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Diseases and injuries

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Febuxostat

Febuxostat (Adenuric, Uloric) is a nonpurine xanthine oxidase inhibitor for hyperuricemia in gout, FDA-approved 2009; CARES showed higher cardiovascular death versus allopurinol, FAST did not, prompting a US boxed warning.

Fecal impaction

Fecal impaction (fecaloma): a compacted fecal mass at any intestinal level that cannot be evacuated spontaneously, usually from chronic constipation in elderly or neuropsychiatric patients; treated with enemas, manual disimpaction, or polyethylene glycol lavage, and complicated by perforation, obstruction, stercoral ulcer, and urinary retention.

Fecal incontinence

Fecal incontinence, or accidental bowel leakage, is uncontrolled passage of stool, affecting about 7.7 percent of adults. Causes include sphincter damage, childbirth, and neurological disease; treatment is stepwise from diet and pelvic floor training to nerve stimulation and surgery.

Feeding problems of newborn

Feeding problems of newborn (ICD-11 KD32) covers neonatal slow feeding, underfeeding, overfeeding, breast-feeding difficulty, and failure to thrive, arising from immature suck-swallow-breathe coordination, dysphagia, or prematurity.

Feeling ill

Feeling ill (malaise), ICD-11 code MG25, is a non-specific sensation of being unwell. Acute sickness behavior is cytokine-driven (IL-1β, IL-6, TNFα) and adaptive; it differs from chronic ME/CFS.

Feeling of incomplete bladder emptying

Feeling of incomplete bladder emptying (残尿感), an ICS-defined lower urinary tract symptom and ICD-11 code MF50.64: a complaint the bladder does not feel empty after urination, often but not always linked to high postvoid residual urine.

Feingold syndrome

Feingold syndrome (FGLDS, ODED syndrome) is a rare autosomal dominant congenital malformation disorder with microcephaly, digital anomalies, and learning deficit; type 1 from MYCN variants includes gastrointestinal atresia, type 2 from MIR17HG deletion does not.

Feline viral rhinotracheitis

Feline viral rhinotracheitis (FVR), also called feline herpesvirus 1 or felid alphaherpesvirus 1 infection, is an acute upper respiratory and ocular disease of cats; it causes about half of feline viral URIs, becomes latent for life, and is not zoonotic.

Felty's syndrome

Felty's syndrome (Chauffard-Still-Felty syndrome): rare triad of seropositive rheumatoid arthritis, splenomegaly, and neutropenia (ANC under 1500/mm3), described by Augustus Roi Felty in 1924, overlapping with T-LGL leukemia.

Female adnexal tumor of probable Wolffian origin

FATWO, female adnexal tumor of probable Wolffian origin, is a rare low-malignant-potential gynecologic neoplasm from mesonephric duct remnants, usually in the broad ligament, median age 50, treated by surgical resection.

Female dyspareunia

Female dyspareunia (ICD-11 GA12) is recurrent genital pain with intercourse or vaginal penetration from an identifiable physical cause; DSM-5 folds it into GPPPD. Prevalence 7.5% (Britain), 10-20% (US).

Female genital mutilation

Female genital mutilation, also called female genital cutting, is the removal of or harm to external female genitalia without medical justification, affecting over 230 million girls and women.

Female genital pain

Female genital pain: pain perceived in the pelvis, pelvic organs, vagina, or external genitals (ICD-11 GA34.6). Includes vulvodynia, dyspareunia, and pain from specific disorders; classified by the 2015 ISSVD, ISSWSH, and IPPS consensus.

Female pelvic pain

Female pelvic pain, ICD-11 GA34.2, is pelvic pain in women linked to internal genital organs or the menstrual cycle; subtypes cyclic and noncyclic; chronic form lasts over three months; causes include endometriosis and PID.

Femoral-facial syndrome

Femoral-facial syndrome, also called femoral hypoplasia-unusual facies syndrome, is a rare congenital disorder combining underdeveloped or absent femurs with distinctive facial features, often linked to maternal diabetes.

