All articles starting with S
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Silyl protection of thiols, carboxylic acids and other heteroatoms
Silyl protection of thiols, carboxylic acids, and other heteroatoms uses organosilicon reagents to temporarily mask groups like amines and phosphorus functions, with removal by fluoride or hydrolysis.
Silyl radical chemistry
Silyl radical chemistry is the branch of radical chemistry concerned with silicon-centered radicals, which abstract halogens, add to unsaturated bonds, and replace toxic organotin reagents; tris(trimethylsilyl)silane is the benchmark reagent.
Silylation
Silylation is the introduction of a substituted silyl group, usually trimethylsilyl (TMS), into a molecule. It increases volatility and is used in over 80% of GC derivatization reactions.
Silyliumylidene
A silyliumylidene is a positively charged, low-valent silicon(II) cation of the form [RSi:]+, with a lone pair and two vacant orbitals, stabilized by donor ligands and known for small-molecule activation.
Silylone
A silylone is a neutral silicon(0) compound with two lone pairs at a silicon atom, stabilized by ligands such as N-heterocyclic carbenes, predicted in 2009 and first isolated in 2013.
Silymarin
Silymarin is a mixture of flavonolignans isolated from the milk thistle plant, named in 1968, used to protect liver cells; its benefit for liver disease remains uncertain.
SiM
SiM (Silence iz Mine) is a four-piece Japanese reggae punk band formed in 2004 in Shonan, Kanagawa, best known for the 2022 hit "The Rumbling" from Attack on Titan.
SIM Application Toolkit
The SIM Application Toolkit, also known as SIM Toolkit or STK, is a set of standardized commands letting SIM card applications control a phone's display, calls, and messaging.
Sim Bhullar
Sim Bhullar (Gursimran Singh Bhullar), Canadian 7'5" center born 1992 in Toronto; first player of Indian descent to sign with and play for an NBA team (Sacramento Kings, 2015), later a long pro career in Taiwan.
SIM card
A SIM card, or subscriber identity module, is a smart card that identifies a subscriber to a mobile network; the first commercial one was delivered in 1991.
Sim D. Aberson
Sim D. Aberson is an American meteorologist at NOAA's Hurricane Research Division in Miami since 1988, whose research using dropwindsondes from Hurricane Hunter aircraft improved hurricane track forecasts.
Sim Gwon Ho
Sim Gwon Ho (심권호, Sim Kwon-Ho), South Korean Greco-Roman wrestler born 1972 in Seongnam; won Olympic gold at Atlanta 1996 (48 kg) and Sydney 2000 (54 kg), two world titles, FILA Hall of Fame 2014.
Sim Iness
Sim Iness (Simeon Garland Iness, 1930-1996), American discus thrower; 1952 Helsinki Olympic gold with 55.03 m Olympic record; first man over 190 feet with 57.93 m world record in 1953.
SIM lock
A SIM lock, also called a subsidy or carrier lock, is a restriction that makes a mobile phone reject SIM cards from networks other than its original carrier.
Sim racing
Sim racing: racing video games played with wheels, pedals, and force-feedback hardware, from iRacing to Gran Turismo 7. Grew from Papyrus's 1989 Indianapolis 500 simulation into FIA-sanctioned esports with F1 Sim Racing and national championships.
Sim Seok Hui
Sim Seok Hui, also known internationally as Shim Suk-Hee, is a South Korean short track speed skater who has won three Olympic gold medals in the women's 3,000 meters relay.
SIM swap scam
SIM swap scam (SIM hijacking, SIM jacking): account-takeover fraud where an attacker impersonates a victim to a mobile carrier to transfer the victim's phone number to an attacker-controlled SIM, intercepting SMS one-time passcodes to access bank and crypto accounts; FBI IC3 logged $68 million in 2021 US losses.
Sim Ui-gyeom
Sim Ui-gyeom (심의겸, 1535–1587) was a mid-Joseon civil official serving kings Myeongjong and Seonjo, and brother of Queen Insun, whose 1575 rivalry with Kim Hyo-won founded the Eastern and Western factions.
Sim-to-real transfer
Sim-to-real transfer is the set of techniques for making robot policies trained in simulation work on physical robots, closing the reality gap caused by mismatched dynamics, sensors, and environments.
SIM0278 (IL-2 mutein Fc fusion)
SIM0278 (ALM223) is Simcere's Treg-preferential IL-2 mutein Fc fusion protein for autoimmune disease, licensed to Almirall outside Greater China, now in Phase II trials for atopic dermatitis, alopecia areata, and lupus.
SIM0500, GPRC5D/BCMA/CD3 trispecific antibody
SIM0500 is a humanized GPRC5D-BCMA-CD3 trispecific T-cell engager antibody by Simcere Zaiming for relapsed/refractory multiple myeloma, in Phase 1 trials (NCT06375044) in China and the U.S., with an AbbVie option-to-license deal worth up to $1.055 billion.
SIM0660
SIM0660 is a preclinical CD79a/CD19/CD3 tri-specific T-cell engager from Simcere Zaiming (2096.HK), licensed globally to Roche on 1 September 2026 for $75 million upfront and up to $1.53 billion total, targeting B-cell-mediated diseases.
SIM0709
SIM0709 is a preclinical, half-life-extended TL1A/IL-23p19 bispecific antibody from Simcere (先聲藥業) for inflammatory bowel disease; Boehringer Ingelheim licensed global rights outside Greater China in January 2026 for up to €1.058 billion.
SIMA 2
SIMA 2 is a generalist embodied agent by Google DeepMind, announced in November 2025, that perceives 3D virtual worlds through video and acts via keyboard and mouse.
Sima Chengzhen
Sima Chengzhen (司马承祯, 647–735) was a Tang-dynasty Daoist master of the Shangqing tradition who served as an adviser on Daoist learning to Wu Zetian and emperors Ruizong and Xuanzong.
Sima clan of Henei
The Sima clan of Henei (河內司馬氏) was a Chinese family from Henan that rose from military service to become a Confucian great family and founded the Jin dynasty.
Sima Cuo's debate on the conquest of Shu
Sima Cuo's debate on the conquest of Shu (司马错论伐蜀) was a 316 BC policy dispute at the Qin court over conquering Shu or attacking Han.
Sima de los Huesos hominins
Sima de los Huesos hominins: Middle Pleistocene humans (~450–430 ka) from the Atapuerca cave "pit of bones" in Spain, at least 29 individuals, the largest Middle Pleistocene hominin assemblage, genetically early Neanderthals with Denisovan-like mtDNA.
Sima Fa
The Sima Fa (司马法) is an ancient Chinese military classic on military rites and warfare, associated with Sima Rangju of Qi and compiled in the Warring States period.
Sima Guang
Sima Guang (司马光, 1019–1086) was a Northern Song historian and statesman who led the compilation of the Zizhi Tongjian, a monumental general history of China.