edgepedia

Functional and advanced MRI analysis

23 articles

Arterial spin labeling

Arterial spin labeling is a magnetic resonance imaging technique that measures cerebral blood flow by magnetically labeling arterial blood water, requiring no injected contrast agent.

Blood-oxygen-level-dependent imaging

Blood-oxygen-level-dependent (BOLD) imaging is a functional MRI technique that maps brain activity indirectly through blood oxygenation changes, first demonstrated by Seiji Ogawa at Bell Laboratories in 1990.

Brain volumetry

Brain volumetry is the measurement of volumes of brain structures such as the hippocampus, typically from MRI scans, used to quantify atrophy in dementia and epilepsy workups.

Diffusion kurtosis imaging

Diffusion kurtosis imaging (DKI) is an MRI technique that quantifies non-Gaussian water diffusion in tissue, extending diffusion tensor imaging; it was introduced by Jens Jensen and colleagues in 2005.

Diffusion spectrum imaging

Diffusion spectrum imaging (DSI) is a magnetic resonance imaging method that reconstructs water diffusion without a tissue model, resolving crossing fibers that diffusion tensor imaging cannot.

Diffusion tensor imaging

Diffusion tensor imaging (DTI) is an MRI technique that estimates water diffusion per voxel, producing anisotropy maps and tract reconstructions used for stroke, brain tumors, and surgical planning.

Diffusional kurtosis imaging

Diffusional kurtosis imaging (DKI) is a diffusion MRI method that quantifies non-Gaussian water diffusion to probe tissue microstructure, introduced by Jens H. Jensen and colleagues in 2005.

Dynamic functional connectivity

Dynamic functional connectivity (dFC) is a neuroimaging analysis method that measures how statistical dependence between brain regions' activity changes over the course of an fMRI scan.

EEG-fMRI

EEG-fMRI is a multimodal neuroimaging method that records EEG and functional MRI at the same time, combining EEG's millisecond timing with fMRI's spatial resolution, first demonstrated in 1993.

Functional connectivity analysis

Functional connectivity analysis measures statistical relationships, most commonly temporal correlations, between activity in different brain regions, typically from resting-state fMRI, and is used in clinical research on brain disorders.

Functional connectivity MRI

Functional connectivity MRI, also called resting-state fMRI, is an MRI method that maps brain networks by measuring correlations of spontaneous BOLD signal fluctuations between regions, without any task or stimulus.

Intravoxel incoherent motion imaging

Intravoxel incoherent motion (IVIM) imaging is a diffusion-weighted MRI technique, introduced by Le Bihan in 1986, that separates microvascular perfusion from true water diffusion without contrast agents.

Lesion network mapping

Lesion network mapping is a neuroimaging analysis method that links brain lesion locations to the symptoms they cause by mapping each lesion onto a normative human connectome.

Q-space trajectory imaging

Q-space trajectory imaging (QTI) is a diffusion MRI method that uses time-varying gradients and a tensor distribution model to measure tissue microstructure properties like microscopic anisotropy.

Resting-state fMRI

Resting-state fMRI (rs-fMRI) is a functional MRI method that maps functional connectivity between brain regions by measuring spontaneous BOLD signal fluctuations while the subject performs no task.

Restriction spectrum imaging

Restriction spectrum imaging (RSI) is a magnetic resonance imaging technique that separates restricted, hindered, and free water diffusion, quantifying tissue microstructure for brain tumor and prostate cancer diagnosis.

Source imaging

Source imaging, or electrophysiological source imaging (ESI), reconstructs 3D maps of brain currents from EEG or MEG with millisecond resolution, used clinically to localize epileptic foci.

Spatial normalization (neuroimaging)

Spatial normalization is a neuroimaging preprocessing method that warps brain scans from different subjects into a common reference space, underpinning voxel-based morphometry and fMRI group analysis.

Spinal fMRI

Spinal fMRI is a functional MRI method measuring spinal cord neural activity indirectly through task-evoked BOLD signals, first reported in the human cervical cord in 1996.

Statistical parametric mapping

Statistical parametric mapping (SPM) is a framework and MATLAB package that applies statistical tests at every voxel of PET or fMRI data to map significant brain activity.

Tensor tractography

Tensor tractography is a diffusion MRI technique that reconstructs white matter fiber pathways as streamlines by following the principal diffusion direction voxel-by-voxel through the brain.

Tractography

Tractography, also called MRI tractography, is a computational method that reconstructs the brain's white-matter fiber pathways from diffusion MRI data, first demonstrated in vivo in 1999 and used mainly for preoperative planning.

Tractometry

Tractometry is a diffusion MRI analysis method that quantifies diffusion-derived tissue metrics along reconstructed white matter tracts, producing detailed along-tract profiles used to study development, disease, and the visual system.