Femoroacetabular impingement

Femoroacetabular impingement (FAI, FAI syndrome): hip condition with cam, pincer, or combined extra bone causing abnormal joint contact, pain, labral and cartilage damage, and early osteoarthritis risk.

Femur-fibula-ulna complex

Femur-fibula-ulna complex (FFU complex, femur-fibula-ulna syndrome, OMIM 228200) is a rare, sporadic, non-lethal congenital limb malformation with asymmetric hypoplasia or absence of the femur, fibula, and/or ulna; right side and upper limbs more often affected.

Fenoldopam

Fenoldopam, sold as Corlopam and known as SKF 82526, is a short-acting benzazepine drug given by intravenous infusion in hospitals to rapidly lower severe high blood pressure while preserving kidney blood flow.

Ferric carboxymaltose

Ferric carboxymaltose (Injectafer, Ferinject) is an intravenous iron(III)-hydroxide carbohydrate complex approved in 2013 for iron deficiency anemia; notable for single high-dose dosing and FGF23-mediated hypophosphatemia risk, now under an FDA boxed warning.

Ferric maltol

Ferric maltol (Feraccru, Accrufer) is an oral ferric iron-trimaltol complex for iron deficiency with or without anemia, approved in Europe and the US, dosed 30 mg twice daily, with gastrointestinal tolerability better than ferrous salts.

Ferro-cerebro-cutaneous syndrome

Ferro-cerebro-cutaneous syndrome, also known as neurodevelopmental disorder with epilepsy and hemochromatosis, is a rare X-linked condition caused by PIGA gene mutations, with seizures, skin abnormalities, and body-wide iron overload beginning in infancy.

Ferrous bisglycinate

Ferrous bisglycinate (ferrous bis-glycine chelate, FeBC), an iron(II)-glycine amino acid chelate supplement and fortificant; GRAS (GRN 19, 1999); higher bioavailability and fewer GI side effects than iron salts, though clinical superiority is unproven.

Ferumoxytol

Ferumoxytol, sold as Feraheme, is an intravenous iron replacement drug approved in the United States in 2009 for iron deficiency anemia in adults, especially with chronic kidney disease.

Fetal acetylcholine receptor antibody-related disorder

FARAD, fetal acetylcholine receptor antibody-related disorder, also called FARIS: maternal anti-fetal-AChR antibodies cross the placenta, causing arthrogryposis to persistent myopathy; preventable with pregnancy immunotherapy, salbutamol helps survivors.

Fetal akinesia deformation sequence

Fetal akinesia deformation sequence (FADS, Pena-Shokeir phenotype/syndrome type I): heterogeneous pattern of fetal akinesia, arthrogryposis, growth retardation, lung hypoplasia, and facial anomalies from any cause of absent fetal movement.

Fetal alcohol syndrome

Fetal alcohol syndrome (FAS), also called syndrome alcoolique foetal, is the most severe fetal alcohol spectrum disorder: a teratogenic malformation syndrome from maternal drinking in pregnancy, marked by growth deficiency, three facial anomalies, and CNS impairment.

Fetal blood loss

Fetal blood loss (ICD-11 KA80, 胎児失血) is loss of blood from the fetal circulation during pregnancy, labour, or delivery, including fetomaternal hemorrhage, vasa praevia, ruptured cord, and co-twin hemorrhage, causing fetal anemia or death.

Fetal carbamazepine syndrome

Fetal carbamazepine syndrome, a drug embryofetopathy from prenatal carbamazepine exposure: facial dysmorphism, nail hypoplasia, spina bifida, cardiac and cleft anomalies, dose-dependent malformation risk.

Fetal cytomegalovirus syndrome

Fetal cytomegalovirus syndrome, also called congenital CMV (cCMV), results from transplacental CMV infection of the fetus; about 1 in 200 US newborns is infected, 1 in 5 develops sequelae, and sensorineural hearing loss is the leading disability.

Fetal echocardiography

Fetal echocardiography is a detailed prenatal ultrasound of the fetal heart, the gold standard for diagnosing congenital heart disease before birth, typically performed at 18-22 weeks for high-risk pregnancies or abnormal screening.