace Chen survives the Shen Fever pandemic. It won the Kirkus Prize and NYPL Young Lions Award and is unrelated to the Apple TV+ series of the same name.

Severance (TV series)

Severance is an Apple TV+ workplace science-fiction thriller created by Dan Erickson, directed and produced by Ben Stiller, starring Adam Scott as Mark Scout at Lumon Industries, whose employees' memories are surgically split between work and personal lives; premiered February 18, 2022, renewed for season 3 with filming underway since July 2026.

Severance Hospital

Severance Hospital (세브란스병원), Yonsei University's teaching hospital in Seoul, descends from Gwanghyewon/Chejungwon, Korea's first Western-style hospital, founded 1885 by Dr. H.N. Allen and renamed after donor Louis H. Severance in 1904.

Severance package

Severance package: payments and benefits given when employment ends, also called redundancy or termination pay. Covers statutory scales (Australia, Thailand, Ontario), US at-will voluntariness, OWBPA waiver rules, and economic rationale.

Severe accident management

Severe accident management is the set of actions during a nuclear power plant accident to prevent escalation, mitigate a severe accident's consequences, and achieve a safe stable state.

Severe achondroplasia-developmental delay-acanthosis nigricans syndrome

SADDAN (severe achondroplasia-developmental delay-acanthosis nigricans syndrome; skeleton-skin-brain syndrome) is an ultra-rare FGFR3 skeletal dysplasia caused by p.Lys650Met, with severe short stature, seizures, and skin changes.

Severe acute malnutrition

Severe acute malnutrition is the most dangerous form of child undernutrition, diagnosed in children aged 6 to 59 months by very low weight for height, arm circumference below 115 mm, or edema.

Severe birth asphyxia

Severe birth asphyxia (重症新生児仮死), ICD-11 KB21.0 / ICD-10 P21.0: newborn fails to breathe at birth with pulse under 100, gasping, poor colour, absent tone; about 900,000 deaths yearly.

Severe combined immunodeficiency

Severe combined immunodeficiency (SCID), or bubble boy disease, is a rare inherited immune disorder with defective T and B cells, fatal by age two untreated; caused by IL2RG, ADA, and other gene mutations, detected by TREC newborn screening, treated by transplant or gene therapy.

Severe congenital nemaline myopathy

Severe congenital nemaline myopathy, the most severe form of nemaline myopathy, causes neonatal hypotonia, feeding difficulty, and respiratory failure; usually autosomal recessive, linked to ACTA1 and NEB genes, and rarely survived past infancy.

Severe dengue

Severe dengue is the life-threatening form of dengue virus infection, defined by WHO 2009 criteria as severe plasma leakage with shock, severe bleeding, or severe organ involvement; secondary infection raises risk, and prompt IV fluids cut fatality below 0.5%.

Severe dermatitis-multiple allergies-metabolic wasting syndrome

SAM syndrome (OMIM 615508), also called congenital erythroderma-hypotrichosis-recurrent infections-multiple food allergies syndrome, is a rare genodermatosis caused by DSG1 or DSP desmosomal gene mutations, featuring congenital erythroderma, severe dermatitis, elevated IgE, food allergies, and metabolic wasting.

Severe early-childhood-onset retinal dystrophy

Severe early-childhood-onset retinal dystrophy (SECORD), also called early-onset severe retinal dystrophy (EOSRD), is an inherited retinal dystrophy with night blindness, nystagmus, and progressive vision loss beginning before age 5.

Severe early-onset pulmonary alveolar proteinosis due to MARS deficiency

Severe early-onset pulmonary alveolar proteinosis due to MARS deficiency, also called interstitial lung and liver disease (ILLD, OMIM 615486): autosomal recessive MARS1 methionyl-tRNA synthetase deficiency causing infantile alveolar lipoprotein accumulation, respiratory failure, liver disease, first described 2013 on Réunion Island.

Severe fever with thrombocytopenia syndrome

Severe fever with thrombocytopenia syndrome (SFTS), caused by Dabie bandavirus (SFTSV), is a tick-borne zoonosis of East Asia transmitted mainly by Haemaphysalis longicornis, with about 19,000 Chinese cases 2011-2021, case fatality 5-30%, and no approved vaccine.

Severe generalized junctional epidermolysis bullosa (Herlitz type)

Severe generalized junctional epidermolysis bullosa, formerly the Herlitz type, is an inherited disease in which loss of laminin 332 causes widespread blistering from birth, usually fatal within two years.

Severe inflammatory acne

Severe inflammatory acne (ICD-11 ED80.4) is intensely inflammatory acne, acute acne fulminans or chronic acne conglobata, defined by nodules, cysts, and scarring, treated with isotretinoin, doxycycline, and intralesional corticosteroids.

Severe intellectual disability and progressive spastic paraplegia

Severe intellectual disability and progressive spastic paraplegia, now called AP-4 deficiency syndrome, is a rare autosomal recessive hereditary spastic paraplegia causing developmental delay, severe intellectual disability, and progressive spasticity.

Severe plastic deformation

Severe plastic deformation (SPD) is a family of metal-forming techniques that impose very large strains on bulk metals without changing their dimensions, refining grains to nanometer scale for high strength.

Severe pre-eclampsia

Severe pre-eclampsia (preeclampsia with severe features) is the severe form of pregnancy hypertension after 20 weeks, defined by BP ≥160/110 mmHg, organ dysfunction, or HELLP; managed with magnesium sulfate, antihypertensives, and timed delivery.

Severe primary trimethylaminuria

Severe primary trimethylaminuria (TMAU, fish odor syndrome, ORPHA:468726) is a rare autosomal recessive FMO3-deficiency disorder causing trimethylamine buildup and fishy body odor, with no cure but dietary and supportive treatment.

Severe tropical storm

A severe tropical storm is a tropical cyclone in the western North Pacific with 10-minute winds of 48 to 64 knots, as classified by Japan.

Severe vision impairment

Severe vision impairment, WHO category 2 (ICD-10 H54.1/H54.6, ICD-11 9D90.3), is distance acuity in the better eye worse than 6/60 but 3/60 or better, between moderate impairment and blindness.

Severe weather

Severe weather, also called bad weather, is any hazardous atmospheric event threatening life or property, most commonly a thunderstorm with a tornado, large hail, or 58 mph winds.

Severe weather terminology (United States)

Severe weather terminology in the United States is the National Weather Service's tiered system of outlooks, watches, advisories, and warnings, with warnings issued when hazardous weather is imminent.