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Single-sex education
Single-sex education teaches boys and girls separately in classrooms or schools. Key evidence: the 2014 meta-analysis of 184 studies found trivial controlled effects, while Trinidad and Tobago's 2010 conversions of 20 schools showed causal gains in exam scores, completion, and behavior.
Single-shield tunnel boring machine
A single-shield tunnel boring machine (single-shield TBM) is a hard-rock boring machine that thrusts against the segmental lining it erects, so boring and ring building alternate rather than overlap.
Single-shot
A single-shot firearm is a gun whose mechanism holds no more than one cartridge, requiring manual reload after each shot; it dominated firearms into the 1890s.
Single-shot error correction
Single-shot error correction is a property of quantum error-correcting codes in which a single round of noisy syndrome measurements suffices for reliable correction, replacing repeated rounds.
Single-sideband modulation
Single-sideband modulation (SSB) is an efficient form of amplitude modulation that transmits only one sideband and suppresses the carrier, halving bandwidth; it is the standard voice mode on HF radio.
Single-stage-to-orbit
A single-stage-to-orbit (SSTO) vehicle, also called one stage to orbit, reaches low Earth orbit using a single rocket stage. No Earth-launched SSTO has ever flown.
Single-strand annealing weakened protein 1
Saw1 (single-strand annealing weakened protein 1, SAW1/YAL027W) is a 261-amino-acid Saccharomyces cerevisiae DNA repair scaffold that binds 3'-flap DNA and recruits the Rad1-Rad10 nuclease to recombination intermediates in single-strand annealing.
Single-strand conformation polymorphism
Single-strand conformation polymorphism (SSCP) is an electrophoretic method, first reported in 1989, that detects unknown mutations in PCR-amplified DNA as mobility shifts, which are then sequenced.
Single-subject design
A single-subject design is an experimental method in which one participant is measured repeatedly across baseline and intervention phases, testing whether a treatment changes that person's behavior.
Single-subject research
Single-subject research is a family of experimental designs in which one case is measured repeatedly under alternating baseline and intervention conditions, serving as its own control.
Single-subject rule
The single-subject rule requires US ballot initiatives to address one topic and connected matters. Nineteen states apply it by constitution or statute to curb logrolling and voter confusion.
Single-Tooth Dental Implants
A single-tooth dental implant is a titanium post placed in the jawbone to replace one missing tooth and its root, bonding to bone through osseointegration and carrying a crown.
Single-unit recording
Single-unit recording is an electrophysiology method that measures the action potentials of individual neurons with microelectrodes, in vivo or in vitro, to study neural coding and circuit function.
Single-use bioreactor
Single-use bioreactor: disposable cell culture vessel with a pre-sterilized polymer bag discarded after one batch, used for monoclonal antibodies, vaccines, and cell and gene therapies; pioneered by the 1996 WAVE bioreactor and Hyclone's 2004 stirred tank.
Single-ventricle physiology
Single-ventricle physiology: one functional ventricle pumps to both lungs and body with mixing of blood. Treated by staged Norwood, Glenn, and Fontan palliation; Fontan circulation causes venous hypertension, liver disease, and transplant-dependent failure.
Single-voxel spectroscopy
Single-voxel spectroscopy (SVS) is a magnetic resonance spectroscopy technique that acquires a metabolite spectrum from one small, precisely defined tissue volume, applied mostly to the brain.
Single-walled carbon nanotube conductive additives
Single-walled carbon nanotube conductive additives are SWCNTs added in small mass fractions to lithium-ion battery electrodes, forming conductive networks at far lower loadings than carbon black.
Single-walled carbon nanotubes
Single-walled carbon nanotubes (SWCNTs) are cylindrical nanostructures of single-layer sp²-bonded carbon, typically 1–2 nm in diameter, first synthesized in 1993 by NEC and IBM groups.
Single-wing formation
Single-wing formation, an American football offense devised by Pop Warner in 1906 at Carlisle: direct snap, unbalanced line, wingback, no quarterback; dominant early offense until the T-formation, last NFL use by the Pittsburgh Steelers.
Single, Out
Single, Out is a 2022 Australian comedy-drama web series by Lee Galea, set in Melbourne, following Adam (Will Hutchins) after he comes out as gay; four seasons (2022–2026) streamed on Here TV.
Single's Inferno (솔로지옥)
Single's Inferno (솔로지옥) is Netflix's South Korean reality dating series, debuting December 2021, in which singles stranded on a deserted island escape only by coupling up for luxury-hotel "Paradise" dates; it reached five seasons, first Korean unscripted Global Top 10 entry, and Season 6 confirmation in 2026.
Single's Inferno, season 2 (솔로지옥 2)
Single's Inferno season 2 (솔로지옥 2) is the 2022 second season of Netflix's Korean reality dating show, announced April 12, 2022, premiering December 13 with 10 episodes and 65.08 million Top 10 viewing hours.
Single's Inferno, season 4 (솔로지옥 4)
Single's Inferno season 4 (솔로지옥 4), Netflix Korean dating reality show's fourth season, aired January 14 to February 11, 2025, 12 episodes, four final couples, highest first-week viewership in the franchise.
Single's Inferno, season 5 (솔로지옥 5)
Single's Inferno season 5 (솔로지옥 5), the 2026 fifth season of Netflix's Korean island dating reality show, aired January 20 to February 10, 2026, in 12 episodes with 15 contestants and ended with five final couples.
Singled Out
Singled Out is MTV's dating game show that premiered June 5, 1995, in which a blindfolded picker eliminates 50 contestants to choose a date. Hosted by Chris Hardwick and Jenny McCarthy, later Carmen Electra; rebooted on Quibi in 2020 with Keke Palmer and Joel Kim Booster.
Singlera Genomics (鹍远生物)
Singlera Genomics (鹍远生物) is a cancer early-detection company co-founded in 2014 in San Diego, California, with operations in La Jolla and Shanghai, developing ctDNA methylation screening tests.
Singleron Biotechnologies
Singleron Biotechnologies is a Chinese single-cell sequencing company founded in 2018 that makes instruments, reagents, and software for single-cell RNA sequencing, competing with 10x Genomics on price.
Singles (1992 film)
Singles (1992) is a Cameron Crowe comedy-drama about Seattle twentysomethings in the grunge era, starring Bridget Fonda, Matt Dillon, Campbell Scott, and Kyra Sedgwick, with a landmark grunge soundtrack.
Singles (EP)
Singles is the debut solo EP by American musician Cameron Winter, frontman of Geese, released on October 22, 2024, with the songs "Vines" and "Take It With You".
Singles' Day
Singles' Day, also called Double 11 (双十一), is a Chinese shopping festival held on 11 November that began as a 1990s student joke and became the world's largest retail event.