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SIM0660

SIM0660 is a preclinical CD79a/CD19/CD3 tri-specific T-cell engager from Simcere Zaiming (2096.HK), licensed globally to Roche on 1 September 2026 for $75 million upfront and up to $1.53 billion total, targeting B-cell-mediated diseases.

SIM0709

SIM0709 is a preclinical, half-life-extended TL1A/IL-23p19 bispecific antibody from Simcere (先聲藥業) for inflammatory bowel disease; Boehringer Ingelheim licensed global rights outside Greater China in January 2026 for up to €1.058 billion.

SIMA 2

SIMA 2 is a generalist embodied agent by Google DeepMind, announced in November 2025, that perceives 3D virtual worlds through video and acts via keyboard and mouse.

Sima Chengzhen

Sima Chengzhen (司马承祯, 647–735) was a Tang-dynasty Daoist master of the Shangqing tradition who served as an adviser on Daoist learning to Wu Zetian and emperors Ruizong and Xuanzong.

Sima clan of Henei

The Sima clan of Henei (河內司馬氏) was a Chinese family from Henan that rose from military service to become a Confucian great family and founded the Jin dynasty.

Sima Cuo's debate on the conquest of Shu

Sima Cuo's debate on the conquest of Shu (司马错论伐蜀) was a 316 BC policy dispute at the Qin court over conquering Shu or attacking Han.

Sima de los Huesos hominins

Sima de los Huesos hominins: Middle Pleistocene humans (~450–430 ka) from the Atapuerca cave "pit of bones" in Spain, at least 29 individuals, the largest Middle Pleistocene hominin assemblage, genetically early Neanderthals with Denisovan-like mtDNA.

Sima Fa

The Sima Fa (司马法) is an ancient Chinese military classic on military rites and warfare, associated with Sima Rangju of Qi and compiled in the Warring States period.

Sima Guang

Sima Guang (司马光, 1019–1086) was a Northern Song historian and statesman who led the compilation of the Zizhi Tongjian, a monumental general history of China.

Sima Guang's Letter to Wang Anshi

Sima Guang's Letter to Wang Anshi (司马光与王介甫书) is a letter of political criticism sent by the Song historian Sima Guang to Wang Anshi, attacking the New Policies of 1069.

sima land-grant system

The sima land-grant system was the ancient Javanese practice of converting rice-field or garden land to tax-exempt status, so royal tax collectors could no longer enter it.

Sima Lang

Sima Lang (司馬朗), courtesy name Boda, was an Eastern Han official who served Cao Cao as Governor of Yanzhou and died in an epidemic during a campaign against Wu.

Sima Qian (司马迁)

Sima Qian (司马迁, c. 145–86 BCE), Western Han court astrologer and imperial secretary under Emperor Wu, compiled the Shiji (Records of the Grand Historian), China's first biographical general history: 130 juan covering about 3,000 years from the Yellow Emperor, in five sections that shaped all later Chinese official historiography.

Sima Qian's castration and completion of the Shiji

Sima Qian's castration and completion of the Shiji refers to the Han historian's punishment in 99 BC and his choice to endure it and finish the Shiji.

Sima Shi

Sima Shi (司马师), courtesy name Ziyuan, was a Wei general and statesman who held effective power over the Wei government from his father Sima Yi's death until his own in 255.

Sima Tan

Sima Tan (司馬談, died 110 BC) was a Western Han Grand Historian under Emperor Wu and the father of Sima Qian, who originated the Shiji.

Sima Xiangru

Sima Xiangru (司马相如) was a Han dynasty fu poet and official from Chengdu, known for the Zixu fu and Shanglin fu and his mission to the southwest.

Sima Xiangru's mission to the Southwest Yi

Sima Xiangru's mission to the Southwest Yi (司马相如通西南夷) was a 130 BC Han diplomatic expedition in which Sima Xiangru accepted the submission of southwestern chiefs.

Sima Xin, Dong Yi and the Surrendered Qin Generals

Sima Xin, Dong Yi and the Surrendered Qin Generals (三秦降将集团) were three surrendered Qin generals whom Xiang Yu made kings over Guanzhong after Qin's fall, known as the Three Qins.

Sima Yi

Sima Yi (司馬懿, Zhongda, 179–251) was a Cao Wei statesman and general who seized power in the Gaoping Tombs coup of 249, executed co-regent Cao Shuang, and founded his family's dominance that led to the Jin dynasty.

Sima Zhao

Sima Zhao (司马昭, 211–265) was a general of the Wei dynasty during the Three Kingdoms period, known for crushing the rebellion at Shouchun and ordering the conquest of Shu Han in 263.

Simaba cedron

Simaba cedron (cedron, cedrón; now Homalolepis cedron), a Simaroubaceae tree from Costa Rica to South America; bitter quassinoid seeds used traditionally against fevers and snakebite.

SimActive Correlator3D

SimActive Correlator3D is photogrammetry software developed by SimActive Inc. of Montreal, Canada, that generates digital surface models, orthomosaics, point clouds, and 3D models from drone, aircraft, and satellite imagery.

Simak ibn Harb

Simak ibn Harb (سماك بن حرب), kunya Abu al-Mughira, was a Kufan hadith scholar of the tabi'un generation who saw about eighty Companions of Muhammad.

Simandou

Simandou is a 110-kilometer mountain range in Guinea holding one of the world's largest untapped high-grade iron ore deposits, with the first shipment in December 2025.

Simão Sabrosa

Simão Sabrosa (Simão Pedro Fonseca Sabrosa, born 1979, Vila Real) is a Portuguese former left winger who played for Sporting, Barcelona, Benfica, Atlético Madrid, Besiktas, Espanyol, and NorthEast United, won 85 Portugal caps, and is now Benfica's technical director.

Simaro Lutumba

Simaro Lutumba (1938–2019) was a Congolese rumba rhythm guitarist and composer nicknamed the Poet, long-serving vice-president of Franco's TPOK Jazz, whom he later led, and composer of 'Mabele' and 'Maya'.

Simarouba

Simarouba (aceituno, bitterwood) is a genus of six dioecious Neotropical trees in Simaroubaceae, type species Simarouba amara, native from Mexico and Florida to South America, introduced to India, and rich in medicinal quassinoids.

Simaroubaceae

Simaroubaceae, the tree-of-heaven or quassia family, is a pantropical Sapindales family of about 20 genera and 110 species of bitter-barked trees and shrubs, sister to Rutaceae and Meliaceae in the SRM clade.

Simat-Ishtaran

Simat-Ishtaran, also written Šāt-Eštar, was a princess of the Third Dynasty of Ur who married the physician and general Šu-Kabta and managed the Garšana estate alone after his death.