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Vascular skin lesions and cutaneous signs

51 articles

Mongolian spot

Mongolian spot, or congenital dermal melanocytosis, slate grey nevus: a benign blue-gray birthmark of newborns on the lower back and buttocks, affecting over 90% of East Asian infants, fading in early childhood, and often mistaken for bruising.

Multifocal infantile hemangioma with extracutenous involvement

Multifocal infantile hemangioma with extracutenous involvement, once called diffuse neonatal hemangiomatosis, is a rare disorder marked by numerous skin hemangiomas plus hemangiomas of internal organs such as the liver.

Nevus

Nevus (plural nevi), or mole: a benign, circumscribed skin lesion, usually a melanocytic proliferation. Types include common acquired, dysplastic, and congenital nevi; dysplastic and giant congenital nevi raise melanoma risk.

Non-thrombocytopenic purpura

Non-thrombocytopenic purpura (ICD-11 3B60; ICD-10-CM D69.2) is skin or mucous-membrane bleeding with a normal platelet count, caused by vascular, drug, congenital, or vitamin C deficiency factors, including senile purpura.

Papillary hemangioma

Papillary hemangioma (papillary capillary hemangioma, ORPHA:673543) is a rare benign cutaneous vascular tumor of the head and neck with intraluminal papillary projections and hyaline globules; it harbors GNAQ/GNA11 Q209L mutations and must be distinguished from glomeruloid hemangioma of POEMS syndrome.

Papule

Papule: a solid, elevated, palpable skin lesion ≤1 cm in diameter, a primary lesion in dermatology; examples include warts, nevi, lichen planus, acne, and insect bites; distinguished from plaque and nodule by size.

Partially involuting congenital hemangioma

Partially involuting congenital hemangioma (PICH) is a rare benign vascular tumor fully formed at birth that regresses like a RICH but stops partway, leaving a NICH-like residual lesion; ulceration is its hallmark complication.

Periorbital dark circles

Periorbital dark circles (periorbital hyperpigmentation, POH, ICHOR): bilateral darkened eyelid skin from pigment, visible vasculature, or structural shadowing; treated by cause with topicals, lasers, fillers, or surgery.

Petechiae

Petechiae are pinpoint, round spots of bleeding under the skin or mucous membranes, caused by blood escaping broken capillaries, that do not blanch when pressed.

Plane xanthoma

Plane xanthoma (planar xanthoma) is a flat, yellow xanthoma of the skin occurring as xanthelasma, palmar crease xanthoma, or diffuse plane xanthoma, signaling dyslipidemia, cholestasis, or hematologic disease.

Pseudomyogenic hemangioendothelioma

Pseudomyogenic hemangioendothelioma (epithelioid sarcoma-like hemangioendothelioma) is a rare intermediate vascular tumor of skin, soft tissue, and bone in young men, multifocal, locally recurrent, rarely metastatic, defined by FOSB gene fusions.

Rapidly involuting congenital hemangioma

Rapidly involuting congenital hemangioma (RICH, ORPHA:141184) is a rare benign vascular tumor fully formed in utero that shrinks rapidly after birth, usually within 6-14 months; GLUT1 negative, unlike infantile hemangioma.

Rash

Rash (dermatitis, skin rash): an area of irritated or swollen skin with color, texture, or feeling changes, caused by contact dermatitis, infections, drugs, or systemic disease; diagnosed by morphology and treated with steroids and antihistamines.

Reactive angioendotheliomatosis

Reactive angioendotheliomatosis (RAE) is a rare, benign, self-limiting cutaneous vascular proliferation with endothelial hyperplasia inside and around dermal vessels, occurring with systemic diseases such as endocarditis, renal disease, and peripheral vascular disease.

Salmon patch

Salmon patch (nevus simplex), also called stork bite or angel's kiss, is a benign capillary malformation birthmark present at birth in roughly 30-40% of newborns, appearing as a flat pink-red blanchable patch on the nape, eyelids, or glabella that usually fades within 1-2 years, though about half of nape lesions persist.

Spindle cell hemangioma

Spindle cell hemangioma, also called spindle cell hemangioendothelioma, is a rare benign vascular tumor of the dermis and subcutis with IDH1/IDH2 mutations, painful limb nodules, frequent local recurrence, and no metastatic potential.

Telangiectasia

Telangiectasia (telangiectases, broken capillaries) is the permanent dilation of small superficial blood vessels visible as fine red lines on skin or mucous membranes; causes include rosacea, sun damage, pregnancy, and HHT, treated by sclerotherapy or vascular lasers.

Traumatic purpura

Traumatic purpura is non-blanching purple discoloration from bleeding into the skin caused by physical trauma, including scratching, clothing friction, or rough handling, classified in ICD-11 as code EF31.

Tufted angioma

Tufted angioma, formerly known as angioblastoma of Nakagawa, is a rare, benign blood vessel tumor that usually forms on the skin of infants and young children.

Venous lake

Venous lake (senile hemangioma of lip, acquired venous hemangioma): benign compressible blue-purple vascular lesion from dilated venules, usually on the lower lip of people over 50; treated with laser, sclerotherapy, or cryotherapy.

Wrinkle

Wrinkle (rhytid): visible skin crease from aging, UV exposure, smoking, and expression; classified fine vs coarse and atrophic, elastotic, expressional, gravitational; treated with retinoids, botulinum toxin, fillers, lasers.