edgepedia

Cytology and cytopathology

9 articles

Fingerstick

A fingerstick is a minimally invasive blood sampling method in which a lancet pricks the fingertip for a small drop of capillary blood, most often for glucose testing.

Genetic carrier screening

Genetic carrier screening tests asymptomatic people for one copy of a gene variant linked to recessive or X-linked disorders, so reproductive risk can be assessed before or during pregnancy.

HPV self-collection

HPV self-collection is a cervical cancer screening method in which a person collects their own vaginal sample, tested for 14 high-risk HPV types as primary screening.

Hydrogen breath test

The hydrogen breath test is a non-invasive diagnostic procedure measuring hydrogen and methane in exhaled air after a sugar substrate, detecting carbohydrate malabsorption or small intestinal bacterial overgrowth.

IgM antibody-capture ELISA

The IgM antibody-capture ELISA (MAC-ELISA) is a serologic immunoassay that first captures all of a patient's IgM antibodies, then detects virus-specific IgM among them, giving presumptive evidence of recent infection from one sample.

Multigene assay

A multigene assay is a diagnostic test combining the expression of multiple genes in a tumor into one score, used most often to guide chemotherapy decisions in early breast cancer.

Non-invasive prenatal screening

Non-invasive prenatal screening, also called NIPT or cfDNA screening, is a maternal blood test analyzing fetal DNA to screen for chromosomal abnormalities like Down syndrome from about 10 weeks of pregnancy.

Nucleic acid amplification test

A nucleic acid amplification test (NAAT) is a diagnostic method that detects a pathogen by copying its DNA or RNA many times, most commonly using PCR, and reports a qualitative or quantitative result.

SEREX

SEREX (serological analysis of recombinant cDNA expression libraries) is a tumor immunology method that screens tumor cDNA expression libraries with patient serum to identify tumor antigens like NY-ESO-1.