17 articles
Adenocarcinoma of fallopian tube
Adenocarcinoma of the fallopian tube (primary fallopian tube carcinoma) is a rare epithelial cancer, 0.14–1.8% of genital malignancies, mostly serous, arising often from fimbrial STIC, staged and treated like ovarian cancer with surgery plus carboplatin-paclitaxel.
Adenocarcinoma of ovary
Adenocarcinoma of ovary (ovarian adenocarcinoma, ORPHA:213504, ICD-10 C56) is a malignant gland-forming epithelial ovarian tumor comprising five WHO histotypes, most commonly high-grade serous carcinoma, treated with surgery and platinum-taxane chemotherapy.
Carcinomas of ovary
Carcinomas of ovary (ICD-11 2C73.0), malignant epithelial ovarian tumors grouped with fallopian tube and primary peritoneal cancer; five WHO histotypes, high-grade serous most common, treated with surgery and platinum-taxane chemotherapy.
Clear cell adenocarcinoma of the ovary
Clear cell adenocarcinoma of the ovary (ovarian clear cell carcinoma, OCCC, ORPHA:398971) is a rare epithelial ovarian cancer, ~10% of EOC, linked to endometriosis, ARID1A/PIK3CA mutations, good early-stage prognosis, and platinum-resistant advanced disease.
Endometrioid adenocarcinoma of ovary
Endometrioid adenocarcinoma of ovary (ovarian endometrioid carcinoma, ICD-11 2C73.01): an epithelial ovarian cancer resembling endometrial adenocarcinoma, about 10% of primary ovarian carcinomas, endometriosis-associated, low grade, favorable prognosis.
Gynandroblastoma
Gynandroblastoma, a rare mixed ovarian sex cord-stromal tumor with both granulosa cell (female) and Sertoli-Leydig (male) differentiation; under 1% of sex cord tumors, often DICER1-mutated, FOXL2-wild-type, usually benign.
Malignant granulosa cell tumor of the ovary
Malignant granulosa cell tumor of the ovary (granulosa cell cancer, AGCT): rare estrogen-secreting sex cord stromal ovarian tumor, 2-5% of ovarian cancers, FOXL2 C134W mutation in ~95%, late recurrence, treated surgically.
Malignant mixed Müllerian tumor of the ovary
Malignant mixed Müllerian tumor of the ovary, also called ovarian carcinosarcoma or MMMT, is a rare biphasic ovarian cancer (1–4% of cases) mixing carcinomatous and sarcomatous cells, treated with cytoreductive surgery plus platinum chemotherapy, with poor prognosis.
Malignant Sertoli-Leydig cell tumor of the ovary
Malignant Sertoli-Leydig cell tumor of the ovary (androblastoma, arrhenoblastoma; ORPHA:99916): rare malignant sex cord-stromal ovarian tumor of young women, androgen-secreting with virilization, DICER1-mutated in 60%, treated by surgery plus risk-adapted chemotherapy.
Malignant teratoma of ovary
Malignant teratoma of ovary (immature teratoma) is a rare malignant ovarian germ cell tumor of young women, graded by immature neuroepithelium, treated with fertility-sparing surgery and BEP chemotherapy, with excellent survival.
Malignant tumor of fallopian tubes
Malignant tumor of fallopian tubes, or fallopian tube cancer, a rare gynecological carcinoma often arising near the fimbria and linked to BRCA mutations; treated like ovarian cancer with surgery and platinum chemotherapy.
Mucinous adenocarcinoma of ovary
Mucinous adenocarcinoma of ovary (ovarian mucinous adenocarcinoma, MOC), a rare 3–5% subtype of epithelial ovarian cancer; unilateral mucin-producing tumor, good early-stage prognosis, poor advanced-stage survival, expansile versus infiltrative WHO subtypes.
Ovarian dysgerminoma
Ovarian dysgerminoma is a rare malignant ovarian tumor arising from primordial germ cells, the most common malignant ovarian germ cell tumor, affecting mainly young women with a good prognosis.
Polyembryoma
Polyembryoma: rare malignant gonadal germ cell tumor dominated by embryoid bodies (embryonal carcinoma germ disc, amnion-like and yolk sac cavities); usually part of mixed germ cell tumor, teratoma most common companion; AFP and beta-hCG may be elevated.
Primary non-gestational choriocarcinoma of ovary
Primary non-gestational choriocarcinoma of ovary (NGCO), a rare malignant ovarian germ cell tumor producing hCG, arising without pregnancy, metastasizing to lung, liver, and brain, distinguished from gestational choriocarcinoma by DNA polymorphism analysis and treated with surgery plus BEP chemotherapy.
Primary peritoneal carcinoma
Primary peritoneal carcinoma (PPC, ORPHA:168829), a rare extra-ovarian cancer of the peritoneum resembling serous ovarian carcinoma; about 10% of pelvic serous carcinomas, mean age 60, treated with cytoreductive surgery plus platinum chemotherapy.
Small cell carcinoma of the ovary
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT), a rare aggressive ovarian cancer of young women, first described 1979, causing hypercalcemia in two-thirds of cases and driven by SMARCA4 loss.