2 articles
Dofetilide
Dofetilide, sold as Tikosyn, is a Class III antiarrhythmic drug that blocks a cardiac potassium current to convert atrial fibrillation and must be started in hospital under monitoring.
Hereditary atrial fibrillation
Hereditary atrial fibrillation, also called familial or early-onset AF, is atrial fibrillation driven by inherited variants, from monogenic KCNQ1, SCN5A, TTN, and LMNA mutations to polygenic risk, with 2023 guideline Class IIb genetic testing for onset before age 45.