3 articles
ABCD1
ABCD1 (ATP-binding cassette subfamily D member 1), also called the ALD gene, at Xq28 encodes ALDP, a peroxisomal half-transporter importing VLCFA-CoA for beta-oxidation; mutations cause X-linked adrenoleukodystrophy.
ABCE1
ABCE1 (RNase L inhibitor, RLI1, HP68) is an essential soluble ABC ATPase with two [4Fe-4S] clusters that recycles ribosomes in eukaryotes and archaea, splitting them with eRF1 or Pelota using an ATP-driven conformational switch.
ABCF protein
ABCF proteins are soluble ATP-binding cassette family ATPases lacking transmembrane domains, with two NBDs joined by a PtIM linker. They act as ribosomal translation factors; bacterial ARE ABCFs confer antibiotic resistance by ribosomal target protection.