17 articles
Aseptic myocarditis of newborn
Aseptic myocarditis of newborn (新生儿无菌性心肌炎), ICD-11 1D85.3 under viral carditis, is nonbacterial neonatal heart-muscle inflammation, usually enteroviral (Coxsackie B), with nonspecific symptoms and high neonatal mortality.
BASEL-PMI study
BASEL-PMI (NCT02573532) is a prospective multicenter study from University Hospital Basel screening high-risk noncardiac surgery patients for perioperative myocardial injury, defining PMI by absolute troponin rise and reporting etiology-specific mortality.
Blunt cardiac injury
Blunt cardiac injury (BCI), formerly myocardial contusion, is heart injury from blunt chest trauma, mainly motor vehicle collisions. Screening uses admission ECG plus troponin I; both normal rule out BCI.
Cardiotoxicity
Cardiotoxicity, or cancer therapy-related cardiac dysfunction (CTRCD), is heart injury from chemotherapy, targeted agents, immune therapies, or radiation. Key facts: anthracycline dose-response, type I vs type II, LVEF/GLS/troponin monitoring, dexrazoxane prevention.
Coxsackie carditis
Coxsackie carditis: heart inflammation (myocarditis, pericarditis) caused by coxsackievirus B, chiefly CVB3, the most common cause of infectious myocarditis; injury is viral then autoimmune; treatment supportive.
Eosinophilic myocarditis
Eosinophilic myocarditis (EM), also called Löffler endomyocarditis in its chronic form, is a rare inflammatory cardiomyopathy with eosinophilic infiltration of the heart muscle, caused by hypersensitivity, EGPA, HES, parasites, or idiopathic factors, and treated with cause-specific therapy plus corticosteroids.
Giant-cell myocarditis
Giant-cell myocarditis (GCM), also called giant cell myocarditis, is a rare T cell–mediated autoimmune inflammation of the heart causing fulminant failure and arrhythmias; diagnosed by endomyocardial biopsy, treated with combined immunosuppression, and often requiring transplant.
Hypersensitivity myocarditis
Hypersensitivity myocarditis (allergic myocarditis, ICD-11 BC42.2) is a drug- or vaccine-triggered eosinophilic inflammation of the heart muscle, diagnosed by endomyocardial biopsy, treated by drug withdrawal plus corticosteroids.
Infectious myocarditis
Infectious myocarditis (ICD-11 BC42.1), inflammation of the heart muscle from viral, bacterial, or parasitic antigens. Viruses predominate; parvovirus B19 and HHV-6 in high-income countries, dengue, HIV, malaria, and Chagas elsewhere.
Lyme carditis
Lyme carditis, heart inflammation from Borrelia burgdorferi in Lyme disease, causing fluctuating atrioventricular block; treated with oral or IV antibiotics, usually resolving in 1–6 weeks.
Myocarditis in children
Myocarditis in children is inflammation of the heart muscle, usually triggered by a virus, that can impair pumping; most children recover, but severe cases can cause heart failure.
Myocarditis in systemic autoimmune and inflammatory disease
Myocarditis in systemic autoimmune and inflammatory disease is inflammation of the heart muscle driven by diseases such as lupus and sarcoidosis, frequently subclinical and treated with immunosuppression.
Pixantrone
Pixantrone (Pixuvri) is an aza-anthracenedione chemotherapy for multiply relapsed or refractory aggressive non-Hodgkin B-cell lymphoma; EU-authorized 2012, expired 2024, designed for reduced cardiotoxicity.
Rheumatic myocarditis
Rheumatic myocarditis (ICD-10 I09.0, ICD-11 BC42.3) is heart muscle inflammation from autoimmune reaction to group A streptococcal infection in acute rheumatic fever, marked by Aschoff bodies, with debated clinical significance versus valvular disease.
Takotsubo cardiomyopathy
Takotsubo cardiomyopathy (broken heart syndrome, stress cardiomyopathy, apical ballooning) is a stress-triggered, transient left ventricular dysfunction mimicking heart attack, affecting mostly postmenopausal women, driven by catecholamine surges, with 4–5% in-hospital mortality and no specific proven treatment.
Viral carditis
Viral carditis (ICD-11 1D85; ICD-10 B33.2) is heart inflammation from viral infection, mainly Coxsackie B and other enteroviruses, presenting as myocarditis, pericarditis, or dilated cardiomyopathy.
Viral myocarditis
Viral myocarditis is inflammation of the heart muscle caused by a viral infection, most often parvovirus B19 or HHV-6 today, ranging from no symptoms to heart failure and sudden death.