5 articles
Concentrative nucleoside transporter, metazoan/bacterial
A concentrative nucleoside transporter (CNT) is a membrane transport protein that imports nucleosides into cells, using sodium in metazoans and protons or sodium in bacteria.
Cytosine permease
Cytosine permease (CodB, codB gene, UniProt P0AA82) is the E. coli inner-membrane NCS1 transporter that imports cytosine in a sodium-dependent way, part of the codBA operon with cytosine deaminase.
Equilibrative nucleoside transporter
Equilibrative nucleoside transporters (ENTs, SLC29 family; ENT1-ENT4) are sodium-independent, bidirectional membrane transporters of nucleosides, nucleobases, and nucleoside-analog drugs, key pharmaceutical targets modulating over 30 approved drugs.
Nucleobase cation symporter-1, NCS1
Nucleobase cation symporter-1 (NCS1) family: secondary active membrane transporters in bacteria, archaea, fungi, and plants that import nucleobases, hydantoins, and vitamins via proton or sodium symport; distinct from neuronal calcium sensor NCS1.
Nucleoside transporter
Nucleoside transporters (CNTs/SLC28, ENTs/SLC29) move nucleosides and analog drugs across membranes; CNTs are sodium-coupled concentrative symporters, ENTs sodium-independent equilibrative uniporters, key to gemcitabine, ribavirin, and cladribine pharmacology.