edgepedia

All articles starting with S

44,216 articles

Smith-McCort dysplasia

Smith-McCort dysplasia (SMC, OMIM 607326/615222), a rare autosomal recessive spondylo-epi-metaphyseal dysplasia with barrel chest, double-humped vertebrae, lacy iliac crests, and normal intelligence, unlike DMC; caused by DYM or RAB33B variants.

Smith–Lemli–Opitz syndrome

Smith–Lemli–Opitz syndrome (SLOS, RSH syndrome) is an autosomal recessive disorder from DHCR7 mutations blocking the final step of cholesterol synthesis, causing 7-DHC buildup, low cholesterol, malformations, and intellectual disability.

Smith–Mundt Act

The Smith–Mundt Act is a 1948 statute that allowed the U.S. government to broadcast information internationally while initially prohibiting its release within the United States.

Smith–Waterman algorithm

The Smith–Waterman algorithm is a dynamic-programming method for finding the optimal local alignment of two biological sequences, published by Temple Smith and Michael Waterman in 1981.

Smith+Nephew

Smith+Nephew is a British medical technology company headquartered in Watford, England. Founded in 1856, it makes orthopedic implants, surgical robotics, and advanced wound care products.

Smithereens (1982 film)

Smithereens is Susan Seidelman's 1982 American independent debut drama, starring Susan Berman, Brad Rinn, and punk icon Richard Hell; shot on 16 mm in downtown New York, it was the first American indie to compete for the Palme d'Or at Cannes 1982.

Smithereens (Black Mirror)

Smithereens is Black Mirror season 5 episode 2 (Netflix, June 5, 2019), written by Charlie Brooker and directed by James Hawes. Andrew Scott plays Chris, a rideshare driver who kidnaps a Smithereen intern to reach CEO Billy Bauer (Topher Grace).

Smithfield culture

The Smithfield culture is a Later Stone Age stone tool industry of southern Africa, defined in 1929 near Smithfield, Free State, and characterized by its scrapers.

Smithfield Foods

Smithfield Foods (Nasdaq: SFD), founded 1936 in Smithfield, Virginia, is a major American packaged meats and fresh pork producer, majority owned by WH Group, public since its January 2025 IPO, with brands including Smithfield, Eckrich, and Nathan's Famous.

Smithfield Street Bridge

The Smithfield Street Bridge is a steel lenticular through-truss highway bridge over the Monongahela River in Pittsburgh, designed by Gustav Lindenthal and opened in 1883, the oldest river bridge still standing in Allegheny County.

Smithsonian Agreement

The Smithsonian Agreement was a December 1971 realignment negotiated in Washington by the Group of Ten, devaluing the dollar from $35 to $38 per ounce.

Smithsonian Astrophysical Observatory Star Catalog

The Smithsonian Astrophysical Observatory Star Catalog (SAO Catalog) is a 1966 all-sky catalog of positions and proper motions for 258,997 stars, compiled to help track artificial satellites.

Smithsonian Institution

The Smithsonian Institution, founded by Congress in 1846 from James Smithson's bequest, is the world's largest museum, education, and research complex: 21 museums, 14 research and education centers, the National Zoo, governed by a Board of Regents, about 62% federally funded.

Smithsonian Institution Building

Smithsonian Institution Building, called the Castle, is the Smithsonian's oldest building, completed 1855 in red Seneca sandstone by James Renwick, Jr.; closed since February 2023 for a five-year renovation.

Smithsonite

Smithsonite is a zinc carbonate mineral, ZnCO₃, that forms in oxidized zinc deposits, serves as an ore of zinc, and was named in 1832 for James Smithson.

Smithwick's

Smithwick's (pronounced Smiddicks) is an Irish red ale founded in 1710 by John Smithwick and Richard Cole in Kilkenny, Ireland; brewed there 300 years, taken over by Guinness in 1964-1965, now a Diageo brand.

SMLE

SMLE, pronounced "smile," is an American future bass duo formed in Miami in 2014 by Ruben Cardenas and Lewis Martinee, now based in Los Angeles.

SMN complex and snRNP assembly

SMN complex and snRNP assembly: the survival of motor neuron (SMN) protein complex with Gemins 2–8 and Unrip chaperones assembly of heptameric Sm cores onto snRNAs; its deficiency causes spinal muscular atrophy.

SMN2

SMN2 (survival of motor neuron 2, centromeric) is a human gene on 5q13, a near-copy of SMN1 whose exon 7 splicing defect makes it a modifier of spinal muscular atrophy severity and the target of nusinersen and risdiplam.

Smog

Smog is visible air pollution from smoke, gases, and chemical pollutants, harming health and visibility. The two main types are sulfurous coal-smoke smog and photochemical smog rich in ground-level ozone.

Smoggie Queens

Smoggie Queens: BBC Three sitcom created by and starring Phil Dunning, set in Middlesbrough, following drag queen Dickie's LGBTQ+ chosen family with Mark Benton as Mam; series began November 2024.

Smoke

Smoke is an aerosol released by combustion or thermal decomposition, consisting of gases, vapors, and suspended particles such as soot, with particles mostly under 1 µm across.

Smoke (2018 TV series)

Smoke is a 2018 Hindi-language crime drama web series, an Eros Now original directed by Neel Guha, set in Goa's drug trade and starring Jim Sarbh and Kalki Koechlin.

Smoke (TV series)

Smoke is a 2025 Apple TV+ nine-episode crime drama created by Dennis Lehane, starring Taron Egerton and Jurnee Smollett as investigators hunting two serial arsonists, loosely based on the Firebug podcast and the John Orr arson case.

Smoke + Mirrors

Smoke + Mirrors is Imagine Dragons' second studio album (2015), self-produced with Alex da Kid on KIDinaKORNER/Interscope. Debuted at No. 1 on the Billboard 200, their first US and Canada No. 1; certified 2x Platinum; includes "I Bet My Life".

Smoke detector

A smoke detector, or smoke alarm, is a device that senses airborne smoke and sounds an alarm, giving occupants time to escape a fire. Home alarms use ionization or photoelectric detection.

Smoke Gets in Your Eyes

Smoke Gets in Your Eyes: Kern-Harbach ballad from the 1933 Broadway musical Roberta, lyric built on a Russian proverb; the Platters' 1958 Paris recording hit number one in the US and UK.

Smoke on the Water

Smoke on the Water is Deep Purple's 1972 Machine Head song about the 4 December 1971 Montreux Casino fire during a Frank Zappa concert; its fourths-harmonized G minor riff is the classic beginner guitar riff, and Blackmore rejoined the band to play it in 2026.

Smoke point

The smoke point, also called the burning point, is the temperature at which a cooking oil or fat begins to emit visible smoke as it thermally degrades.

Smoke screen

A smoke screen, or screening smoke, is artificially generated smoke laid over an area or force to block enemy observation or mark targets and landing zones.