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Apheresis and extracorporeal blood therapies

14 articles

Artificial Liver

Artificial liver, or extracorporeal liver support: MARS, SPAD, Prometheus, plasma exchange, and bioartificial hepatocyte devices that temporarily filter blood in liver failure to bridge patients to transplant or recovery; survival benefit unproven except plasma exchange in ACLF.

Blood purification

Blood purification: extracorporeal therapies (hemodialysis, hemofiltration, apheresis, hemoperfusion, immunoadsorption) that remove toxins and pathogens from blood; also the Karger nephrology journal Blood Purification, ISSN 0253-5068, founded 1983.

Cytapheresis

Cytapheresis is a therapeutic apheresis procedure that selectively removes specific blood cells, such as white cells, platelets, or red cells, while returning the remaining blood to the patient.

Erythrocytapheresis

Erythrocytapheresis is an apheresis procedure in which a device removes a patient's red blood cells and replaces them with donor cells, most often to treat sickle cell disease.

Extracorporeal carbon dioxide removal

Extracorporeal carbon dioxide removal (ECCO2R) is a critical care technique that removes carbon dioxide from blood via a membrane, easing ventilation in severe ARDS and COPD.

Extracorporeal photopheresis

Extracorporeal photopheresis, also called photopheresis, is an immunomodulatory therapy in which white blood cells are treated with a drug and UVA light outside the body, then reinfused.

Hemoadsorption

Hemoadsorption is an extracorporeal blood purification therapy in which blood passes through a cartridge of adsorbent beads to remove inflammatory mediators, endotoxin, or toxins, aiming to moderate sepsis, drug toxicity, and poisoning.

Hemoperfusion

Hemoperfusion is an extracorporeal treatment that passes anticoagulated blood through a column of activated charcoal or resin beads to remove poisons, toxins, and inflammatory mediators.

Immunoadsorption

Immunoadsorption is an extracorporeal apheresis technique that selectively removes immunoglobulins and immune complexes from plasma, sparing albumin and coagulation factors, and is used in autoantibody-mediated neurological, cardiac, and kidney diseases and transplant desensitization.

LDL apheresis

LDL apheresis is an extracorporeal treatment that removes LDL cholesterol and lipoprotein(a) from the blood, used for severe familial hypercholesterolemia uncontrolled by drugs, with sessions repeated weekly or biweekly.

Leukapheresis

Leukapheresis (leukocytapheresis) is an apheresis procedure that removes white blood cells from circulated blood and returns the rest. Used for hyperleukocytosis cytoreduction, stem cell and CAR T-cell collection; main risk is citrate-induced hypocalcemia.

Plasma exchange

Plasma exchange, also called therapeutic plasma exchange or plasmapheresis, is a procedure that removes a patient's plasma and replaces it with albumin or donor plasma.

Sorption Detoxification

Sorption detoxification, or hemoperfusion (hemoadsorption), removes toxins by passing blood over charcoal, resin, or polymer adsorbents; used for poisoning, uremic toxins, liver failure, and sepsis, complementing rather than replacing dialysis.

Therapeutic apheresis

Therapeutic apheresis is a medical procedure that removes specific blood components, such as plasma, cells, or lipids, from a patient's circulation to treat disease. Its defining procedure is therapeutic plasma exchange.