14 articles
Alfred P. Fishman
Alfred P. Fishman was an American pulmonary physician-scientist at the University of Pennsylvania who organized the National Registry on Primary Pulmonary Hypertension and wrote a standard textbook.
Centrilobular emphysema
Centrilobular emphysema (centriacinar emphysema), smoking-linked emphysema starting at the center of the secondary pulmonary lobule, upper-lobe predominant, graded on CT as trace to advanced destructive, ICD-10 J43.2.
Chronic bronchiolitis
Chronic bronchiolitis (ICD-11 CA26) is chronic inflammatory and fibrotic injury of the small airways, caused by infection, inhalation injury, drugs, transplantation, connective tissue disease, or idiopathic factors, distinct from acute infantile bronchiolitis.
Chronic bronchitis
Chronic bronchitis is a condition marked by a productive cough on most days for at least three months in two consecutive years, usually caused by cigarette smoke.
Chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD), including emphysema and chronic bronchitis, is a progressive lung disease causing restricted airflow; third leading cause of death worldwide with 3.4 million deaths in 2023, diagnosed by spirometry FEV1/FVC ≤0.70.
Compensatory emphysema
Compensatory emphysema (ICD-11 CB40.4, ICD-10 J98.3) is overinflation of normal lung tissue when another portion is destroyed or removed, as after pneumonectomy, pneumonia, pleural effusion, or pneumothorax; unlike true emphysema it involves no alveolar destruction.
Diffuse panbronchiolitis
Diffuse panbronchiolitis (DPB, 弥漫性泛细支气管炎) is a rare idiopathic inflammatory lung disease of respiratory bronchioles, mainly affecting East Asians, marked by chronic sinusitis, cough, sputum, tree-in-bud HRCT nodules, and treatable with low-dose macrolides.
Emphysema
Emphysema, also called pulmonary emphysema, is a type of COPD in which alveolar walls are destroyed, mainly by smoking or alpha-1 antitrypsin deficiency; diagnosed by spirometry and CT, treated with bronchodilators, oxygen, and lung volume reduction.
FODEPOC study
FODEPOC (NCT05853081) is a Spanish observational cohort study at Hospital General Universitario Gregorio Marañón testing whether the FODE scale, replacing BMI with fat-free mass index in the BODE index, better predicts COPD exacerbations and mortality.
Idiopathic bronchiectasis
Idiopathic bronchiectasis is bronchiectasis, a chronic respiratory disease of permanently widened airways causing daily cough and sputum, with no identifiable cause after systematic testing; it is the largest category of non-cystic fibrosis bronchiectasis in adults.
MacLeod syndrome
MacLeod syndrome, or Swyer-James-MacLeod syndrome, is a rare acquired unilateral hyperlucent lung caused by postinfectious obliterative bronchiolitis in childhood, with air trapping, oligemia, and possible bronchiectasis; unrelated to X-linked McLeod neuroacanthocytosis.
Mucopurulent chronic bronchitis
Mucopurulent chronic bronchitis, also called chronic suppurative or purulent bronchitis, is chronic bronchitis with thick purulent sputum; ICD-11 CA20.11, ICD-10-CM J41.1, ICD-9 491.1, SNOMED CT 74417001.
Panlobular emphysema
Panlobular (panacinar) emphysema: emphysema subtype with diffuse destruction of the entire secondary pulmonary lobule, diffuse low attenuation on CT, lower-lobe predominance, classically linked to alpha-1 antitrypsin deficiency and also seen in smokers.
Simple chronic bronchitis
Simple chronic bronchitis (ICD-11 CA20.10, ICD-10 J41.0) is chronic mucus hypersecretion with productive cough but no airflow obstruction; also called chronic catarrhal or smokers bronchitis.