All articles starting with T
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Trixie Mattel
Trixie Mattel (Brian Michael Firkus, born 1989, Milwaukee) is an American drag queen, singer-songwriter, and comedian; Drag Race season 7 alum, All Stars 3 winner, Trixie Cosmetics founder, and co-host of The Bald and the Beautiful with Katya.
Trixies
Trixies is the sixteenth studio album by Squeeze, released in 2026. The concept album was written in 1974 by Chris Difford and Glenn Tilbrook, inspired by Damon Runyon's stories.
TRIZ (теория решения изобретательских задач)
TRIZ, the Theory of Inventive Problem Solving, is a systematic method for solving technical problems by eliminating contradictions, developed by Genrich Altshuller in the Soviet Union from 1946.
Trk receptor
Trk receptors (tropomyosin-related kinases) are a family of three receptor tyrosine kinases, TrkA, TrkB, and TrkC, activated by neurotrophins like NGF and BDNF to support neuronal survival.
TRL (Transformer Reinforcement Learning)
TRL (Transformer Reinforcement Learning) is an open-source Hugging Face Python library, released under Apache-2.0, for post-training language models with methods like SFT, DPO, GRPO, and reward modeling.
TrmE-type guanine nucleotide-binding domain
The TrmE-type guanine nucleotide-binding domain is the Ras-like GTPase domain of TrmE, also called MnmE or ThdF, a conserved tRNA-modification GTPase whose potassium-stimulated GTP hydrolysis drives wobble uridine modification.
Trmice CCGT plant
The Trmice CCGT plant is a planned 150 MWe combined-cycle gas-fired cogeneration source at the Teplárna Trmice heating plant in Trmice, Czech Republic, replacing brown-coal boilers by 2030.
tRNA 3′-end maturation
tRNA 3′-end maturation: RNase trimming of precursor 3′ ends and template-independent CCA addition by CCA-adding enzyme (tRNA nucleotidyltransferase), classes I and II, plus CCACCA quality-control tagging.
tRNA A64-2'-O-ribosylphosphate transferase
RIT1 (YMR283C) tRNA A64-2'-O-ribosylphosphate transferase, a yeast cytoplasmic pentosyltransferase modifying initiator tRNA position 64 to discriminate it from elongator tRNAs; distinct from the human Ras-like GTPase gene RIT1.
tRNA identity elements
tRNA identity elements are the nucleotides that tell aminoacyl-tRNA synthetases to attach the correct amino acid, located mainly in the anticodon loop and acceptor stem of the tRNA.
tRNA isoacceptors and isodecoders
tRNA isoacceptors are transfer RNAs carrying the same amino acid but with different anticodons, while isodecoders share an anticodon yet differ in body sequence, with distinct functional and disease consequences.
tRNA methyltransferases
tRNA methyltransferases are enzymes that transfer methyl groups onto transfer RNA, the adaptor RNA delivering amino acids to the ribosome; methylation is the most frequent of about 90 reported tRNA modifications.
tRNA modification epitranscriptomics
tRNA modification epitranscriptomics is the study of chemical modifications on tRNA as dynamic regulatory marks that control translation, with links to stress, neurodevelopment, and cancer.
tRNA pseudouridine synthases
tRNA pseudouridine synthases, or Pus enzymes, are enzymes that convert specific uridines in transfer RNA to pseudouridine; humans encode 13, and mutations in PUS1, PUS3, and PUS7 cause rare diseases.
tRNA-derived small RNA
tRNA-derived small RNAs are short RNA molecules produced by cutting transfer RNAs or their precursors, not by dedicated transcription. They include 14–30 nucleotide tRFs and 28–36 nucleotide tiRNAs, and regulate translation, stress responses, and retrotransposon silencing.
tRNA-guanine transglycosylase
tRNA-guanine transglycosylase (TGT, EC 2.4.2.29, QTRT) exchanges guanine in tRNA for 7-deazaguanines, producing queuosine or archaeosine at the wobble position via a covalent aspartate intermediate.
tRNA-specific 2-thiouridylase MnmA-like
tRNA-specific 2-thiouridylase MnmA-like (InterPro IPR004506): ATP-dependent enzyme family installing sulfur at wobble uridine 34 of tRNAs for Glu, Gln, Lys; bacterial MnmA and mitochondrial Mtu1; [4Fe-4S]-dependent.
tRNA-specific adenosine deaminase 1
TAD1 (ADAT1, scADAT1) is the eukaryotic tRNA-specific adenosine deaminase that deaminates adenosine 37 of tRNA-Ala to inosine, later methylated to m1I37; a homodimeric, non-essential enzyme proposed as the ancestor of ADAR editing proteins.
tRNA-splicing endonuclease subunit Sen15
Sen15 (TSEN15) is the smallest, noncatalytic structural subunit of the eukaryotic tRNA splicing endonuclease heterotetramer, pairing with Sen34; loss-of-function mutations cause pontocerebellar hypoplasia type 2.
tRNA(Ile2) 2-agmatinylcytidine synthetase
tRNA(Ile2) 2-agmatinylcytidine synthetase, also called tRNA(Ile2) agmatidine synthetase (TiaS), is an archaeal enzyme that attaches agmatine to the wobble cytidine of isoleucine tRNA, producing agmatidine, required for accurate AUA decoding.
tRNA/rRNA methyltransferase LasT, C-terminal domain
LasT C-terminal domain (InterPro IPR063618): auxiliary RNA-binding CTD of LasT, an uncharacterized E. coli tRNA/rRNA methyltransferase (b4403, K02533) in the SPOUT TrmJ/LasT family; the Cm32/Um32 activity belongs to TrmJ, not LasT.
tRNAHis guanylyltransferase catalytic domain
tRNAHis guanylyltransferase catalytic domain (Thg1): the RRM-fold polymerase-palm enzyme core that adds G−1 to tRNAHis in the reverse 3′–5′ direction via adenylylation, nucleotidyl transfer, and pyrophosphate removal, using a two-metal-ion mechanism.
Trnava, Slovakia
Trnava (Trnavský kraj) is one of Slovakia's eight self-governing regions, in western Slovakia, with the city of Trnava as its capital and about 566,000 people.
TRNT1-related SIFD
TRNT1-related SIFD is an autosomal recessive disorder caused by variants in the TRNT1 gene, combining sideroblastic anemia, recurrent fevers, B-cell immunodeficiency, and developmental delay, first described in 2013.
Troades
Troades ("The Trojan Women") is a first-century AD Latin tragedy in five acts by Seneca the Younger, reworking Euripides to dramatize the deaths of Astyanax and Polyxena after Troy's fall.
Troas (region)
Troas (Τρωάς), also known as the Troad, is an ancient region in northwestern Asia Minor whose strategic position beside the Hellespont made it prized, and which contains Troy.
Trobriand oral literature
Trobriand oral literature is the spoken myth, story, song, and magic of the Trobriand Islands of Papua New Guinea, transmitted largely in the Kilivila language.
Trocar
A trocar is a surgical device that pierces the body wall to place a cannula, creating an access channel for instruments, optics, and gas, especially in laparoscopy.
Trochaic tetrameter
Trochaic tetrameter is a verse meter built from four trochees, one of the three primary measures of classical Greek and Latin verse, used in drama for hurried or excited dialogue.
Trochidae
Trochidae, the top shells, is the largest family of Trochoidea vetigastropod marine snails, with over 600 species in conical, nacreous-shelled, corneous-operculum grazers and filter feeders worldwide.