edgepedia

Ophthalmic and optical imaging

30 articles

Coherence elastography

Coherence elastography, usually called optical coherence elastography (OCE), is an imaging technique that measures tissue stiffness at micrometer resolution using optical coherence tomography, with the cornea as its leading application.

Corneal densitometry

Corneal densitometry is an ophthalmic imaging measurement that quantifies backscattered light from the cornea using a rotating Scheimpflug camera, used to follow corneal opacity in keratoconus and after cross-linking.

Corneal tomography

Corneal tomography is an ophthalmic imaging method that reconstructs a 3D model of the cornea and anterior segment, and the current standard for detecting keratoconus and screening refractive surgery candidates.

Corneal topography

Corneal topography is a non-invasive, computer-aided imaging method that maps the front surface of the cornea, used to diagnose keratoconus and screen candidates for laser refractive surgery.

Doppler optical coherence tomography

Doppler optical coherence tomography, also called optical Doppler tomography, is an imaging method combining OCT with Doppler shift measurement to quantify blood flow velocity in living tissue.

Fundus autofluorescence imaging

Fundus autofluorescence (FAF) imaging is a noninvasive ophthalmic technique recording the fundus's natural fluorescence, used to assess retinal health in macular degeneration and inherited retinal dystrophies.

Fundus fluorescein angiography

Fundus fluorescein angiography (FFA) is an ophthalmic imaging method that injects sodium fluorescein intravenously and photographs the retina over time to visualize blood flow, capillary perfusion, and barrier leakage.

Fundus photography

Fundus photography is an ophthalmic imaging method that uses a fundus camera to photograph the retina, optic nerve, and macula, detecting diabetic retinopathy, glaucoma, and macular degeneration.

Indocyanine green

Indocyanine green (ICG) is a near-infrared fluorescent dye approved in the United States in 1959 and used as an optical imaging agent in surgery and ophthalmic angiography.

Indocyanine green angiography

Indocyanine green angiography (ICGA) is an imaging method that injects fluorescent indocyanine green dye intravenously and records its near-infrared fluorescence to visualize blood flow in the choroid and in surgical tissue.

iPhot study

iPhot study (NCT01546181), an INSERM observational follow-up study of adaptive optics retinal imaging in Paris (2010-2017), using the rtx1 camera to quantify photoreceptor density and retinal microstructures in health and disease.

Laser Doppler imaging

Laser Doppler imaging (LDI) is a non-contact optical technique that maps blood perfusion in skin and superficial tissue by scanning a low-power laser beam across the surface.

Laser speckle flowgraphy

Laser speckle flowgraphy (LSFG) is a noninvasive optical imaging method that maps blood flow in the ocular fundus by measuring how moving red blood cells blur a laser speckle pattern.

Meibography

Meibography is an infrared imaging technique that photographs the meibomian glands inside the everted eyelids to detect gland loss in meibomian gland dysfunction and dry eye.

Moire Topography

Moire topography (Moiré topography, shadow and projection moiré) is a radiation-free optical 3D morphometry method using interference fringes, used since 1970 mainly for scoliosis screening; moderate evidence supports reliability but not superiority over radiography.

Near-infrared fluorescence imaging

Near-infrared fluorescence imaging, also called infrared fluorescence imaging, is an optical technique using fluorescent probes to visualize vessels, bile ducts, lymphatics, and tumors during diagnosis and surgery.

Ophthalmodynamometry

Ophthalmodynamometry (ODM) measures retinal vessel blood pressure by pressing on the eye while observing the central retinal vessels; developed by Bailliart (1923), used for carotid disease, later displaced by Doppler sonography.

Optical coherence tomography angiography

Optical coherence tomography angiography (OCTA) is a noninvasive imaging method that visualizes blood flow in the retinal and choroidal microvasculature without dye, commercially available since 2014.

Optical frequency domain imaging

Optical frequency domain imaging (OFDI), also known as swept-source OCT, is a high-speed form of optical coherence tomography introduced in 2003, used in coronary imaging and gastrointestinal endoscopy.

Optical Imaging

Optical imaging: biomedical imaging using light interaction (scattering, absorption, fluorescence) with tissue, from microscopy to OCT, DOT, and photoacoustic methods; defined by MeSH in 2013, limited by scattering to a depth-resolution trade-off, with FDA-approved agents like ICG.

Optoretinography

Optoretinography (ORG) is a dye-free optical imaging method that measures how photoreceptors in the living retina respond to light, detecting dysfunction in diseases such as retinitis pigmentosa.

Polarization-sensitive optical coherence tomography

Polarization-sensitive optical coherence tomography (PS-OCT) is an OCT variant that measures backscattered light's polarization, mapping birefringence in collagen and nerve fibers for glaucoma, burn, and scar assessment.

Scanning laser ophthalmoscopy

Scanning laser ophthalmoscopy (SLO) is an ophthalmic imaging method that builds a video image of the retina with a scanning laser, using about 1/1000 of the light of conventional ophthalmoscopy.

Scanning Laser Polarimetry

Scanning laser polarimetry (SLP, GDx) is a noninvasive eye imaging method measuring retinal nerve fiber layer thickness via polarization retardation of a 780 nm laser, used mainly for glaucoma diagnosis and monitoring.

Scheimpflug imaging

Scheimpflug imaging is an ophthalmic technique in which a tilted camera photographs slit cross-sections of the anterior eye, building a 3D corneal model used to detect keratoconus.

Scheimpflug tomography

Scheimpflug tomography is an ophthalmic imaging method in which a rotating camera captures cross-sections of the cornea, building a 3D model used mainly to detect keratoconus before refractive surgery.

Spatial frequency domain imaging

Spatial frequency domain imaging (SFDI) is a noncontact, wide-field optical technique that projects sinusoidal light patterns onto tissue to map absorption, scattering, hemoglobin, and oxygen saturation, reported in 2005.

Speckle contrast imaging

Speckle contrast imaging, also known as LASCA or LSCI, is a label-free optical technique mapping blood flow in tissue from laser speckle blurring, first published in 1981.

Specular microscopy

Specular microscopy is an ophthalmic imaging technique that photographs the corneal endothelium in vivo, measuring endothelial cell density for diagnosing corneal disease and planning corneal surgery.

Videoangiography

Videoangiography is an imaging method that records blood flow on video in real time after injection of a fluorescent dye such as fluorescein or ICG.