2 articles
Decoy death receptors
Decoy death receptors are TNF receptor superfamily members, such as DcR1 and DcR2, that bind death ligands like TRAIL but cannot trigger apoptosis because they lack a functional death domain.
Osteoprotegerin
Osteoprotegerin (OPG, TNFRSF11B, OCIF) is a secreted TNF receptor superfamily decoy receptor that binds RANKL to block osteoclast formation, protecting bone mass; mutations cause juvenile Paget's disease.