4 articles
Dilated cardiomyopathy
Dilated cardiomyopathy (DCM), also called congestive or idiopathic cardiomyopathy, is heart-muscle disease with left ventricular dilatation and systolic dysfunction not explained by coronary, hypertensive, or valvular disease; prevalence about 1 in 250 adults, genetic in 25–40% of cases (TTN, LMNA, DSP, FLNC).
Dilated cardiomyopathy with ataxia
Dilated cardiomyopathy with ataxia (DCMA, 3-methylglutaconic aciduria type V) is a rare autosomal recessive mitochondrial disease from DNAJC19 mutations, concentrated in the Dariusleut Hutterite population, causing early-onset cardiomyopathy, long QT, cerebellar ataxia, and growth failure.
Dilated cardiomyopathy-hypergonadotropic hypogonadism syndrome
Dilated cardiomyopathy-hypergonadotropic hypogonadism syndrome, also called Malouf, Najjar, or cardiogenital syndrome (ORPHA:2229, OMIM 212112), is an ultra-rare disorder combining dilated cardiomyopathy with primary hypergonadotropic hypogonadism, often LMNA-related, prevalence under 1 per million.
Familial isolated dilated cardiomyopathy
Familial isolated dilated cardiomyopathy (FDC, ORPHA:154), also called familial or idiopathic DCM: inherited left ventricular dilation with systolic dysfunction, usually autosomal dominant, genetically identified in 30-40% of cases, most often TTN or LMNA.