3 articles
Antiphospholipid syndrome in systemic lupus erythematosus
Antiphospholipid syndrome in systemic lupus erythematosus is a prothrombotic autoimmune state where antibodies cause blood clots and pregnancy complications, affecting roughly 30 to 40% of lupus patients.
Lupus anticoagulant
Lupus anticoagulant (LA) is an antiphospholipid antibody, usually IgG against beta2-glycoprotein I or prothrombin, that prolongs clotting tests in vitro yet promotes thrombosis in vivo; it is a key laboratory criterion for antiphospholipid syndrome, detected by dRVVT and aPTT, and easily confounded by anticoagulant drugs.
Neonatal antiphospholipid syndrome
Neonatal antiphospholipid syndrome, also known as Neonatal Hughes syndrome, is a rare autoimmune disorder in which newborns develop venous or arterial blood clots with antiphospholipid antibodies.