5 articles
Mitochondrial import receptor subunit Tom22
Tom22 (TOM22_YEAST, P49334), the central receptor subunit of the mitochondrial TOM import complex; binds preproteins on both membrane sides, stabilizes the Tom40 pore dimer, and is conserved across all eukaryotes.
Mitochondrial import receptor subunit Tom6
Tom6 (TOMM6, TOM6) is a small single-pass α-helical subunit of the mitochondrial TOM protein-import complex that stabilizes Tom40, promotes tetramerization, and is conserved in opisthokonts and plants.
Mitochondrial outer membrane translocase complex, subunit Tom5
Tom5, a ~50-amino-acid single-pass subunit of the mitochondrial TOM complex, links import receptors to the Tom40 general import pore via an acid chain and stabilizes the complex; nonessential in yeast, structurally resolved in the human TOM dimer.
Mitochondrial outer membrane translocase complex, subunit Tom70
Tom70, historically named MAS70 in yeast, is a receptor subunit of the TOM complex that recognizes hydrophobic mitochondrial precursor proteins, especially inner membrane metabolite carriers.
Translocase of the outer membrane
Translocase of the outer membrane (TOM complex, TOMCC): the mitochondrial outer membrane protein entry gate, built on the Tom40 β-barrel with receptors Tom70, Tom22, Tom20; imports most nucleus-encoded mitochondrial precursors.