8,704 articles
Enuresis
Enuresis (nocturnal enuresis, bedwetting): involuntary urination during sleep at age 5 or older without neurological disease. Classified primary/secondary and mono/non-monosymptomatic; driven by nocturnal polyuria, small bladder capacity, and high arousal threshold; treated with alarm therapy and desmopressin.
Enzalutamide
Enzalutamide (Xtandi, formerly MDV3100) is an oral second-generation androgen receptor inhibitor approved in 2012 for prostate cancer, dosed 160 mg daily, used across CRPC, nmCRPC, and mCSPC settings.
EoL-1
EoL-1, also written EOL-1, is a human eosinophilic leukemia cell line established from the blood of a 33-year-old man, known for carrying the FIP1L1-PDGFRA fusion kinase.
Eosinopenia
Eosinopenia, a decreased blood eosinophil count (normal 0–500 cells/µL), occurs in acute stress, inflammation, glucocorticoid use, and bacterial infection; studied as a cheap rule-in infection marker, less accurate than CRP.
Eosinophilia
Eosinophilia: elevated blood eosinophil count (>500/µL, 0.5×10^9/L), also called hypereosinophilia above 1.5×10^9/L. Causes include allergy, drugs, parasites, and clonal blood disorders such as FIP1L1::PDGFRA disease.
Eosinophilic angiocentric fibrosis
Eosinophilic angiocentric fibrosis (EAF), also called IgG4-related eosinophilic angiocentric fibrosis, is a rare benign fibroinflammatory sinonasal lesion with onion-skin perivascular fibrosis, eosinophil-rich infiltrate, partial IgG4-related disease overlap, and frequent recurrence after resection.
Eosinophilic colitis
Eosinophilic colitis, also called eosinophilic colitis (EoC), is a rare eosinophilic gastrointestinal disease with eosinophil-rich colon inflammation of no secondary cause, peaking in neonates and young adults.
Eosinophilic cystitis
Eosinophilic cystitis (EC), a rare inflammatory bladder disease first described in 1960, features eosinophilic infiltration of the bladder wall, hematuria and frequency, diagnosis by cystoscopic biopsy, and steroid-antihistamine treatment with frequent recurrence.
Eosinophilic duodenitis
Eosinophilic duodenitis (EoD), also called eosinophilic enteritis of the duodenum, is a non-esophageal eosinophilic gastrointestinal disease with excess duodenal mucosal eosinophils; diagnosed by biopsy thresholds (about 30-50 eos/hpf) after excluding other causes.
Eosinophilic esophagitis
Eosinophilic esophagitis, also called allergic eosinophilic esophagitis, is a chronic immune-mediated disease of the esophagus and a leading cause of difficulty swallowing in children and young adults.
Eosinophilic fasciitis
Eosinophilic fasciitis, or Shulman syndrome, is a rare fibrosing disorder of the fascia first described by Shulman in 1974, causing scleroderma-like limb induration with eosinophilia in 63-93% of cases, sparing the fingers, and treated with corticosteroids.
Eosinophilic granuloma
Eosinophilic granuloma, also called eosinophilic granuloma of bone, is the most common, usually unifocal bone form of Langerhans cell histiocytosis, a benign tumor-like proliferation of Langerhans cells treated by observation, steroid injection, or curettage.
Eosinophilic granulomatosis with polyangiitis
Eosinophilic granulomatosis with polyangiitis, formerly known as Churg-Strauss syndrome, is a rare ANCA-associated vasculitis first reported in 1951, defined by asthma, eosinophilia, and necrotizing inflammation of small and medium blood vessels.
Eosinophilic meningitis due to Angiostrongylus cantonensis
Eosinophilic meningitis due to Angiostrongylus cantonensis, also called neuroangiostrongyliasis, is meningitis with eosinophils in the spinal fluid, caused by rat lungworm larvae in raw snails, slugs, or crustaceans.
