951 articles
Second Doctor
The Second Doctor is Patrick Troughton's incarnation of Doctor Who's Doctor, 1966-1969, first seen in The Tenth Planet, forced to regenerate in The War Games, and returning in The Two Doctors (1985).
Seeley Booth
Seeley Joseph Booth is the FBI Special Agent and Jeffersonian liaison in Fox's Bones (2005-2017), played by David Boreanaz; a former 75th Ranger sniper from Philadelphia who partners with and later marries Temperance Brennan.
Senua's Saga: Hellblade II
Senua's Saga: Hellblade II is Ninja Theory's 2024 Unreal Engine 5 narrative action-adventure sequel set in 10th-century Iceland, released May 21, 2024 on Xbox Series X|S, PC, and Game Pass at $49.99, later Enhanced on PS5 August 12, 2025.
Seong Gi-hun (성기훈)
Seong Gi-hun (성기훈) is the main protagonist of the South Korean survival drama Squid Game. He is played by Lee Jung-jae and wins the 45.6 billion won prize.
Serena (セレナ) (Pokémon)
Serena (セレナ) is a Pokémon character: the female player character and gender-based rival of Pokémon X and Y, and the anime Pokémon Performer and Ash companion aiming to become Kalos Queen.
Serena van der Woodsen
Serena van der Woodsen is the fictional Gossip Girl socialite created by Cecily von Ziegesar and played by Blake Lively on the CW's 2007-2012 series, Blair Waldorf's best friend and rival.
Seth Cohen
Seth Cohen, full name Seth Ezekiel Cohen, is the fictional nerd-heartthrob character played by Adam Brody on Fox's teen drama The O.C. (2003–2007), co-creator of Chrismukkah, credited with popularizing indie music and comics, distinct from the mathematician Seth Sullivant.
Seth Milchick
Seth Milchick, also called Mr. Milchick, is the un-severed Lumon Industries middle manager in Severance, played by Tramell Tillman; he manages the severed floor and won Tillman a historic Emmy.
Seven of Nine
Seven of Nine, Tertiary Adjunct of Unimatrix Zero One, born Annika Hansen, is a Star Trek ex-Borg character played by Jeri Ryan in Voyager (1997-2001) and Picard, where she becomes Enterprise captain.
Seventh Doctor
Seventh Doctor, Doctor Who incarnation played by Sylvester McCoy (1987–1989, 1996 movie), first appearing in Time and the Rani; companion Ace; evolved from comic clown to devious Cartmel-era strategist; regenerated into the Eighth Doctor in the 1996 TV movie.
Shane McCutcheon
Shane McCutcheon is the androgynous hairstylist heartthrob of Showtime's The L Word and its sequel The L Word: Generation Q, played by Katherine Moennig; known for serial romances, a salon empire, and the 2019 revival.
Shane Walsh (The Walking Dead)
Shane Walsh is a The Walking Dead TV character played by Jon Bernthal, Rick Grimes's police partner, Season 1 deuteragonist and Season 2 antagonist, killed by Rick after an affair with Lori; his comic counterpart dies in issue 6.
Shannon Rutherford
Shannon Rutherford, played by Maggie Grace, is a fictional Lost character, spoiled stepsister of Boone Carlyle, an Oceanic 815 survivor who translates Rousseau's French signal, romances Sayid, and is shot by Ana Lucia in 'Abandoned' (2005).
Shining Armor
Shining Armor is a male unicorn in My Little Pony: Friendship is Magic, Twilight Sparkle's older brother, Princess Cadance's husband, former Canterlot Royal Guard captain and co-ruler of the Crystal Empire, introduced in "A Canterlot Wedding".
Shiv Roy
Siobhan "Shiv" Roy, played by Sarah Snook, is Logan Roy's only daughter in HBO's Succession (2018–2023); her finale vote sells Waystar Royco to GoJo, making her husband Tom CEO.
Silence (Doctor Who)
The Silence are fictional memory-erasing alien villains created by Steven Moffat for Doctor Who series 6 (2011), designed by Neill Gorton from Edvard Munch's The Scream and the Men in Black; also the religious Order of the Silence tied to the 'Silence will fall' arc.
Simpson family
The Simpson family is the fictional household of Homer, Marge, Bart, Lisa, and Maggie in Springfield, created by Matt Groening for The Simpsons, an animated sitcom satirizing the American nuclear family.
Sith
The Sith are the ancient dark-side order of Force-wielders in Star Wars, enemies of the Jedi, known for red lightsabers, Darth Bane's Rule of Two, and Darth Sidious' galactic conquest.
Sixth Doctor
The Sixth Doctor is the sixth incarnation of Doctor Who's title character, played by Colin Baker, debuting in The Twin Dilemma (1984) and featuring in The Trial of a Time Lord. Known for a patchwork costume, the Valeyard storyline, and a rehabilitated reputation via Big Finish audio.
Skyler White
Skyler White (Skyler Lambert) is Walter White's wife in Breaking Bad (AMC, 2008–2013), played by Anna Gunn; pregnant homemaker turned money-laundering accomplice, Emmy-winning role, and the center of a famous audience-hate and later critical-reassessment debate.
Slayer (Buffy the Vampire Slayer)
Slayer (Buffy the Vampire Slayer): the chosen one-girl-per-generation vampire hunter of the Buffyverse, including the Watchers' Council, the First Slayer's origin, the Slayer line, and the finale's sharing of power.
Snezhnaya (Genshin Impact)
Snezhnaya (Снежная, 至冬) is the seventh, Cryo-aligned nation of Teyvat in Genshin Impact, ruled by the Tsaritsa Anastasya Feodorovna Snezhnaya, home of the Fatui and the Eleven Harbingers, playable from Version 7.0.
Sokka
Sokka is a main character in the animated series Avatar: The Last Airbender, a Southern Water Tribe warrior and Katara's brother who serves as Team Avatar's non-bending strategist.
Sontaran
Sontaran: fictional clone-warrior alien race from Doctor Who, from the planet Sontar; first appeared 1973 in The Time Warrior; locked in a millennia-long war with the Rutans; weak spot is the probic vent; Strax is the only recurring member.
Sophia Peletier
Sophia Peletier, Carol and Ed's daughter in The Walking Dead (comic and AMC TV series). TV Sophia dies as a walker in Season 2's barn reveal; comic Sophia survives, marries Carl, and has daughter Andrea.
Soundwave (Transformers)
Soundwave is the Decepticon Communications Officer in Transformers, a microcassette-recorder robot voiced by Frank Welker since 1984, who deploys cassette minions such as Laserbeak and Ravage and serves as Megatron's loyal intelligence chief.
Space Ghost
Space Ghost is a Hanna-Barbera superhero created by Alex Toth, debuting on CBS in 1966, best known for his power bands and for being recast in 1994 as the host of Cartoon Network's surreal talk show Space Ghost: Coast to Coast.
Species 8472
Species 8472, later named the Undine, is a fictional telepathic Star Trek species from fluidic space, immune to Borg assimilation, nearly destroying the Collective before Voyager's nanoprobe warheads forced their retreat.
Speedster (fiction)
Speedster (fiction): characters whose defining trait is super speed, from DC's Flash (Jay Garrick, 1940) to Marvel's Quicksilver; marked by secondary powers, the Speed Force, and physical limits.
Spencer Hastings
Spencer Jill Hastings is the overachieving protagonist of Pretty Little Liars, played by Troian Bellisario; daughter of Veronica and Peter Hastings, birth daughter of Mary Drake, twin of Alex Drake, and Toby Cavanaugh's endgame.