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Sterol 14-demethylase
Sterol 14-demethylase (CYP51, EC 1.14.14.154) is a cytochrome P450 removing the 14α-methyl group of sterols in all kingdoms of life; it is the target of azole antifungals, agricultural fungicides, and antitrypanosomal drug development.
Sterol 22-desaturase
Sterol 22-desaturase (C22DES, ERG5/CYP61 in fungi, CYP710 in plants) is a cytochrome P450 enzyme adding a C22(23) double bond to sterols, making ergosterol and stigmasterol; absent in humans, azole-sensitive, an antifungal target.
Sterol C-14 reductase (14-sterol reductase step)
Sterol C-14 reductase (EC 1.3.1.70, ERG24/TM7SF2/LBR/FK) is an NADPH-dependent membrane enzyme reducing the C14(15) double bond in sterol biosynthesis; LBR mutations cause Greenberg dysplasia and Pelger-Huët anomaly.
Sterol C-24 methyltransferase
Sterol C-24 methyltransferase (SMT) is a membrane-bound enzyme that adds a methyl group to sterol side chains in fungi and plants, making ergosterol and phytosterols.
Sterol C-24 reductase in plants (FACKEL/DWARF1)
Sterol C-24 reductase in plants, encoded in Arabidopsis by the DWARF1 (DIMINUTO) gene, is an FAD-containing enzyme that reduces the C-24 double bond of phytosterol intermediates, producing campesterol and sitosterol.
Sterol C-4 demethylation complex
The sterol C-4 demethylation complex is a three-enzyme assembly of the endoplasmic reticulum that removes the methyl groups at carbon 4 of sterols during ergosterol and cholesterol biosynthesis.
Sterol esterase
Sterol esterase (EC 3.1.1.13, CAS 9026-00-0) hydrolyzes sterol esters; a Trichoderma reesei-produced preparation from Melanocarpus albomyces is FDA GRAS (GRN 981) for baked goods at up to 10 mg TOS/kg flour.
Sterol regulatory element-binding protein
SREBPs (SREBP-1a, SREBP-1c, SREBP-2) are membrane-bound bHLH-Zip transcription factors regulating cholesterol, fatty acid, and triglyceride synthesis, activated by SCAP-mediated Golgi cleavage and retained by Insig when sterols are high.
Stertor
Stertor is a low-pitched, snoring-like breathing sound from soft-tissue vibration above the larynx (nose, nasopharynx, oropharynx), ICD-11 MD11.80; distinct from high-pitched stridor, seen in sleep, coma, congestion, and adenotonsillar hypertrophy.
Stesichorus
Stesichorus (Στησίχορος), traditionally named Teisias, was a Greek lyric poet from Himera in Sicily, active c. 600–550 BC, who retold Trojan and Heraclean myths on an epic scale.
Stethoscope
Stethoscope: acoustic or electronic instrument for auscultation of heart, lung, bowel, and vessel sounds. Invented by René Laënnec in 1816; binaural design 1851–1852; now includes digital and FDA-cleared AI-assisted models such as eMurmur Heart AI.
Stetson
Stetson, the American hat brand founded by John B. Stetson in Philadelphia in 1865, created the Boss of the Plains, the original cowboy hat. Now Hatco-owned and made in Garland, Texas alongside Resistol, with proprietary X ratings and the Open Road as its signature model.
Stetson Bennett
Stetson Bennett IV, Georgia Bulldogs quarterback, two-time CFP national champion (2021, 2022), 2022 Heisman finalist and Burlsworth Trophy winner, walk-on turned Los Angeles Rams fourth-round pick (128th, 2023 NFL Draft).
Stetson University
Stetson University: private university in DeLand, Florida, founded 1883 as DeLand Academy, renamed for hat maker John B. Stetson; law school in Gulfport ranked No. 1 in trial advocacy.
Stetter reaction
The Stetter reaction is a 1,4-conjugate addition of an aldehyde to a Michael acceptor forming 1,4-dicarbonyl compounds, catalyzed by cyanide, thiazolium salts, or N-heterocyclic carbenes, and reported in 1973.
Steuart Walton
Steuart Walton (born 1981) is an American businessman and Walmart director who in 2016 became the first third-generation Walton on the board, and co-founded Runway Group.
Steubenville High School rape case
The Steubenville High School rape case: 2012 Ohio case in which football players Trent Mays and Ma'lik Richmond were found delinquent for raping an intoxicated 16-year-old, documented on social media, prompting an Anonymous campaign and a grand jury.
Steubenville, Ohio
Steubenville, Ohio: Jefferson County seat on the Ohio River, founded 1797 and named for Fort Steuben; former steel town of 17,922 (2025 est.), home to Franciscan University.
Stevan Jovetić
Stevan Jovetić (Стеван Јоветић), born 1989 in Titograd/Podgorica, Montenegrin second striker; Partizan and Fiorentina product, Manchester City, Inter, Monaco, Hertha, Olympiacos; Montenegro's all-time top scorer, 91 caps, 37 goals.
Stevan Nadj-Perge
Stevan Nadj-Perge is a Serbian-born experimental condensed-matter physicist, Professor of Applied Physics and Materials Science at Caltech since 2023, known for Majorana and moiré superconductivity work.
Stevan R. Hubbard
Stevan R. Hubbard is a structural biologist and adjunct professor at NYU Grossman School of Medicine, known for determining the crystal structure of the insulin receptor tyrosine kinase domain.
Stevan Ridley
Stevan Ridley, former LSU and New England Patriots running back, 2011 third-round pick; 1,263 rushing yards and 12 touchdowns in 2012, career 3,102 yards, ended by 2014 ACL and MCL tear.
Stevan Sekulic
Stevan Sekulic (Стеван Секулић) is a Serbian singer from Novi Sad who debuted in 2019 with "7 noći" and is known for singles like "Haljina" and "Takva kosa crna".
Steve
Steve is a masculine given name that peaked in the United States in 1959, and it is most famous for being used by tech founders Steve Jobs and Steve Wozniak.
Steve (2025 film)
Steve (2025) is a Netflix drama directed by Tim Mielants, adapted by Max Porter from his novella Shy, starring Cillian Murphy as a 1990s reform-school headteacher; premiered at TIFF, released September 19, 2025.
Steve (Minecraft)
Steve is the default player character (avatar) of Minecraft, a blocky human skin present since 2009, named "Steve?" as a joke by creator Markus "Notch" Persson; joined by Alex in 2015 and played by Jack Black in A Minecraft Movie.
Steve A. Kay
Steve A. Kay, also published as Steve Kay, is a chronobiologist at the University of Southern California who studies circadian clocks in plants, mice, and human cells.
Steve Albini
Steve Albini (1962-2024), American recording engineer and musician, frontman of Big Black and Shellac, engineer of Nirvana's In Utero and Pixies' Surfer Rosa, founder of Chicago's Electrical Audio studio, known for refusing royalties and the credit 'Recorded by Steve Albini'.
Steve Albini discography
Steve Albini discography: the recorded output of the American engineer (1962–2024) and his bands Big Black, Rapeman, and Shellac, plus credits such as Surfer Rosa, Rid of Me, and In Utero, all recorded at flat fee.
Steve Albrecht
Steve Albrecht is a physicist who heads the Perovskite Tandem Solar Cells department at Helmholtz-Zentrum Berlin and is a professor at TU Berlin, working on perovskite/silicon tandem solar cells.