Eosinophilic myocarditis
Eosinophilic myocarditis (EM), also called Löffler endomyocarditis in its chronic form, is a rare inflammatory cardiomyopathy with eosinophilic infiltration of the heart muscle, caused by hypersensitivity, EGPA, HES, parasites, or idiopathic factors, and treated with cause-specific therapy plus corticosteroids.
Eosinophilic peritonitis
Eosinophilic peritonitis, also called peritoneal fluid eosinophilia, is a rare non-infectious, presumably allergic PD complication with eosinophil-rich cloudy dialysate, negative cultures, onset within a month of catheter insertion, treated with steroids or antihistamines.
Epidemic myalgia
Epidemic myalgia, or Bornholm disease, devil's grip, epidemic pleurodynia (myalgia epidemica), is a febrile enteroviral illness, usually coxsackievirus B, causing severe pleuritic chest pain; first described on Bornholm in 1930 by Sylvest.
Epidemiological method
Epidemiological method: the systematic population-level approach of defining cases, counting and describing them by time, place, and person, calculating rates, and comparing groups; also called the epidemiologic approach, rooted in John Snow's 1854 cholera work.
Epidemiology and history of acute lymphoblastic leukemia
The epidemiology and history of acute lymphoblastic leukemia covers a cancer peaking at ages 1 to 4, transformed since 1948 from fatal to largely curable in children.
Epidemiology and risk factors of Hodgkin lymphoma
The epidemiology of Hodgkin lymphoma, a rare lymphatic cancer, features peaks in young adulthood and late life, with EBV, HIV, and family history as risk factors.
Epidemiology of endometriosis
The epidemiology of endometriosis describes how frequently the disease occurs, in whom, and which factors raise risk, with prevalence estimates contested between 1 and 10 percent.
Epidemiology of hemoglobinopathies
The epidemiology of hemoglobinopathies studies inherited hemoglobin disorders like sickle-cell disease and thalassemia, which about 5% of people carry and which malaria selection concentrated in the tropics.
Epidemiology of HIV/AIDS
Epidemiology of HIV/AIDS: global distribution, incidence, prevalence, and mortality of HIV infection and AIDS. 41.0 million people living with HIV in 2025, 1.2 million new infections, 570,000 deaths, concentrated in the WHO African Region and key populations.
Epidemiology of orofacial clefts
The epidemiology of orofacial clefts studies how often cleft lip and cleft palate occur, roughly 1 in 700 live births, with rates varying by region and ancestry.
Epidemiology of stroke
The epidemiology of stroke is the study of how stroke is distributed across populations; in 2021 it caused 11.9 million new strokes and 7.3 million deaths.
Epidemiology of syphilis
Epidemiology of syphilis: distribution and trends of Treponema pallidum infection. WHO estimates 8 million adult cases in 2022; resurgence since 2000 among MSM, with congenital syphilis rising sharply in the US and Europe.
Epidermal naevus
Epidermal naevus (epidermal nevus): benign overgrowth of the epidermis present at birth or early childhood, following Blaschko lines, caused by mosaic FGFR3, PIK3CA, or RAS mutations, sometimes syndromic.
Epidermal nevus syndrome
Epidermal nevus syndrome (ENS, Orphanet ORPHA:35125) is a group of rare mosaic disorders combining epidermal nevi with extracutaneous abnormalities of the brain, eyes, skeleton, and other systems, caused by postzygotic RAS-pathway mutations.
Epidermodysplasia verruciformis
Epidermodysplasia verruciformis (EV, Lewandowsky-Lutz disease) is a rare autosomal recessive genodermatosis causing beta-HPV susceptibility, flat warts, and 30-60% skin cancer risk, linked to TMC6/EVER1 or TMC8/EVER2 mutations.
Epidermoid cyst
Epidermoid cyst (epidermal inclusion cyst, follicular infundibular cyst), a benign keratin-filled skin cyst from the hair follicle infundibulum; not a sebaceous cyst; firm 1–3 cm nodule with central punctum, treated by complete excision.