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ACTIBATE trial

ACTIBATE (Activating Brown Adipose Tissue Through Exercise), NCT02365129, a University of Granada randomized controlled trial in 145 young sedentary adults testing 24 weeks of moderate or vigorous endurance-plus-resistance training; it found no change in brown adipose tissue volume or activity but improved fitness and reduced adiposity.

Sep 29, 2026

Actigraphy

Actigraphy is a sleep medicine method using a wrist-worn accelerometer to record movement over 7 to 14 days and estimate total sleep time and sleep efficiency.

Actin

Actin: conserved eukaryotic cytoskeletal protein; G-actin monomers polymerize into F-actin filaments with ATP-driven treadmilling. Six mammalian isoforms (ACTA1, ACTA2, ACTB, ACTC1, ACTG1, ACTG2) have distinct tissue roles; mutations cause myopathies.

Actin cytoskeleton-regulatory complex protein End3

End3p (END3, UniProt P39013) is a 40-kDa, 349-amino-acid Saccharomyces cerevisiae protein of the PAN1 complex, required for endocytic internalization, actin cytoskeleton organization, Sla1 recruitment, and chitin distribution.

Actin patch protein 1

Actin patch protein 1 (App1p, APP1/YNL094W) is a Saccharomyces cerevisiae phosphatidate phosphatase (EC 3.1.3.4) at cortical actin patches, converting phosphatidate to diacylglycerol for endocytosis; distinct from APD1.

Actin-rearrangement-inducing factor

Actin-rearrangement-inducing factor 1 (Arif-1, ARIF-1) is an early AcMNPV baculovirus protein, encoded by orf20/21, that remodels host F-actin, induces invadosomes, and aids systemic infection in alphabaculoviruses.

Acting

Acting is the intentional, theatrical art of performing a role with voice and body. Key frameworks include Stanislavski's system, the American Method (Strasberg), Meisner, Adler, and Brecht's distancing effect.

Acting (law)

Acting (law): doing acts on behalf of a principal under agency law. Covers express, implied, and apparent (ostensible) authority, ratification, attorney-in-fact powers, vicarious tort liability, and rules on who may represent parties in court.

Acting coach

Acting coach: a specialist giving one-on-one preparation for auditions, self-tapes, callbacks, and roles, distinct from acting classes; draws on Stanislavski-derived techniques (Meisner, Strasberg, Adler), with published LA rates from $85 to $300 per hour as of July 2026.

Acting President of the United States

Acting President of the United States: the Vice President or a statutory successor who discharges presidential powers and duties during disability under 25th Amendment Sections 3 and 4; used by Reagan, Bush, Biden; Section 4 never invoked.

Actinia (sea anemone)

Actinia is a genus of actiniid sea anemones (Linnaeus, 1767) whose type species is the beadlet anemone Actinia equina; most historical Actinia names are reassigned, and A. equina is a cryptic species complex.

Actiniarian classification

Actiniarian classification: taxonomy of sea anemones (order Actiniaria, ~1,200 species, Hexacorallia). Carlgren's 1949 system was replaced after molecular phylogenetics; current suborders Anenthemonae, Enthemonae, and Helenmonae.

Actinic elastosis

Actinic elastosis (solar elastosis, elastosis senilis, ICD-10 L57.4) is yellow, thickened, wrinkled sun-damaged skin from abnormal dermal elastin accumulation due to cumulative UV exposure, managed by sun protection and smoking cessation.

Actinic keratosis

Actinic keratosis (solar keratosis) is a UV-induced precancerous, scaly skin lesion on sun-exposed skin, classified by many as SCC in situ, with 0.025-16% yearly progression risk to squamous cell carcinoma and treatments including cryosurgery, 5-fluorouracil, imiquimod, and photodynamic therapy.

Actinic lentigo

Actinic lentigo (solar lentigo, lentigo senilis, liver spots): benign hyperpigmented macule on sun-exposed skin of elderly people, appearing after the fifth decade, not fading in winter, treated mainly with laser therapy.

Actinic lichen planus

Actinic lichen planus (lichen planus actinicus, lichen planus subtropicus) is a rare photosensitive variant of lichen planus causing annular or hyperpigmented plaques on sun-exposed skin, mainly in young adults with darker skin.

Oct 20, 2026

Actinic prurigo

Actinic prurigo, also called Hutchinson's summer prurigo or hereditary polymorphous light eruption of American Indians, is a rare chronic photodermatosis causing intensely itchy papules on sun-exposed skin, cheilitis, conjunctivitis, and strong HLA-DRB1*0407 association.

Actinidain

Actinidain (actinidin, EC 3.4.22.14, Act d 1) is the abundant cysteine protease of kiwifruit, 50–60% of soluble protein, used for meat tenderization, milk clotting, and milk protein hydrolysis, milder on meat surfaces than papain.

Actinide

The actinide, or actinoid, series comprises 15 radioactive metallic elements with atomic numbers 89 to 103, from actinium through lawrencium, in which the 5f shell is filled.

Actinide boost

The actinide boost is an anomaly in some r-process-enhanced metal-poor stars, where thorium and uranium appear well above predicted levels relative to stable elements like europium.

Actinide chemistry

Actinide chemistry is the branch of inorganic chemistry that studies the actinide series, the 14 radioactive elements from thorium to lawrencium, and their distinctive covalent bonding.

Actinide multiple bonding

Actinide multiple bonding is the formation of double, triple, or higher-order covalent bonds between actinide elements and ligands, engaging the 5f and 6d orbitals in covalency.

Actinide single-molecule magnets

Actinide single-molecule magnets are coordination complexes of actinides like uranium and neptunium that retain magnetization at low temperature, studied for data storage and quantum computing.

Actinidia

Actinidia (kiwifruit genus) is a genus of Asian climbing plants in Actinidiaceae, established by Lindley in 1836, with about 56 accepted species native from the Himalaya to the Russian Far East and Malesia, including the kiwifruit species A. chinensis and A. deliciosa.