30 articles
Acoustic reflex
Acoustic reflex: involuntary stapedius (and tensor tympani) contraction to loud sound, measured as thresholds of 85-100 dB SPL at 500-2000 Hz; used to diagnose middle-ear, cochlear, and retrocochlear disorders.
Auditory cortex
The auditory cortex is the region of the temporal lobe that receives and processes sound information from the ears, with primary area A1 on Heschl's gyrus.
Auditory scene analysis
Auditory scene analysis is the framework describing how listeners group a sound mixture into separate auditory streams, established in Albert Bregman's 1990 monograph and the basis of computational sound-separation systems.
Basilar membrane
Basilar membrane: elastic membrane dividing the cochlea's scala media and scala tympani, carrying the tonotopic traveling wave discovered by von Békésy (Nobel 1961), later shown to be nonlinear and amplified by outer hair cells.
Binaural hearing
Binaural hearing is the brain's use of input from both ears to locate sounds in space, based on differences in arrival time and intensity between the ears.
Bushy cell
Bushy cell: a principal neuron of the ventral cochlear nucleus with short bushy dendrites, two types (spherical, globular), endbulb of Held inputs, and projections for binaural sound localization.
Cochlear amplifier
Cochlear amplifier: active process in the mammalian cochlea, also called cochlear amplification, where outer hair cells and prestin enhance basilar membrane vibration, giving hearing sensitivity, sharp tuning, and otoacoustic emissions.
Cochlear nerve
Cochlear nerve: auditory division of cranial nerve VIII, carrying signals from spiral ganglion neurons to the brainstem cochlear nuclei; aplasia or hypoplasia predicts poor cochlear implant outcomes, with auditory brainstem implants as the alternative.
Cochlear nucleus
Cochlear nucleus: first brainstem relay of the auditory pathway (dorsal, anteroventral, posteroventral divisions), where auditory nerve fibers split into ventral sound-localizing and dorsal pattern-recognition streams; target of auditory brainstem implants and linked to tinnitus.
Comparative auditory physiology
Comparative auditory physiology studies how vertebrate ears detect and discriminate sound across species, using differences among fish, amphibians, reptiles, birds, and mammals to interpret human hearing.
Dorsal cochlear nucleus
Dorsal cochlear nucleus (DCN), part of the cochlear nucleus with the ventral cochlear nucleus; a laminar, cerebellum-like auditory brainstem nucleus processing spectral cues for sound localization and implicated in tinnitus and hyperacusis.
Endocochlear potential and cochlear homeostasis
Endocochlear potential (EP), the ~+80 mV positive potential of cochlear endolymph generated by the stria vascularis via Kir4.1 channels, drives hair-cell transduction; its maintenance through potassium recycling defines cochlear homeostasis.
Head-related transfer function
Head-related transfer function (HRTF): direction-dependent acoustic filter of sound by a listener's head, pinnae, and torso, measured at the ear canal entrance; listener-specific like a fingerprint, basis of binaural VR audio, carrying ITD, ILD, and spectral localization cues.
Hearing
Hearing: the sense converting sound waves into electrical signals via the ear canal, eardrum, malleus-incus-stapes chain, and cochlear hair cells, with tonotopic coding carried by the auditory nerve to the brain; distinct from balance, the inner ear's other function.
Hearing range
Hearing range, the span of frequencies and intensities an ear detects; humans hear about 20 Hz to 20 kHz (adults often 15–17 kHz upper limit), best sensitivity 2000–5000 Hz, declining with age.
Human echolocation
Human echolocation: using reflected sound, especially self-generated mouth clicks, to sense silent objects. Practiced by some blind people and trainable by sighted people; term coined 1944; 10-week training studies show broad learning.
Inferior colliculus
The inferior colliculus (IC) is a paired midbrain structure serving as the main relay for auditory information traveling from the inner ear to the auditory cortex, supporting sound localization.
Interaural time difference
Interaural time difference (ITD): the arrival-time difference of a sound at the two ears, the dominant cue for horizontal sound localization at low frequencies, encoded by coincidence-detecting MSO neurons, with human sensitivity near 10 microseconds and a maximum near 763 microseconds.
Olivocochlear system
Olivocochlear system: brainstem-to-cochlea efferent pathway from the superior olivary complex, divided into medial (MOC, outer hair cells, cholinergic gain reduction) and lateral (LOC) divisions, studied via otoacoustic emissions for protection and speech-in-noise roles.
Organ of Corti
Organ of Corti: the mammalian cochlea's hearing sensory epithelium, on the basilar membrane under the tectorial membrane; one inner and three outer hair-cell rows, tunnel of Corti, described by Corti in 1851.
Pitch and loudness coding in the auditory system
Pitch and loudness coding in the auditory system is how frequency and intensity are represented via cochlear place codes and phase-locked spike timing, which fails above a few kHz.
Prestin
Prestin (SLC26A5) is the motor protein of cochlear outer hair cells, driving voltage-dependent electromotility for cochlear amplification. Named from Italian 'presto'; its anion transport, voltage sensing, and 2021 structures distinguish it from other SLC26 transporters.
Shepard tone
Shepard tone: auditory illusion by Roger Shepard (1964) of octave-spaced components under a fixed bell-shaped envelope, heard as endlessly rising or falling pitch; basis of the Risset glissando, tritone paradox, and film and game sound design.
Sound localization
Sound localization: identifying a sound's direction and distance using interaural time and level differences plus pinna spectral (HRTF) cues; duplex theory, precedence effect, hearing-device limits, and animal comparisons.
Spatial audio
Spatial audio is a family of recording and playback techniques that let listeners perceive sound sources in three-dimensional space, most commonly on headphones using head-related transfer functions.
Spiral ganglion
The spiral ganglion is a group of sensory neurons in the cochlea of the inner ear that relays sound information from hair cells to the brainstem.
Stapes
Stapes: smallest bone of the human body, the third middle-ear ossicle, footplate seated in the oval window; discovered by Ingrassia in 1546 and central to otosclerosis surgery.
Superior olivary complex
Superior olivary complex (SOC), or superior olive: cluster of auditory nuclei in the caudal pontine tegmentum, first site of binaural convergence; MSO computes interaural time differences, LSO level differences, for sound localization.
Tensor tympani muscle
Tensor tympani (musculus tensor tympani), a small middle-ear muscle innervated by CN V3, tenses the eardrum via the malleus, participates in the middle ear muscle reflex, and causes tensor tympani syndrome when it contracts involuntarily.
Ventral cochlear nucleus
Ventral cochlear nucleus (VCN), first relay of the central auditory system in the brainstem, subdivided into AVCN and PVCN; its octopus, bushy, and stellate cells run parallel timing and sound-localization pathways.