edgepedia

Point-of-care and rapid testing

12 articles

Antigen bead assay

An antigen bead assay is a multiplex immunoassay in which antigens are coupled to color-coded microspheres to detect and semi-quantify antibodies in serum, chiefly anti-HLA antibodies.

Array comparative genomic hybridization

Array comparative genomic hybridization, or array CGH, is a cytogenetic method that detects DNA copy-number gains and losses genome-wide, with far finer resolution than karyotyping.

Blood glucose monitoring

Blood glucose monitoring is the measurement of glucose in blood or interstitial fluid, using laboratory tests, fingerstick meters, and continuous glucose monitors to guide diabetes diagnosis and insulin dosing.

Contour Next

Contour Next is a family of blood glucose monitoring systems, with meters and test strips made by Ascensia Diabetes Care, introduced in 2012 as the successor to Bayer's CONTOUR meters.

ctDNA assay

A ctDNA assay is a blood-based diagnostic test that detects circulating tumor DNA released by tumors, used to select therapy, detect molecular residual disease, and monitor relapse.

Fluorescence polarization immunoassay

A fluorescence polarization immunoassay (FPIA) is a homogeneous competitive immunoassay that quantifies small analytes like drugs and hormones in minutes, used in therapeutic drug monitoring and food testing.

Metabolic screening

Metabolic screening is testing of newborn heel-prick blood spots, mostly by tandem mass spectrometry, to detect treatable inborn errors of metabolism such as PKU and MCADD before symptoms appear.

Noninvasive prenatal testing

Noninvasive prenatal testing, also known as Noninvasive Prenatal Screening, is a maternal blood test that screens for fetal chromosomal abnormalities. It is a screening test, not a diagnostic one.

Rapid diagnostic test

A rapid diagnostic test, or RDT, for malaria is a point-of-care immunochromatographic strip that detects Plasmodium antigens in finger-prick blood, giving results in about 15 to 30 minutes.

Reagent Strips

Reagent strips are chemically impregnated strips for detecting substances, chiefly urine dipsticks and blood glucose strips; history runs from Maumené's 1850 wool strip through Pavy and Oliver's 1880s dry chemistry to Clinistix (1956) and Multistix.

RET rearrangement analysis

RET rearrangement analysis is a molecular diagnostic test that detects RET gene fusions in tumors, most often papillary thyroid carcinoma and non-small-cell lung cancer, guiding treatment with selective RET inhibitors.

Urinalysis

Urinalysis is a laboratory test examining the physical, chemical, and microscopic properties of urine to detect kidney disease, urinary tract infection, liver disease, and metabolic disorders such as diabetes.