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Sofie Gråbøl

Sofie Gråbøl (born 1968) is a self-taught Danish actress, famous as Sarah Lund in Forbrydelsen (The Killing) and for Nikolaj & Julie, Fortitude, and multiple Bodil and Robert awards.

Sofie Hagen

Sofie Hagen, Danish stand-up comedian, author, and podcaster; Edinburgh Best Newcomer 2015 for Bubblewrap; books Happy Fat and Will I Ever Have Sex Again?; podcasts Bad People and Help Hole; distinct from designer Sofia Hagen.

Sofie R Salama

Sofie Reda Salama is a genomics and stem-cell biologist, professor at UC Santa Cruz, known for the Shasta genome assembler, the HAR1 and NOTCH2NL genes, and the Treehouse pediatric cancer initiative.

Sofie Surgical Robot

Sofie (Surgeon's Operating Force-feedback Interface Eindhoven) is an experimental surgical robot for minimally invasive surgery developed at Eindhoven University of Technology, offering force feedback and a compact, table-mounted slave robot.

Sofina

Sofina is a Brussels-listed, family-controlled investment holding company founded in Brussels in 1898, holding long-term minority stakes in companies and private-equity funds, with a net asset value of EUR 10.8 billion at the end of 2025.

Sofinnova Partners

Sofinnova Partners is a Paris-based European venture capital firm specializing in life sciences, founded in 1972, which has backed over 500 companies and manages more than €4 billion in assets.

Sofinnova Venture Partners

Sofinnova Venture Partners is the life-sciences venture capital fund family managed by Sofinnova Investments, Inc., a healthcare adviser on Sand Hill Road in Menlo Park, California.

Sofiya Ozerkova

Sofiya Ozerkova, born in 1912, was a Soviet military engineer who led the Night Witches regiment's engineering service and survived a 1942 death sentence, finishing the war a Guards captain.

Sofiya Pozdnyakova

Sofiya Pozdnyakova (София Позднякова, born 1997, Novosibirsk) is a Russian sabre fencer, daughter of Stanislav Pozdnyakov, who won individual and team sabre gold at Tokyo 2020 for ROC.

Sofoklis Venizelos

Sofoklis Venizelos (Σοφοκλής Βενιζέλος) was a Greek politician, son of Eleftherios Venizelos, who served several terms as Prime Minister of Greece in the 1940s and 1950s.

Sofonisba Anguissola

Sofonisba Anguissola (c. 1532–1625), Cremona-born Renaissance portrait painter; trained under Bernardino Campi and Gatti, admired by Michelangelo and Vasari; lady-in-waiting and painting teacher to Elisabeth of Valois at Philip II's Spanish court; died Palermo 1625.

Sofosbuvir

Sofosbuvir (Sovaldi), Gilead's nucleotide analog NS5B polymerase inhibitor approved by the FDA in December 2013, treats chronic hepatitis C; first all-oral HCV regimen, 400 mg once daily, now available as low-cost generics.

Sofpironium

Sofpironium (sofpironium bromide, BBI-4000; brands Sofdra, ECCLOCK/エクロック) is a topical retrometabolic anticholinergic gel for primary axillary hyperhidrosis, approved in Japan 2020 (5%) and by FDA June 2024 (12.45%).

SOFR

SOFR, the Secured Overnight Financing Rate, is a benchmark rate measuring the cost of overnight borrowing against U.S. Treasury securities, published daily by the New York Fed.

Sofrito

Sofrito is an aromatic flavor base of vegetables and herbs in fat, central to Spanish, Caribbean, and Latin American cooking; Puerto Rican recaíto is its raw green, culantro-based, tomato-free variant.

Sofronio Vasquez

Sofronio Vasquez III (born 1992, Ozamiz, Philippines) is a Filipino pop-R&B singer based in Utica, New York, and winner of The Voice USA Season 26 in December 2024, the first Filipino and first Asian champion, coached by Michael Bublé.

Soft & Quiet

Soft & Quiet is a 2022 American real-time thriller, the feature debut of writer-director Beth de Araújo, about a white supremacist women's group whose store altercation escalates into a home invasion. Shot as a one-take film, released by Momentum Pictures with Blumhouse producing.

Soft Actor-Critic

Soft Actor-Critic (SAC) is an off-policy, maximum-entropy actor-critic deep reinforcement learning algorithm for continuous control, introduced by Haarnoja, Zhou, Abbeel, and Levine at ICML 2018.

Soft agar assay

The soft agar assay is a cell biology method that grows cells suspended in semi-solid agar to test anchorage-independent growth, serving as an in vitro proxy for tumorigenic potential.

Soft and hard cleft palate

Soft and hard cleft palate (ORPHA:664372, ICD-10 Q35.5) is a congenital cleft extending through both the hard and soft palate, multifactorial in origin, causing hypernasal speech, malocclusion, and maxillary hypoplasia, repaired by palatoplasty.

Soft bigotry of low expectations

Political phrase coined by Michael Gerson for George W. Bush's education agenda, describing lowered expectations for disadvantaged children; signature line of No Child Left Behind, later adopted and contested across politics.

Soft budget constraint

A soft budget constraint is a financial condition where an organization overspends expecting the state to cover its losses, a concept introduced by János Kornai in 1979.

Soft carbon

Soft carbon, or graphitizable carbon, is a disordered carbon that converts to graphite when heated above 2500 °C, used as an anode in sodium-ion batteries and as a graphite precursor.

Soft Cell

Soft Cell: English synth-pop duo of Marc Almond and Dave Ball, who met at Leeds Polytechnic in 1977. Known for the 1981 UK Number 1 'Tainted Love', Non-Stop Erotic Cabaret, the 1984 split, 2000s reunion, and final album Danceteria (2026).

Soft clustering

Soft clustering is a family of clustering algorithms that assign each data point a degree of membership in every cluster instead of a single hard label.

Soft corn

Soft corn (heloma molle, interdigital or kissing corn) is a painful, macerated hyperkeratotic lesion between adjacent toes, usually the fourth and fifth, caused by friction between bony prominences and moisture, treated with footwear changes, padding, or surgery.

Soft dipole mode

The soft dipole mode is a low-energy electric dipole excitation in halo nuclei, where weakly bound halo neutrons oscillate against the core, producing enhanced strength near the separation threshold.

Soft dollars

Soft dollars are client brokerage commissions that investment managers use to pay for research and related services instead of paying in cash from their own funds.

Soft drink

Soft drink: nonalcoholic, usually sweetened, often carbonated beverage (soda, pop). Includes sugary and diet sodas like Coca-Cola (1886) and Dr Pepper (1885); linked to obesity, diabetes, and taxed via levies like the UK SDIL.

Soft error

A soft error is a transient, nondestructive circuit fault in which a high-energy particle strike, from cosmic-ray neutrons or alpha particles, changes a memory cell state without damaging hardware.