50 articles
Autologous blood injection
Autologous blood injection (ABI) is a procedure in which a patient's own blood is injected into an injured tendon to stimulate healing, used mainly for tennis elbow.
Bolus injection
A bolus injection is a dose of a substance given by a single rapid intravenous injection, typically over 1 to 30 minutes, producing an immediate peak plasma concentration.
Botulinum toxin injection
Botulinum toxin injection is a medical treatment in which botulinum neurotoxin is injected into muscles or glands, temporarily reducing muscle activity or secretion for many conditions.
Cannulation (medicine)
Cannulation is the insertion of a cannula into a blood vessel, body cavity, or organ to deliver fluids and medications, sample blood, monitor hemodynamics, or drain structures.
Chemical Hypophysectomy
Chemical hypophysectomy, or pituitary neuroadenolysis, destroys the pituitary by stereotactic trans-sphenoidal alcohol injection to relieve refractory cancer pain; developed by Greco and Moricca in the late 1950s, it gave roughly 75-85% relief but was displaced by intrathecal opioids and radiosurgery.
Cutaneous Administration
Cutaneous administration delivers drugs through the skin, spanning topical local action and transdermal systemic delivery via patches. Key facts: stratum corneum barrier, sub-500 Da drug criteria, 1979 scopolamine first patch, enhancement methods.
Dextrose prolotherapy
Dextrose prolotherapy is an injection therapy in which hypertonic dextrose solution, typically 12.5% to 25%, is injected into tendons, ligaments, or joints to treat chronic musculoskeletal pain.
Drug Instillation
Drug instillation places liquid medication drop by drop or in measured volume into a body cavity: eye drops, nasal drops, ear drops, and catheter-based intravesical bladder therapy, with pharmacokinetics and evidence.
Epidural Blood Patch
Epidural blood patch (EBP): injection of a patient's own blood, typically 10–20 mL, into the epidural space to seal dural punctures and CSF leaks; first reported by Gormley in 1960; treats post-dural puncture headache and spontaneous intracranial hypotension.
Gastrointestinal intubation
Gastrointestinal intubation is the passage of a flexible tube through the nose or mouth into the stomach or small intestine, used for enteral feeding, medication, or draining gastric contents.
Gavage
Gavage is the delivery of liquid nutrition or medication through a tube passed into the stomach, by nose or mouth, used for feeding, gastric decompression, and rodent dosing.
Home Infusion Therapy
Home infusion therapy is the administration of medications, fluids, or nutrients in a patient's home, typically intravenously or subcutaneously, for infections, immune disorders, and cancer, often at lower cost than hospital care.
Hyaluronic acid injection
A hyaluronic acid injection delivers hyaluronan gel into tissue, either into the knee joint to relieve osteoarthritis pain or into facial soft tissue to fill lines and restore volume.
Hypodermoclysis
Hypodermoclysis, or subcutaneous fluid infusion, rehydrates mildly to moderately dehydrated patients, especially older adults and palliative care patients, when venous access is difficult; about 3 L daily at two sites.
Inhalation Administration
Inhalation Administration (MeSH Administration, Inhalation) is drug delivery by the respiratory route via pMDIs, dry powder inhalers, soft mist inhalers, and nebulizers; first-line for asthma and COPD, with no proven clinical advantage of any device over the cheapest pMDI.
Inhalational administration
Inhalational administration is a route of drug delivery in which medication is breathed into the lungs as an aerosol or dry powder via inhalers or nebulizers.
Injection (medicine)
Injections: introduction of substances into the body with a needle and syringe, a parenteral drug and vaccine route (intravenous, intramuscular, subcutaneous, intradermal). At least 16 billion given yearly worldwide; hypodermic injection dates to 1853.
Intra-arterial injection
Intra-arterial injection delivers a drug or contrast agent directly into an artery feeding an organ or tumor, used for chemotherapy, thrombolysis, and embolization since 1950.
Intra-articular injection
An intra-articular injection, also called an intra-articular corticosteroid injection, places medication such as a corticosteroid or local anesthetic into a joint, relieving arthritis pain for weeks to months.
Intracavernosal injection
Intracavernosal injection (ICI) is a urological procedure in which a vasoactive drug is injected into the corpora cavernosa of the penis, a second-line erectile dysfunction treatment after PDE5 inhibitors.
Intracavernous injection
Intracavernous injection is a procedure that injects vasoactive drugs such as alprostadil directly into the corpora cavernosa of the penis to produce an erection for treating erectile dysfunction.
Intracerebral administration
Intracerebral administration is a drug delivery route in which a therapeutic agent is injected or infused directly into brain tissue, bypassing the blood–brain barrier, mainly through convection-enhanced delivery.
Intracolonic administration
Intracolonic administration is a route of drug delivery in which the dose is placed directly into the colon, typically through an enema or a colonoscopically guided catheter.
Intradermal injection
Intradermal injection delivers a small volume of drug or vaccine into the dermis, used for tuberculin and allergy skin tests and for dose-sparing vaccination against rabies, influenza, and mpox.
Intralesional Infusions
Intralesional infusions (MeSH: Infusions, Intralesional) deliver medication directly into localized lesions via gravity flow or infusion pumps, distinct from intralesional injections; used in melanoma (T-VEC, PV-10), keloids, and skin disease.
Intralesional injection
An intralesional injection delivers medication directly into a skin lesion or other diseased tissue rather than the circulation, most often triamcinolone, a mainstay treatment for keloid scars and warts.
Intralymphatic Injections
Intralymphatic injections deliver drugs or allergens directly into lymph nodes or lymphatic vessels (endolymphatic injection). Main use is intralymphatic immunotherapy (ILIT), three ultrasound-guided node injections replacing years of allergy shots, plus experimental cancer vaccine delivery.
Intraperitoneal injection
Intraperitoneal injection is a drug administration route in which medication is delivered into the peritoneal cavity, used clinically for chemotherapy of peritoneal surface malignancies and routinely in laboratory rodents.
Intratumoral injection
Intratumoral injection is an oncology drug delivery method injecting agents directly into a tumor for high local concentrations and low systemic exposure, used chiefly for immunotherapies like oncolytic viruses and T-VEC.
Intratympanic injection
Intratympanic injection is an ear procedure in which drugs such as steroids or gentamicin are injected through the eardrum into the middle ear, diffusing into the inner ear.