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Perioperative hemodynamic and fluid management

9 articles

Acute normovolemic hemodilution

Acute normovolemic hemodilution (ANH) is a low-cost blood conservation technique performed in the operating room: blood is withdrawn after anesthesia induction and reinfused during or after surgery.

Autologous blood transfusion

Autologous blood transfusion is the return of a patient's own previously collected blood instead of donor blood, used in cardiac, orthopedic, trauma, and obstetric surgery through techniques such as cell salvage.

Autotransfusion

Autotransfusion is a clinical procedure that collects blood a patient loses during surgery or trauma and reinfuses it, most commonly with a device called a cell saver.

Bloodless Medical and Surgical Procedures

Bloodless medical and surgical procedures, also called transfusion-free medicine or patient blood management, provide care without allogeneic blood transfusion via anemia treatment, blood loss minimization, and oxygenation optimization, pioneered by Denton Cooley in 1962 for Jehovah's Witnesses.

Goal-directed fluid therapy

Goal-directed fluid therapy (GDFT) is a perioperative strategy in which intravenous fluids are given according to real-time hemodynamic measurements, aiming to optimize cardiac output and tissue oxygen delivery.

Hemodilution

Hemodilution is the deliberate dilution of a patient's blood to reduce transfusions. In acute normovolemic hemodilution, blood is withdrawn after anesthesia and reinfused after surgery.

HEMOPEC trial

HEMOPEC (NCT07070973) is a pilot trial at Gemelli in Rome testing AI-guided Assisted Fluid Management and Hypotension Prediction Index against goal-directed therapy during cytoreductive surgery with HIPEC for ovarian cancer, 52 women, 2025-2027.

Induced hypotension

Induced hypotension, also called deliberate or controlled hypotension, is an anesthetic technique that lowers blood pressure during surgery to reduce blood loss and improve the surgical field.

Intraoperative blood salvage

Intraoperative blood salvage, also called cell salvage, is a perioperative technique that collects blood lost during surgery, washes the red cells, and returns them to the patient, reducing donor transfusions.