PFKFB4
PFKFB4 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4), testis-origin glycolytic regulator enzyme producing fructose 2,6-bisphosphate; hypoxia-induced via HIF-1α, required for glioma and prostate cancer cell survival, targeted by inhibitor 5MPN.