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Provocation, allergy and endocrine challenge testing

29 articles

10-2 visual field testing

10-2 visual field testing is an automated perimetry program measuring light sensitivity across the central 10° of vision, used to detect and monitor glaucoma and hydroxychloroquine retinopathy.

Adrenal Cortex Function Tests

Adrenal cortex function tests: ACTH (cosyntropin) stimulation test, insulin tolerance, CRH, and metyrapone tests for adrenal insufficiency, plus dexamethasone suppression testing for Cushing's syndrome, with cortisol and ACTH cutoffs.

Artemisia annua pollen allergen skin prick test solution

Artemisia annua pollen allergen skin prick test solution (黄花蒿花粉变应原皮肤点刺液) is an NMPA-approved 2023 diagnostic biologic by Zhejiang Wolwo for skin prick testing, 33333 DU/ml, aiding diagnosis of Artemisia pollen allergy.

Cough detection

Cough detection is the automated identification of cough events in audio or sensor recordings, turning cough into an objective count; systems like the Leicester Cough Monitor and VitaloJAK support 24-hour monitoring.

Digit symbol substitution test

The digit symbol substitution test (DSST) is a timed neuropsychological test of processing speed, in which a person copies geometric symbols beneath matching digits using a key.

Electrocardiographic monitoring

Electrocardiographic monitoring is the continuous or intermittent recording of the heart's electrical activity over hours to years, using Holter monitors, patches, telemetry, and implanted devices.

Electroneurography

Electroneurography (ENoG), also called electroneuronography, is a neurophysiological test that electrically stimulates a peripheral nerve and records the evoked muscle response to quantify nerve function.

Endocrine Diagnostic Techniques

Endocrine diagnostic techniques: biochemical assays, dynamic stimulation and suppression tests, imaging, and venous sampling used to diagnose hormone disorders such as PPGL, Cushing syndrome, and adrenal insufficiency.

Galvanic vestibular stimulation

Galvanic vestibular stimulation is a non-invasive technique that passes small currents through electrodes behind the ears to modulate the vestibular nerve, evoking sway and sensations of self-motion.

German cockroach (Blattella germanica) allergen skin prick test solution

German cockroach (Blattella germanica) allergen skin prick test solution (德国小蠊变应原皮肤点刺液), Wolwo Bio-Pharmaceutical's NMPA-approved 7000 DU/ml in-vivo diagnostic for type I cockroach allergy, sensitivity 91.63%, specificity 85.45%.

Humulus scandens (Japanese hop) pollen allergen skin prick test solution

葎草花粉变应原皮肤点刺液, Skin Prick Solution for Humulus japonicus (Japanese hop) pollen allergens: Wolwo Biotech's NMPA-approved (国药准字 S20230025, 2023) 3333 DU/ml skin prick reagent aiding diagnosis of Humulus pollen type I allergy in China.

Lactose Tolerance Test

Lactose tolerance test (lactose tolerance blood test): blood glucose measured after a 50 g oral lactose load to detect lactase deficiency; glucose rise under 20 mg/dL is abnormal; largely replaced by the hydrogen breath test.

Medial branch block

A medial branch block is a diagnostic injection of local anesthetic onto the nerves supplying spinal facet joints, testing whether those joints are the source of back or neck pain.

Nasal Provocation Tests

Nasal provocation test, also called nasal allergen challenge (NAC) or NAPT, applies allergen to the nasal mucosa to confirm allergic rhinitis, local and occupational rhinitis, and immunotherapy candidacy; EAACI 2018 standardized it bilaterally at 0.1 mL per nostril.

Oral food challenge

An oral food challenge is a medical test in which a patient eats increasing amounts of a suspected food under supervision to confirm or rule out a food allergy.

Ovulation Detection

Ovulation detection determines whether and when ovulation occurs, via urine LH kits, ultrasound, serum progesterone, basal body temperature, cervical mucus, and apps or wearables; distinct from ovulation prediction and calendar rhythm methods.

Penicillin allergy testing

Penicillin allergy testing is the diagnostic evaluation of patients carrying a penicillin allergy label, using structured history, skin testing, and observed oral challenge to confirm or remove the label.

Pituitary-Adrenal Function Tests

Pituitary-adrenal function tests, including the 250 µg and 1 µg ACTH (cosyntropin/Synacthen) stimulation tests, insulin tolerance test, metyrapone test, and morning cortisol, evaluate the hypothalamic-pituitary-adrenal axis to diagnose primary and secondary adrenal insufficiency.

Plane tree (Platanus) pollen allergen skin prick test solution

悬铃木花粉变应原皮肤点刺液 (Platanus pollen allergen skin prick solution), Wolwo Bio-Pharmaceutical's Class 1 biological product approved by China's NMPA in December 2024 (国药准字S20240057); skin prick test reagent aiding diagnosis of Platanus pollen type I allergy, sensitivity 91.13%, specificity 88.39%.

Pulmonary artery pressure monitoring

Pulmonary artery pressure monitoring is hemodynamic monitoring in which a small implantable sensor in a pulmonary artery measures blood pressure remotely, allowing heart failure treatment to be adjusted before congestion worsens.

Skin Test End-Point Titration

Skin test end-point titration (SET, serial dilution end-point titration, intradermal dilutional testing) is a quantitative intradermal allergy test using increasing allergen dilutions to find a wheal endpoint, developed by Herbert J. Rinkel, used to set immunotherapy doses.

Skin testing

Skin testing is an in vivo allergy diagnostic method in which allergens applied to or injected into the skin provoke reactions, identifying immediate IgE-mediated allergy or delayed contact allergy.

Skin Tests

Skin tests: prick, intradermal, and patch tests that expose skin to allergens or drugs to diagnose immediate (IgE) or delayed hypersensitivity; prick test read at 15-20 minutes, pooled sensitivity 85% for allergic rhinitis.

Sleep study

A sleep study is a diagnostic test recording brain activity, breathing, blood oxygen, and body movement during sleep; attended in-lab polysomnography is the reference standard for diagnosing obstructive sleep apnea.

Symbol Digit Modalities Test

The Symbol Digit Modalities Test (SDMT) is a brief neuropsychological test of processing speed in which symbols are matched to digits, scored 0 to 110.

Tissue oximetry

Tissue oximetry is a noninvasive optical technique that measures oxygen saturation within tissue. It utilizes near-infrared spectroscopy to reflect the balance of oxygen supply and demand at the bedside.

Tuberculin skin test

The tuberculin skin test (TST) is a diagnostic test for tuberculosis infection in which tuberculin PPD is injected into the skin and the reaction is measured.

Voltage mapping

Voltage mapping is a cardiac electrophysiology technique in which a roving catheter records electrogram voltages across a heart chamber to identify scar and guide ablation.

Water deprivation test

The water deprivation test is a supervised endocrinology procedure that withholds all fluid intake to distinguish central diabetes insipidus, nephrogenic diabetes insipidus, and primary polydipsia, often followed by desmopressin.